Multiscale Mechanobiology of Bone Remodeling and Adaptation

The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during...

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Bibliographic Details
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing, 2018.
Edition:1st ed. 2018.
Series:CISM International Centre for Mechanical Sciences, Courses and Lectures, 578
Subjects:
ISBN:9783319588452
ISSN:0254-1971 ;
Online Access: Get full text
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041 |a eng 
245 1 0 |a Multiscale Mechanobiology of Bone Remodeling and Adaptation  |h [electronic resource] /  |c edited by Peter Pivonka. 
250 |a 1st ed. 2018. 
260 1 |a Cham :  |b Springer International Publishing,  |c 2018. 
300 |a XII, 287 p. 98 illus.  |b online resource. 
490 1 |a CISM International Centre for Mechanical Sciences, Courses and Lectures,  |x 0254-1971 ;  |v 578 
500 |a Engineering  
505 0 |a Bone cell biology and mechanobiology -- Disease systems analysis of osteoporosis and treatments -- Bone quality assessment across the scales -- Interaction of bone tissue with other tissues including muscle, cartilage, and vascularization -- Musculoskeletal modeling of human movement -- Image-based 3D micro-FE modeling. 
516 |a text file PDF 
520 |a The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations. 
650 0 |a Mechanics. 
650 0 |a Mechanics, Applied. 
650 0 |a Biomaterials. 
650 0 |a Orthopedics. 
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