Protein-Protein and Domain-Domain Interactions

This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describ...

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Hlavní autor: Kangueane, Pandjassarame (Autor)
Médium: Elektronický zdroj E-kniha
Jazyk:angličtina
Vydáno: Singapore : Springer Singapore , 2018.
Vydání:1st ed. 2018.
Témata:
Medical genetics.
Bioinformatics.
Proteins .
Vaccines.
ISBN:9789811073472
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Obsah:
  • Module 1. Preface
  • Module 2. Introduction to protein complexes
  • Module 3. Historical advancement
  • Module 4. Databases for protein complexes
  • Module 5. Types of protein complexes
  • Module 6. Hetero dimer protein complexes
  • Module 7. Homo dimer protein complexes
  • Module 8. Multimer protein complexes
  • Module 9. Interfaces in protein complexes
  • Module 10. Principles of protein-protein binding
  • Module 11. Homodimer folding and binding
  • Module 12. Gene fusion and protein complexes
  • Module 13. Domain-domain interactions
  • Module 14. Protein docking: Methods, software tools and servers
  • Module 15. Protein complexes, pathways and networks
  • Module 16. Protein complexes and biological functions
  • Module 17. Protein complexes in diseases
  • Module 18. Protein complexes in drug discovery & vaccine development
  • Module 19. Protein complexes in genome and proteome analysis
  • Module 20. Conclusions & challenges.

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