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Mass spectrometry peptidomics data from infected and uninfected porcine wounds

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Titel: Mass spectrometry peptidomics data from infected and uninfected porcine wounds
Autoren: Forsberg, Fredrik, Kjellström, Sven, Petrlova, Jitka, Puthia, Manoj, Schmidtchen, Artur, Malmström, Johan, Hartman, Erik
Weitere Verfasser: Lund University, Faculty of Medicine, Department of Experimental Medical Science, Extracellular signaling and cell fate, Lunds universitet, Medicinska fakulteten, Institutionen för experimentell medicinsk vetenskap, Extracellulär signalering och cellöde, Originator, Lund University, Profile areas and other strong research environments, Strategic research areas (SRA), StemTherapy: National Initiative on Stem Cells for Regenerative Therapy, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Strategiska forskningsområden (SFO), StemTherapy: National Initiative on Stem Cells for Regenerative Therapy, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section III, Dermatology and Venereology (Lund), Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion III, Dermatologi och venereologi, Lund, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section V, Mass Spectrometry, BioMS, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion V, Masspektrometri, BioMS, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section V, Mass Spectrometry, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion V, Masspektrometri, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section III, Dermatology and Venereology (Lund), Schmidtchen Lab, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion III, Dermatologi och venereologi, Lund, Schmidtchen lab, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Infect@LU, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Infect@LU, Originator, Lund University, Profile areas and other strong research environments, Lund University Profile areas, LU Profile Area: Light and Materials, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Lunds universitets profilområden, LU profilområde: Ljus och material, Originator, Lund University, Faculty of Engineering, LTH, LTH Profile areas, LTH Profile Area: Engineering Health, Lunds universitet, Lunds Tekniska Högskola, LTH profilområden, LTH profilområde: Teknik för hälsa, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section III, Infection Medicine (BMC), epIgG, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion III, Infektionsmedicin, epIgG, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section III, Infection Medicine (BMC), SEBRA Sepsis and Bacterial Resistance Alliance, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion III, Infektionsmedicin, SEBRA Sepsis and Bacterial Resistance Alliance, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section III, Infection Medicine (BMC), Infection Medicine Proteomics, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion III, Infektionsmedicin, Infection Medicine Proteomics, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section III, Infection Medicine (BMC), Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion III, Infektionsmedicin, Originator
Quelle: Scientific Data. 12:1-6
Schlagwörter: Natural Sciences, Chemical Sciences, Analytical Chemistry, Naturvetenskap, Kemi, Analytisk kemi
Beschreibung: Recently, mass spectrometry based peptidomics studies have proven useful in the identification of biomarkers and bioactive peptide-based therapeutics. Here, we present a dataset comprised of temporal wound fluid peptidomics data from highly defined porcine models. Wound fluids from porcine wounds infected with Staphylococcus aureus and Pseudomonas aeruginosa, and uninfected controls, were sampled at different timepoints of the infection. Peptides were extracted from the samples, followed by liquid chromatography tandem mass spectrometry analysis in data dependent acquisition mode. The resulting spectra and searched files have been deposited to online repositories and made easily accessible to enable further investigations of the infected and uninfected wound fluid peptidome.
Zugangs-URL: https://doi.org/10.1038/s41597-025-05842-8
Datenbank: SwePub
Beschreibung
Abstract:Recently, mass spectrometry based peptidomics studies have proven useful in the identification of biomarkers and bioactive peptide-based therapeutics. Here, we present a dataset comprised of temporal wound fluid peptidomics data from highly defined porcine models. Wound fluids from porcine wounds infected with Staphylococcus aureus and Pseudomonas aeruginosa, and uninfected controls, were sampled at different timepoints of the infection. Peptides were extracted from the samples, followed by liquid chromatography tandem mass spectrometry analysis in data dependent acquisition mode. The resulting spectra and searched files have been deposited to online repositories and made easily accessible to enable further investigations of the infected and uninfected wound fluid peptidome.
ISSN:20524463
DOI:10.1038/s41597-025-05842-8