Applications of recombinant proteins in cultured meat production

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Titel: Applications of recombinant proteins in cultured meat production
Autoren: Bárbara Flaibam, Gabriela Souza Alves, Esteban Ivan da Silva Vejar, Tatiana Barreto Rocha Nery, André Damasio, Rosana Goldbeck
Quelle: Future Foods, Vol 11, Iss , Pp 100582- (2025)
Verlagsinformationen: Elsevier, 2025.
Publikationsjahr: 2025
Bestand: LCC:Nutrition. Foods and food supply
LCC:Food processing and manufacture
Schlagwörter: Cellular agriculture, Cultivated meat, Culture media, Expression hosts, Precision fermentation, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456
Beschreibung: Cultured meat has emerged as a sustainable alternative to conventional animal protein sources, showing potential for addressing the food security challenges expected to arise in the coming decades. However, several obstacles still need to be overcome before cultured meat can be produced and commercialized on a large scale, including the development of serum-free culture media, the design of cell growth scaffolds, and the replication of sensory and nutritional attributes of conventional meat. Among these obstacles, the high cost of culture media and the dependence on animal-derived inputs produced in small volumes remain the most significant barriers to the upscaling of cultured meat, raising economic and ethical concerns. A promising solution to these challenges is precision fermentation, whereby microorganisms are used as ''cell factories'' to produce specific recombinant proteins and molecules that can be incorporated into culture media or final products. Recombinant proteins can reduce production costs and improve the sensory and nutritional characteristics of cultured meat, resolving the ethical and environmental concerns associated with traditional meat production. This review examines the potential of applying recombinant proteins to solve challenges associated with cultured meat processing.
Publikationsart: article
Dateibeschreibung: electronic resource
Sprache: English
ISSN: 2666-8335
Relation: http://www.sciencedirect.com/science/article/pii/S2666833525000450; https://doaj.org/toc/2666-8335
DOI: 10.1016/j.fufo.2025.100582
Zugangs-URL: https://doaj.org/article/87810ff7c8974e3a8b0d537e8aad5b8d
Dokumentencode: edsdoj.87810ff7c8974e3a8b0d537e8aad5b8d
Datenbank: Directory of Open Access Journals
Beschreibung
Abstract:Cultured meat has emerged as a sustainable alternative to conventional animal protein sources, showing potential for addressing the food security challenges expected to arise in the coming decades. However, several obstacles still need to be overcome before cultured meat can be produced and commercialized on a large scale, including the development of serum-free culture media, the design of cell growth scaffolds, and the replication of sensory and nutritional attributes of conventional meat. Among these obstacles, the high cost of culture media and the dependence on animal-derived inputs produced in small volumes remain the most significant barriers to the upscaling of cultured meat, raising economic and ethical concerns. A promising solution to these challenges is precision fermentation, whereby microorganisms are used as ''cell factories'' to produce specific recombinant proteins and molecules that can be incorporated into culture media or final products. Recombinant proteins can reduce production costs and improve the sensory and nutritional characteristics of cultured meat, resolving the ethical and environmental concerns associated with traditional meat production. This review examines the potential of applying recombinant proteins to solve challenges associated with cultured meat processing.
ISSN:26668335
DOI:10.1016/j.fufo.2025.100582