Trabecular bone microstructure analysis on data from a novel twin robotic X-ray device
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| Název: | Trabecular bone microstructure analysis on data from a novel twin robotic X-ray device |
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| Autoři: | Klintström, E., Klintström, Benjamin, Spångeus, A., Sandborg, M., Woisetschläger, M. |
| Zdroj: | Acta Radiologica. 64(4):1566-1572 |
| Témata: | bone microstructure, imaging, osteoporosis, segmentation, Trabecular bone, Computerized tomography, Medical imaging, Microstructure, Imaging data, Mineral density, Strong correlation, Structural model indices, Structure parameter, Trabecular bones, TV models, Bone, Article, bone structure, bone volume, fracture, human, image analysis, image segmentation, micro-computed tomography, musculoskeletal system parameters, radius, robotics, structure analysis, structure model index, bone density, diagnostic imaging, procedures, robot assisted surgery, X ray, Bone and Bones, Cancellous Bone, Humans, Robotic Surgical Procedures, X-Ray Microtomography, X-Rays |
| Popis: | Background: Bone strength is related to both mineral density (BMD) and the bone microstructure. However, only the assessment of BMD is available in clinical routine care today. Purpose: To analyze and study the correlation of trabecular bone microstructure from the imaging data of a prototype Multitom Rax system, using micro-computed tomography (CT) data as the reference method (Skyscan 1176).Material and Methods: Imaging data from 14 bone samples from the human radius were analyzed regarding six bone structure parameters, i.e. trabecular nodes, separation, spacing, and thickness as well as bone volume (BV/TV) and structural model index (SMI).Results: All six structure parameters showed strong correlations to micro-CT with Spearman correlation coefficients in the range of 0.83–0.93. BV/TV and SMI had a correlation >0.90. Two of the parameters, namely, separation and number, had mean values in the same range as micro-CT. The other four were either over- or underestimated.Conclusion: The strong correlation between micro-CT and the clinical imaging system, indicates the possibility for analyzing bone microstructure with potential to add value in fracture assessment using the studied device in a clinical workflow. |
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| Přístupová URL adresa: | https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-329001 https://doi.org/10.1177/02841851221134973 |
| Databáze: | SwePub |
Nájsť tento článok vo Web of Science | Abstrakt: | Background: Bone strength is related to both mineral density (BMD) and the bone microstructure. However, only the assessment of BMD is available in clinical routine care today. Purpose: To analyze and study the correlation of trabecular bone microstructure from the imaging data of a prototype Multitom Rax system, using micro-computed tomography (CT) data as the reference method (Skyscan 1176).Material and Methods: Imaging data from 14 bone samples from the human radius were analyzed regarding six bone structure parameters, i.e. trabecular nodes, separation, spacing, and thickness as well as bone volume (BV/TV) and structural model index (SMI).Results: All six structure parameters showed strong correlations to micro-CT with Spearman correlation coefficients in the range of 0.83–0.93. BV/TV and SMI had a correlation >0.90. Two of the parameters, namely, separation and number, had mean values in the same range as micro-CT. The other four were either over- or underestimated.Conclusion: The strong correlation between micro-CT and the clinical imaging system, indicates the possibility for analyzing bone microstructure with potential to add value in fracture assessment using the studied device in a clinical workflow. |
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| ISSN: | 02841851 16000455 |
| DOI: | 10.1177/02841851221134973 |