IMPACT OF PAPILLOMAVIRUS INFECTION ON WOMEN'S REPRODUCTIVE HEALTH AND PERINATAL OUTCOMES

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Bibliographic Details
Title: IMPACT OF PAPILLOMAVIRUS INFECTION ON WOMEN'S REPRODUCTIVE HEALTH AND PERINATAL OUTCOMES
Authors: Елена Николаевна Кравченко, Лариса Владимировна Куклина, Руслан Альбертович Каримов
Source: Мать и дитя в Кузбассе, Vol 26, Iss 3, Pp 53-59 (2025)
Publisher Information: The Publishing House Medicine and Enlightenment, 2025.
Publication Year: 2025
Collection: LCC:Pediatrics
LCC:Gynecology and obstetrics
Subject Terms: папилломавирусная инфекция и репродуктивное здоровье, папилломавирусная инфекция у беременных, Pediatrics, RJ1-570, Gynecology and obstetrics, RG1-991
Description: The literature review is devoted to the current problem concerning papillomavirus infection (PVI) in pregnant women. PVI, being one of the current problems of modern medicine, requires an interdisciplinary approach in diagnostics and management tactics, including in pregnant women. Human papillomavirus (HPV) infection affects reproductive health and perinatal outcomes. One of the most serious obstetric complications associated with HPV is fetal growth retardation, the pathogenesis of which can be mediated by direct viral effects on the trophoblast and endothelium of placental vessels. There is evidence of the proinflammatory effect of the virus and its ability to potentiate the systemic inflammatory response in the fetoplacental complex, clinically manifested in chorioamnionitis. With PVI, the number of premature births, premature rupture of membranes, and antenatal death of the fetus increases. Giant pointed condylomas in pregnant women create mechanical obstacles to vaginal delivery and are associated with the risk of vertical transmission of the virus, the development of recurrent respiratory papillomatosis in the infant.
Document Type: article
File Description: electronic resource
Language: Russian
ISSN: 1991-010X
2542-0968
Relation: https://mednauki.ru/index.php/MD/article/view/1252; https://doaj.org/toc/1991-010X; https://doaj.org/toc/2542-0968
Access URL: https://doaj.org/article/1320ec0c851a40a6a3f28f74c0828123
Accession Number: edsdoj.1320ec0c851a40a6a3f28f74c0828123
Database: Directory of Open Access Journals
Description
Abstract:The literature review is devoted to the current problem concerning papillomavirus infection (PVI) in pregnant women. PVI, being one of the current problems of modern medicine, requires an interdisciplinary approach in diagnostics and management tactics, including in pregnant women. Human papillomavirus (HPV) infection affects reproductive health and perinatal outcomes. One of the most serious obstetric complications associated with HPV is fetal growth retardation, the pathogenesis of which can be mediated by direct viral effects on the trophoblast and endothelium of placental vessels. There is evidence of the proinflammatory effect of the virus and its ability to potentiate the systemic inflammatory response in the fetoplacental complex, clinically manifested in chorioamnionitis. With PVI, the number of premature births, premature rupture of membranes, and antenatal death of the fetus increases. Giant pointed condylomas in pregnant women create mechanical obstacles to vaginal delivery and are associated with the risk of vertical transmission of the virus, the development of recurrent respiratory papillomatosis in the infant.
ISSN:1991010X
25420968