An LC/DAD-UV/MS method for the rapid detection of aristolochic acid in plant preparations.
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| Název: | An LC/DAD-UV/MS method for the rapid detection of aristolochic acid in plant preparations. |
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| Autoři: | Ioset, J.R., Raoelison, G.E., Hostettmann, K. |
| Rok vydání: | 2025 |
| Sbírka: | Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
| Témata: | Aristolochia, Aristolochic Acids/chemistry, Aristolochic Acids/isolation & purification, Chromatography/methods, Chromatography, Liquid/methods, Thin Layer/methods, Mass Spectrometry/methods, Molecular Structure, Plant Extracts/chemistry, Plant Extracts/isolation & purification, Plant Leaves/chemistry, Plant Stems/chemistry, Ultraviolet Rays |
| Popis: | A new method using direct on-line coupling between HPLC and UV-DAD/MS was developed for the rapid detection of aristolochic acid I in plant preparations. The use of both UV-DAD and MS detectors enables this method to be very selective. A ng range detection limit was determined for both UV and MS detections. A quantitative determination of aristolochic acid I in plant preparations was achieved using UV and MS detection. A thin layer chromatography assay was also developed for the preliminary detection of aristolochic acid I in complex mixtures. |
| Druh dokumentu: | article in journal/newspaper |
| Jazyk: | English |
| ISSN: | 0032-0943 |
| Relation: | Planta Medica: Journal of Medicinal Plant and Natural Product Research; https://iris.unil.ch/handle/iris/44859; serval:BIB_23311; 000178627300025 |
| DOI: | 10.1055/s-2002-34413 |
| Dostupnost: | https://iris.unil.ch/handle/iris/44859 https://doi.org/10.1055/s-2002-34413 |
| Přístupové číslo: | edsbas.D25429EA |
| Databáze: | BASE |
Nájsť tento článok vo Web of Science | Abstrakt: | A new method using direct on-line coupling between HPLC and UV-DAD/MS was developed for the rapid detection of aristolochic acid I in plant preparations. The use of both UV-DAD and MS detectors enables this method to be very selective. A ng range detection limit was determined for both UV and MS detections. A quantitative determination of aristolochic acid I in plant preparations was achieved using UV and MS detection. A thin layer chromatography assay was also developed for the preliminary detection of aristolochic acid I in complex mixtures. |
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| ISSN: | 00320943 |
| DOI: | 10.1055/s-2002-34413 |