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Epidemiology of childhood constipation: a national study of Swedish children from 2006 to 2023

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Titel: Epidemiology of childhood constipation: a national study of Swedish children from 2006 to 2023
En epidemiologisk studie av förstoppning bland svenska barn från 2006 till 2023
Autoren: Kornfält Isberg, Helena, Falkenstein-Hagander, Kathy, Lenander, Cecilia, Derwig, Mariette, Hagander, Lars
Weitere Verfasser: Lund University, Faculty of Medicine, Department of Clinical Sciences, Malmö, Family Medicine and Community Medicine, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Malmö, Allmänmedicin och samhällsmedicin, Originator, Lund University, Faculty of Medicine, Department of Experimental Medical Science, Birgit Rausing Centre for Medical Humanities (BRCMH), Lunds universitet, Medicinska fakulteten, Institutionen för experimentell medicinsk vetenskap, Birgit Rausing Centrum för Medicinsk Humaniora (BRCMH), Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section V, Paediatrics (Lund), Pediatric surgery, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion V, Pediatrik, Lund, Barnkirurgi, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund, Section V, Paediatrics (Lund), Surgery and public health, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Lund, Sektion V, Pediatrik, Lund, Kirurgi och folkhälsa, Originator
Quelle: BMC Pediatrics. 25:1-7
Schlagwörter: Medical and Health Sciences, Clinical Medicine, Pediatrics, Medicin och hälsovetenskap, Klinisk medicin, Pediatrik
Beschreibung: Background: Childhood constipation is increasingly common, yet its prevalence is uncertain. This study examines comprehensive national data for trends in medically treated childhood constipation over a period of 18 years. Methods: Included were all Swedish children, 0-14 years, 2006-2023, and all prescriptions for constipation, using the national Swedish Prescribed Drug register. The primary outcome was the number of unique patients prescribed, presented by age, gender, year, county, and ATC-code. Univariate and multivariable linear regression with ecological data were assessed for associations with age, gender, and year of prescription. Results: The study population increased from 1.54 to 1.84 million children 0-14 years, while constipation increased more than sixfold, from 1.2% in 2006 to 7.9% in 2023. Children 0-4 years were prescribed the most, with an increase from 1.6 to 9.5%. Female gender was associated with 7.5 higher prescription frequency per 1000 inhabitants when adjusted for age and year (4.6-10.5 95%CI, p < 0.001). In 2023, girls aged 0-4 years were prescribed 27% more than boys (106.5 vs. 83.7 per 1000), compared with 23% among the 5-9-year-olds (86.8 vs. 70.6 per 1000), and 18% among the 10-14-year-olds (45.0 vs. 38.1 per 1000). Conclusions: Prescription of constipation drugs to children has increased remarkably during the past 18 years. This study highlights an escalating public health challenge among children, with considerable associated costs for family and society.
Background Childhood constipation is increasingly common, yet its prevalence is uncertain. This study examines comprehensive national data for trends in medically treated childhood constipation over a period of 18 years. Methods Included were all Swedish children, 0–14 years, 2006–2023, and all prescriptions for constipation, using the national Swedish Prescribed Drug register. The primary outcome was the number of unique patients prescribed, presented by age, gender, year, county, and ATC-code. Univariate and multivariable linear regression with ecological data were assessed for associations with age, gender, and year of prescription. Results The study population increased from 1.54 to 1.84 million children 0–14 years, while constipation increased more than sixfold, from 1.2% in 2006 to 7.9% in 2023. Children 0–4 years were prescribed the most, with an increase from 1.6 to 9.5%. Female gender was associated with 7.5 higher prescription frequency per 1000 inhabitants when adjusted for age and year (4.6–10.5 95%CI, p < 0.001). In 2023, girls aged 0–4 years were prescribed 27% more than boys (106.5 vs. 83.7 per 1000), compared with 23% among the 5–9-year-olds (86.8 vs. 70.6 per 1000), and 18% among the 10–14-year-olds (45.0 vs. 38.1 per 1000). Conclusions Prescription of constipation drugs to children has increased remarkably during the past 18 years. This study highlights an escalating public health challenge among children, with considerable associated costs for family and society.
Zugangs-URL: https://doi.org/10.1186/s12887-025-05858-4
Datenbank: SwePub
Beschreibung
Abstract:Background: Childhood constipation is increasingly common, yet its prevalence is uncertain. This study examines comprehensive national data for trends in medically treated childhood constipation over a period of 18 years. Methods: Included were all Swedish children, 0-14 years, 2006-2023, and all prescriptions for constipation, using the national Swedish Prescribed Drug register. The primary outcome was the number of unique patients prescribed, presented by age, gender, year, county, and ATC-code. Univariate and multivariable linear regression with ecological data were assessed for associations with age, gender, and year of prescription. Results: The study population increased from 1.54 to 1.84 million children 0-14 years, while constipation increased more than sixfold, from 1.2% in 2006 to 7.9% in 2023. Children 0-4 years were prescribed the most, with an increase from 1.6 to 9.5%. Female gender was associated with 7.5 higher prescription frequency per 1000 inhabitants when adjusted for age and year (4.6-10.5 95%CI, p < 0.001). In 2023, girls aged 0-4 years were prescribed 27% more than boys (106.5 vs. 83.7 per 1000), compared with 23% among the 5-9-year-olds (86.8 vs. 70.6 per 1000), and 18% among the 10-14-year-olds (45.0 vs. 38.1 per 1000). Conclusions: Prescription of constipation drugs to children has increased remarkably during the past 18 years. This study highlights an escalating public health challenge among children, with considerable associated costs for family and society.<br />Background Childhood constipation is increasingly common, yet its prevalence is uncertain. This study examines comprehensive national data for trends in medically treated childhood constipation over a period of 18 years. Methods Included were all Swedish children, 0–14 years, 2006–2023, and all prescriptions for constipation, using the national Swedish Prescribed Drug register. The primary outcome was the number of unique patients prescribed, presented by age, gender, year, county, and ATC-code. Univariate and multivariable linear regression with ecological data were assessed for associations with age, gender, and year of prescription. Results The study population increased from 1.54 to 1.84 million children 0–14 years, while constipation increased more than sixfold, from 1.2% in 2006 to 7.9% in 2023. Children 0–4 years were prescribed the most, with an increase from 1.6 to 9.5%. Female gender was associated with 7.5 higher prescription frequency per 1000 inhabitants when adjusted for age and year (4.6–10.5 95%CI, p < 0.001). In 2023, girls aged 0–4 years were prescribed 27% more than boys (106.5 vs. 83.7 per 1000), compared with 23% among the 5–9-year-olds (86.8 vs. 70.6 per 1000), and 18% among the 10–14-year-olds (45.0 vs. 38.1 per 1000). Conclusions Prescription of constipation drugs to children has increased remarkably during the past 18 years. This study highlights an escalating public health challenge among children, with considerable associated costs for family and society.
ISSN:14712431
DOI:10.1186/s12887-025-05858-4