Zobraziť v EDS

Protein structure prediction and design on near-term quantum computers

Uložené v:
Podrobná bibliografia
Názov: Protein structure prediction and design on near-term quantum computers
Autori: Linn, Hanna, 1995
Zdroj: Wallenberg Centre for Quantum Technology (WACQT).
Predmety: variational quantum algorithms, quantum approximate optimization algorithm, hardware-efficient ansatz, protein design, quantum walk, life science, protein structure prediction, near-term intermediate-scale quantum devices, protein folding
Popis: In the convergence of quantum computing and life science, we explore protein structure prediction and design on near-term intermediate-scale quantum devices. We investigate the algorithmic and resource constraints of today’s quantum computers, aiming to assess their potential in solving biologically relevant problems. We describe key variational quantum algorithms, including the problem-informed Quantum Approximate Optimization Algorithm and the problem-agnostic Hardware-Efficient Ansatz. Additionally, quantum walks are examined. The computationally complex coarse-grained lattice models in protein structure prediction and design are discussed. Quantum algorithms are then applied to these models to address the utility and limitations of today’s quantum computers. The thesis critically evaluates the limitations of quantum methods in comparison to classical approaches, highlighting the trade-offs between resource requirements in today’s quantum devices and the performance of quantum algorithms. Through this interdisciplinary investigation, the work contributes to understanding how quantum algorithms may advance computational biology in today’s quantum computing landscape.
Popis súboru: electronic
Prístupová URL adresa: https://research.chalmers.se/publication/548680
https://research.chalmers.se/publication/548680/file/548680_Fulltext.pdf
Databáza: SwePub
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://research.chalmers.se/publication/548680#
    Name: EDS - SwePub (s4221598)
    Category: fullText
    Text: View record in SwePub
  – Url: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=EBSCO&SrcAuth=EBSCO&DestApp=WOS&ServiceName=TransferToWoS&DestLinkType=GeneralSearchSummary&Func=Links&author=Linn%20H
    Name: ISI
    Category: fullText
    Text: Nájsť tento článok vo Web of Science
    Icon: https://imagesrvr.epnet.com/ls/20docs.gif
    MouseOverText: Nájsť tento článok vo Web of Science
Header DbId: edsswe
DbLabel: SwePub
An: edsswe.oai.research.chalmers.se.76f14162.d649.44af.981d.d168cf2ec3ec
RelevancyScore: 987
AccessLevel: 6
PubType:
PubTypeId: unknown
PreciseRelevancyScore: 986.736389160156
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Protein structure prediction and design on near-term quantum computers
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Linn%2C+Hanna%22">Linn, Hanna</searchLink>, 1995
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <i>Wallenberg Centre for Quantum Technology (WACQT)</i>.
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22variational+quantum+algorithms%22">variational quantum algorithms</searchLink><br /><searchLink fieldCode="DE" term="%22quantum+approximate+optimization+algorithm%22">quantum approximate optimization algorithm</searchLink><br /><searchLink fieldCode="DE" term="%22hardware-efficient+ansatz%22">hardware-efficient ansatz</searchLink><br /><searchLink fieldCode="DE" term="%22protein+design%22">protein design</searchLink><br /><searchLink fieldCode="DE" term="%22quantum+walk%22">quantum walk</searchLink><br /><searchLink fieldCode="DE" term="%22life+science%22">life science</searchLink><br /><searchLink fieldCode="DE" term="%22protein+structure+prediction%22">protein structure prediction</searchLink><br /><searchLink fieldCode="DE" term="%22near-term+intermediate-scale+quantum+devices%22">near-term intermediate-scale quantum devices</searchLink><br /><searchLink fieldCode="DE" term="%22protein+folding%22">protein folding</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: In the convergence of quantum computing and life science, we explore protein structure prediction and design on near-term intermediate-scale quantum devices. We investigate the algorithmic and resource constraints of today’s quantum computers, aiming to assess their potential in solving biologically relevant problems. We describe key variational quantum algorithms, including the problem-informed Quantum Approximate Optimization Algorithm and the problem-agnostic Hardware-Efficient Ansatz. Additionally, quantum walks are examined. The computationally complex coarse-grained lattice models in protein structure prediction and design are discussed. Quantum algorithms are then applied to these models to address the utility and limitations of today’s quantum computers. The thesis critically evaluates the limitations of quantum methods in comparison to classical approaches, highlighting the trade-offs between resource requirements in today’s quantum devices and the performance of quantum algorithms. Through this interdisciplinary investigation, the work contributes to understanding how quantum algorithms may advance computational biology in today’s quantum computing landscape.
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: electronic
– Name: URL
  Label: Access URL
  Group: URL
  Data: <link linkTarget="URL" linkTerm="https://research.chalmers.se/publication/548680" linkWindow="_blank">https://research.chalmers.se/publication/548680</link><br /><link linkTarget="URL" linkTerm="https://research.chalmers.se/publication/548680/file/548680_Fulltext.pdf" linkWindow="_blank">https://research.chalmers.se/publication/548680/file/548680_Fulltext.pdf</link>
PLink https://erproxy.cvtisr.sk/sfx/access?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsswe&AN=edsswe.oai.research.chalmers.se.76f14162.d649.44af.981d.d168cf2ec3ec
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.63959/chalmers.dt/5762
    Languages:
      – Text: English
    Subjects:
      – SubjectFull: variational quantum algorithms
        Type: general
      – SubjectFull: quantum approximate optimization algorithm
        Type: general
      – SubjectFull: hardware-efficient ansatz
        Type: general
      – SubjectFull: protein design
        Type: general
      – SubjectFull: quantum walk
        Type: general
      – SubjectFull: life science
        Type: general
      – SubjectFull: protein structure prediction
        Type: general
      – SubjectFull: near-term intermediate-scale quantum devices
        Type: general
      – SubjectFull: protein folding
        Type: general
    Titles:
      – TitleFull: Protein structure prediction and design on near-term quantum computers
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Linn, Hanna
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-locals
              Value: SWEPUB_FREE
            – Type: issn-locals
              Value: CTH_SWEPUB
          Titles:
            – TitleFull: Wallenberg Centre for Quantum Technology (WACQT)
              Type: main
ResultId 1