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HARMLESS Early Warning System for Advanced Materials

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Title: HARMLESS Early Warning System for Advanced Materials
Authors: Prinz, Julia, Nagel, Gregor, Dekkers, Susan, van Someren, Eugene P., Adam, Veronique, Di Battista, Veronica, Suarez-Merino, Blanca, Wohlleben, Wendel, Persson, Michael, 1956, Baun, Anders, Schmid, Otmar, Haase, Andrea
Source: ADVANCED SUSTAINABLE SYSTEMS. In Press
Subject Terms: regulatory preparedness, risk assessment, safe-and sustainable-by-design, sustainability, early warning system, advanced materials
Description: Advanced Materials (AdMa) play a crucial role for numerous strategies that address global challenges. They are being developed fast, making it increasingly challenging for regulation to keep pace with innovation. Existing frameworks, which are either not designed for AdMa or lack adequate filtering to identify AdMa of high concern, do not (yet) effectively support regulatory preparedness. The HARMLESS Early Warning System (EWS), in contrast, is a practically applicable tool for screening plenty of materials in a reasonable time. It is organized in two tiers, each underpinned by a specific methodology and facilitated by a dedicated online tool. The initial Tier 0 categorizes the materials using the Advanced Materials Earliest Assessment (AMEA) tool. Tier 1 first screens materials asking only 15 questions and is ideal for data-poor materials at early innovation stages. These questions cover issues related to human/ environmental exposure and hazard, sustainability and applicability of existing regulations. In a more elaborated version, experimental testing based on New Approach Methodologies (NAMs) is suggested. As outcome, the user is provided with 1) material-related concerns, 2) prioritization of AdMa and 3) recommendations for (regulatory) follow-up actions. Data from two industrial case studies is presented to demonstrate the applicability of the HARMLESS EWS.
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  Data: HARMLESS Early Warning System for Advanced Materials
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  Data: <searchLink fieldCode="AR" term="%22Prinz%2C+Julia%22">Prinz, Julia</searchLink><br /><searchLink fieldCode="AR" term="%22Nagel%2C+Gregor%22">Nagel, Gregor</searchLink><br /><searchLink fieldCode="AR" term="%22Dekkers%2C+Susan%22">Dekkers, Susan</searchLink><br /><searchLink fieldCode="AR" term="%22van+Someren%2C+Eugene+P%2E%22">van Someren, Eugene P.</searchLink><br /><searchLink fieldCode="AR" term="%22Adam%2C+Veronique%22">Adam, Veronique</searchLink><br /><searchLink fieldCode="AR" term="%22Di+Battista%2C+Veronica%22">Di Battista, Veronica</searchLink><br /><searchLink fieldCode="AR" term="%22Suarez-Merino%2C+Blanca%22">Suarez-Merino, Blanca</searchLink><br /><searchLink fieldCode="AR" term="%22Wohlleben%2C+Wendel%22">Wohlleben, Wendel</searchLink><br /><searchLink fieldCode="AR" term="%22Persson%2C+Michael%22">Persson, Michael</searchLink>, 1956<br /><searchLink fieldCode="AR" term="%22Baun%2C+Anders%22">Baun, Anders</searchLink><br /><searchLink fieldCode="AR" term="%22Schmid%2C+Otmar%22">Schmid, Otmar</searchLink><br /><searchLink fieldCode="AR" term="%22Haase%2C+Andrea%22">Haase, Andrea</searchLink>
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  Data: <i>ADVANCED SUSTAINABLE SYSTEMS</i>. In Press
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  Data: <searchLink fieldCode="DE" term="%22regulatory+preparedness%22">regulatory preparedness</searchLink><br /><searchLink fieldCode="DE" term="%22risk+assessment%22">risk assessment</searchLink><br /><searchLink fieldCode="DE" term="%22safe-and+sustainable-by-design%22">safe-and sustainable-by-design</searchLink><br /><searchLink fieldCode="DE" term="%22sustainability%22">sustainability</searchLink><br /><searchLink fieldCode="DE" term="%22early+warning+system%22">early warning system</searchLink><br /><searchLink fieldCode="DE" term="%22advanced+materials%22">advanced materials</searchLink>
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  Label: Description
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  Data: Advanced Materials (AdMa) play a crucial role for numerous strategies that address global challenges. They are being developed fast, making it increasingly challenging for regulation to keep pace with innovation. Existing frameworks, which are either not designed for AdMa or lack adequate filtering to identify AdMa of high concern, do not (yet) effectively support regulatory preparedness. The HARMLESS Early Warning System (EWS), in contrast, is a practically applicable tool for screening plenty of materials in a reasonable time. It is organized in two tiers, each underpinned by a specific methodology and facilitated by a dedicated online tool. The initial Tier 0 categorizes the materials using the Advanced Materials Earliest Assessment (AMEA) tool. Tier 1 first screens materials asking only 15 questions and is ideal for data-poor materials at early innovation stages. These questions cover issues related to human/ environmental exposure and hazard, sustainability and applicability of existing regulations. In a more elaborated version, experimental testing based on New Approach Methodologies (NAMs) is suggested. As outcome, the user is provided with 1) material-related concerns, 2) prioritization of AdMa and 3) recommendations for (regulatory) follow-up actions. Data from two industrial case studies is presented to demonstrate the applicability of the HARMLESS EWS.
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      – Type: doi
        Value: 10.1002/adsu.202500217
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      – Text: English
    Subjects:
      – SubjectFull: regulatory preparedness
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      – SubjectFull: advanced materials
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      – TitleFull: HARMLESS Early Warning System for Advanced Materials
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            – D: 01
              M: 01
              Type: published
              Y: 2025
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