Vertical graphene nanoarray decorated with Ag nanoparticles exhibits enhanced antibacterial effects

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Název: Vertical graphene nanoarray decorated with Ag nanoparticles exhibits enhanced antibacterial effects
Autoři: Zhang, Jian, 1989, Pandit, Santosh, 1987, Rahimi, Shadi, 1982, Cao, Zhejian, 1991, Mijakovic, Ivan, 1975
Zdroj: Graphene-based drug delivery systems for treating MRSA infections Förstå interaktionen mellan grafenbaserad beläggning på tandimplantat och perio-implantibakterier Grafenbaserad CRISPR-Cas9 genmodifiering av växtceller Graphene-based CRISPR-Cas 9 gene modification to plant cells Journal of Colloid and Interface Science. 676:808-816
Témata: Ag nanoparticles, Antibacterial properties, Vertical graphene, Cytotoxicity, Polydopamine
Popis: Bacterial infection of biomedical implants is an important clinical challenge, driving the development of novel antimicrobial materials. The antibacterial effect of vertically aligned graphene as a nanoarray coating has been reported. In this study, vertically aligned graphene nanosheets decorated with silver nanoparticles were fabricated to enhance antibacterial effectiveness. Vertical graphene (VG) nanoflakes were synthesized by plasma-enhanced chemical vapor deposition (PECVD). Ag nanoparticles were attached to the surface of VG through using polydopamine and achieving a sustained release of Ag+. VG loaded with Ag nanoparticles (VGP/Ag) not only prevented bacterial adhesion for a long time, but also exhibited good biocompatibility. This work provides a new venue for designing antibacterial surfaces based on combination of graphene nanoarrays with other nanomaterials, and the results indicate that this approach could be very successful in preventing implant associated infections.
Popis souboru: electronic
Přístupová URL adresa: https://research.chalmers.se/publication/546519
https://research.chalmers.se/publication/546519/file/546519_Fulltext.pdf
Databáze: SwePub
Popis
Abstrakt:Bacterial infection of biomedical implants is an important clinical challenge, driving the development of novel antimicrobial materials. The antibacterial effect of vertically aligned graphene as a nanoarray coating has been reported. In this study, vertically aligned graphene nanosheets decorated with silver nanoparticles were fabricated to enhance antibacterial effectiveness. Vertical graphene (VG) nanoflakes were synthesized by plasma-enhanced chemical vapor deposition (PECVD). Ag nanoparticles were attached to the surface of VG through using polydopamine and achieving a sustained release of Ag+. VG loaded with Ag nanoparticles (VGP/Ag) not only prevented bacterial adhesion for a long time, but also exhibited good biocompatibility. This work provides a new venue for designing antibacterial surfaces based on combination of graphene nanoarrays with other nanomaterials, and the results indicate that this approach could be very successful in preventing implant associated infections.
ISSN:10957103
00219797
DOI:10.1016/j.jcis.2024.07.173