Zobrazit v EDS

Initial orthostatic hypotension and orthostatic intolerance symptom prevalence in older adults: A systematic review

Uloženo v:
Podrobná bibliografie
Název: Initial orthostatic hypotension and orthostatic intolerance symptom prevalence in older adults: A systematic review
Autoři: Elena M. Christopoulos, Jennifer Tran, Sarah L. Hillebrand, Peter W. Lange, Rebecca K. Iseli, Carel G.M. Meskers, Andrea B. Maier
Zdroj: International Journal of Cardiology. Hypertension, Vol 8, Iss , Pp 100071- (2021)
Informace o vydavateli: Elsevier, 2021.
Rok vydání: 2021
Sbírka: LCC:Diseases of the circulatory (Cardiovascular) system
Témata: Hypotension, Orthostatic intolerance, Symptoms, Blood pressure, Syncope, Frail elderly, Diseases of the circulatory (Cardiovascular) system, RC666-701
Popis: Background: Initial orthostatic hypotension is a clinically relevant syndrome in older adults which has been associated with symptoms of orthostatic intolerance. The aim of this systematic review was to determine the prevalence of orthostatic intolerance symptoms in older adults with initial orthostatic hypotension. Methods: MEDLINE (from 1946), EMBASE (from 1974) and Cochrane were searched to December 6th, 2019 using the terms “initial orthostatic hypotension”, “postural hypotension” and “older adults”. Study selection involved the following criteria: published in English; mean or median age ≥65 years and diagnosis of initial orthostatic hypotension encompassed a decrease in systolic blood pressure by ≥ 40 mmHg and/or diastolic blood pressure by ≥ 20 mmHg within a maximum of 1 min following a postural change. Results: Of 8311 articles, 12 articles reporting initial orthostatic hypotension prevalence in 3446 participants with a mean age of 75 (6 SD) years (56.5% female) were included. Five initial orthostatic hypotension definition variations were utilised and symptoms were reported in six articles (968 participants, mean age 73.4 (6.1 SD) years, 56% female). The prevalence of symptoms in older adults with initial orthostatic hypotension ranged from 24 to 100% and was dependent on variations in timing or the inclusion of symptoms in the initial orthostatic hypotension definition. Conclusions: Where orthostatic intolerance symptoms were reported, a large proportion of older adults with a diagnosis of initial orthostatic hypotension were symptomatic. However, the literature on initial orthostatic hypotension and orthostatic intolerance symptoms is scarce and a variety of definitions of initial orthostatic hypotension are utilised.
Druh dokumentu: article
Popis souboru: electronic resource
Jazyk: English
ISSN: 2590-0862
Relation: http://www.sciencedirect.com/science/article/pii/S2590086220300483; https://doaj.org/toc/2590-0862
DOI: 10.1016/j.ijchy.2020.100071
Přístupová URL adresa: https://doaj.org/article/1f92be369ca1467e95d2fe451b4e6eb0
Přístupové číslo: edsdoj.1f92be369ca1467e95d2fe451b4e6eb0
Databáze: Directory of Open Access Journals
Popis
Abstrakt:Background: Initial orthostatic hypotension is a clinically relevant syndrome in older adults which has been associated with symptoms of orthostatic intolerance. The aim of this systematic review was to determine the prevalence of orthostatic intolerance symptoms in older adults with initial orthostatic hypotension. Methods: MEDLINE (from 1946), EMBASE (from 1974) and Cochrane were searched to December 6th, 2019 using the terms “initial orthostatic hypotension”, “postural hypotension” and “older adults”. Study selection involved the following criteria: published in English; mean or median age ≥65 years and diagnosis of initial orthostatic hypotension encompassed a decrease in systolic blood pressure by ≥ 40 mmHg and/or diastolic blood pressure by ≥ 20 mmHg within a maximum of 1 min following a postural change. Results: Of 8311 articles, 12 articles reporting initial orthostatic hypotension prevalence in 3446 participants with a mean age of 75 (6 SD) years (56.5% female) were included. Five initial orthostatic hypotension definition variations were utilised and symptoms were reported in six articles (968 participants, mean age 73.4 (6.1 SD) years, 56% female). The prevalence of symptoms in older adults with initial orthostatic hypotension ranged from 24 to 100% and was dependent on variations in timing or the inclusion of symptoms in the initial orthostatic hypotension definition. Conclusions: Where orthostatic intolerance symptoms were reported, a large proportion of older adults with a diagnosis of initial orthostatic hypotension were symptomatic. However, the literature on initial orthostatic hypotension and orthostatic intolerance symptoms is scarce and a variety of definitions of initial orthostatic hypotension are utilised.
ISSN:25900862
DOI:10.1016/j.ijchy.2020.100071