Modeling Methods for Medical Systems Biology Regulatory Dynamics Underlying the Emergence of Disease Processes /

This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes u...

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Bibliographic Details
Main Author: Álvarez-Buylla Roces, María Elena (Author)
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing, 2018.
Edition:1st ed. 2018.
Series:Advances in Experimental Medicine and Biology, 1069
Subjects:
Systems biology.
Microbial genetics.
Microbial genomics.
Mathematical models.
Bioinformatics.
ISBN:9783319893549
ISSN:0065-2598 ;
Online Access: Get full text
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Summary:This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.
Item Description:Biomedical and Life Sciences
Physical Description:XXI, 258 p. 60 illus. in color. online resource.
ISBN:9783319893549
ISSN:0065-2598 ;

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