Molecular Recognition of DNA Double Helix Gene Regulation and Photochemistry of BrU Substituted DNA /

In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to...

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Hlavní autor: Saha, Abhijit (Autor)
Médium: Elektronický zdroj E-kniha
Jazyk:angličtina
Vydáno: Singapore : Springer Singapore , 2018.
Vydání:1st ed. 2018.
Edice:Springer Theses, Recognizing Outstanding Ph.D. Research,
Témata:
Bioorganic chemistry.
Nucleic acids.
Regenerative medicine.
Tissue engineering.
ISBN:9789811087462
ISSN:2190-5053
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Obsah:
  • 1. Overview of DNA minor groove binding synthetic small molecules and photochemistry of BrU substituted DNA
  • 2. Synthesis and Biological Evaluation of Targeted Transcriptional Activator with HDAC8 Inhibitory Activity
  • 3. Chemical Modification of a Synthetic Small Molecule Boosts its Biological Efficacy against Pluripotency Genes in Mouse Fibroblast
  • 4. Development of a novel photochemical detection technique for the analysis of polyamide binding sites
  • 5. Examining cooperative binding of Sox2 on DC5 regulatory element upon complex formation with Pax6 through excess electron transfer assay
  • 6.UVA irradiation of BrU-substituted DNA in the presence of Hoechst 33258. .

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