Transcriptome Analysis Introduction and Examples from the Neurosciences /

The goal of this book is to be an accessible guide for undergraduate and graduate students to the new field of data-driven biology. Next-generation sequencing technologies have put genome-scale analysis of gene expression into the standard toolbox of experimental biologists. Yet, biological interpre...

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Hlavní autor: Cellerino, Alessandro (Autor)
Médium: Elektronický zdroj E-kniha
Jazyk:angličtina
Vydáno: Pisa : Scuola Normale Superiore, 2018.
Vydání:1st ed. 2018.
Edice:Lecture Notes (Scuola Normale Superiore) ; 17
Témata:
Biomathematics.
Bioinformatics.
Systems biology.
ISBN:9788876426421
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Obsah:
  • Preface
  • Introduction: why study transcriptomics?
  • 1. Data distribution and visualisation
  • 2. Next-generation RNA sequencing
  • 3. RNA-seq raw data processing
  • 4. Differentially expressed gene detection & analysis
  • 5. Unbiased clustering methods
  • 6. Knowledge-based clustering methods
  • 7. Network analysis
  • 8. Mesoscale transcriptome analysis
  • 9. Microscale transcriptome analysis
  • Bibliography
  • Index.

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