Precision Molecular Pathology of Lung Cancer

This new edition provides the latest information and insights into the molecular basis for lung cancer. Since the publication of the previous edition of this volume, dramatic changes have occurred with the classification of lung cancer, biomarker testing, and molecular therapy. The book covers these...

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Médium: Elektronický zdroj E-kniha
Jazyk:English
Vydavateľské údaje: Cham : Springer International Publishing, 2018.
Vydanie:2nd ed. 2018.
Edícia:Molecular Pathology Library,
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ISBN:9783319629414
ISSN:1935-987X
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Obsah:
  • I. Background
  • 1. Precision Medicine of Lung Cancer: Introduction
  • 2. Lung Cancer Epidemiology and Demographics
  • 3. Genetic Susceptibility to Lung Cancer
  • 4. Lung Cancer Stem Cells
  • 5. The 2015 World Health Organization Classification of Lung Cancer: Overview
  • II. Testing Methods
  • 6. Preanalytic considerations
  • 7. Mutation testing of lung cancer biomarkers
  • 8. Translocation testing of lung cancer biomarkers
  • 9. Immunohistochemistry of lung cancer biomarkers
  • 10. Next Generation and Third Generation Sequencing of lung cancer biomarkers
  • III. Molecular Pathology of Specific Cell Types
  • 11. Mutations as Predictive Biomarkers for Adenocarcinoma
  • 12. Translocations as predictive Biomarkers for Adenocarcinoma
  • 13. Predictive Biomarkers for Squamous Cell Carcinoma
  • 14. Molecular Pathology of Small Cell Carcinoma
  • 15. Molecular Pathology of Uncommon Carcinomas
  • 16. Molecular Pathology of Lung Cancer Metastases
  • 17. Molecular Pathology of Precursor and Preinvasive Lesions
  • IV. General and Emerging Fields in Molecular Pathology of Lung Cancer
  • 18. Prognostic biomarkers in lung cancer
  • 19. Biomarkers and Differing Therapy Modalities
  • 20. Immuno-oncology of Lung Cancer
  • 21. Liquid Biopsy.