Zobrazit v EDS

The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study.

Uloženo v:
Podrobná bibliografie
Název: The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study.
Autoři: Feller, A., Matthes, K.L., Bordoni, A., Bouchardy, C., Bulliard, J.L., Herrmann, C., Konzelmann, I., Maspoli, M., Mousavi, M., Rohrmann, S., Staehelin, K., Arndt, V.
Přispěvatelé: NICER Working Group
Rok vydání: 2025
Sbírka: Université de Lausanne (UNIL): Serval - Serveur académique lausannois
Témata: Adolescent, Adult, Aged, Alcohol Drinking/adverse effects, Cancer Survivors/statistics & numerical data, Female, Humans, Incidence, Male, Middle Aged, Neoplasms/complications, Neoplasms/therapy, Neoplasms, Second Primary/epidemiology, Second Primary/etiology, Second Primary/pathology, Registries, Retrospective Studies, Risk Factors, Smoking/adverse effects, Switzerland/epidemiology, Young Adult, Cohort study, Relative risk, Retrospective, Second primary cancer, Switzerland
Popis: More people than ever before are currently living with a diagnosis of cancer and the number of people concerned is likely to continue to rise. Cancer survivors are at risk of developing a second primary cancer (SPC). This study aims to investigate the risk of SPC in Switzerland. The study cohort included all patients with a first primary cancer recorded in 9 Swiss population-based cancer registries 1981-2009 who had a minimum survival of 6 months, and a potential follow-up until the end of 2014. We calculated standardized incidence ratios (SIR) to estimate relative risks (RR) of SPC in cancer survivors compared with the cancer risk of the general population. SIR were stratified by type of first cancer, sex, age and period of first diagnosis, survival period and site of SPC. A total of 33,793 SPC were observed in 310,113 cancer patients. Both male (SIR 1.18, 95%CI 1.16-1.19) and female (SIR 1.20, 95%CI 1.18-1.22) cancer survivors had an elevated risk of developing a SPC. Risk estimates varied substantially according to type of first cancer and were highest in patients initially diagnosed with cancer of the oral cavity and pharynx, Hodgkin lymphoma, laryngeal, oesophageal, or lung cancer. Age-stratified analyses revealed a tendency towards higher RR in patients first diagnosed at younger ages. Stratified by survival period, risk estimates showed a rising trend with increasing time from the initial diagnosis. We observed strong associations between particular types of first and SPC, i.e. cancer types sharing common risk factors such as smoking or alcohol consumption (e.g. repeated cancer of the oral cavity and pharynx (SIR males 20.12, 95%CI 17.91-22.33; SIR females 37.87, 95%CI 30.27-45.48). Swiss cancer survivors have an increased risk of developing a SPC compared to the general population, particularly patients first diagnosed before age 50 and those surviving more than 10 years. Cancer patients should remain under continued surveillance not only for recurrent cancers but also for new cancers. Some first and ...
Druh dokumentu: article in journal/newspaper
Popis souboru: application/pdf
Jazyk: English
ISSN: 1471-2407
Relation: BMC Cancer; https://iris.unil.ch/handle/iris/66180; serval:BIB_309F3E21A26F; 000513588000001
DOI: 10.1186/s12885-019-6452-0
Dostupnost: https://iris.unil.ch/handle/iris/66180
https://doi.org/10.1186/s12885-019-6452-0
Přístupové číslo: edsbas.C13E4F67
Databáze: BASE
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://iris.unil.ch/handle/iris/66180#
    Name: EDS - BASE (s4221598)
    Category: fullText
    Text: View record from BASE
  – Url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pmc&term=1471-2407[TA]+AND+[PG]+AND+2025[PDAT]
    Name: FREE - PubMed Central (ISSN based link)
    Category: fullText
    Text: Full Text
    Icon: https://imageserver.ebscohost.com/NetImages/iconPdf.gif
    MouseOverText: Check this PubMed for the article full text.
  – Url: https://resolver.ebscohost.com/openurl?sid=EBSCO:edsbas&genre=article&issn=14712407&ISBN=&volume=&issue=&date=20250101&spage=&pages=&title=The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study.&atitle=The%20relative%20risk%20of%20second%20primary%20cancers%20in%20Switzerland%3A%20a%20population-based%20retrospective%20cohort%20study.&aulast=Feller%2C%20A.&id=DOI:10.1186/s12885-019-6452-0
    Name: Full Text Finder
    Category: fullText
    Text: Full Text Finder
    Icon: https://imageserver.ebscohost.com/branding/images/FTF.gif
    MouseOverText: Full Text Finder
  – Url: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=EBSCO&SrcAuth=EBSCO&DestApp=WOS&ServiceName=TransferToWoS&DestLinkType=GeneralSearchSummary&Func=Links&author=Feller%20A
    Name: ISI
    Category: fullText
    Text: Nájsť tento článok vo Web of Science
    Icon: https://imagesrvr.epnet.com/ls/20docs.gif
    MouseOverText: Nájsť tento článok vo Web of Science
Header DbId: edsbas
DbLabel: BASE
An: edsbas.C13E4F67
RelevancyScore: 939
AccessLevel: 3
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 939.3056640625
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Feller%2C+A%2E%22">Feller, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Matthes%2C+K%2EL%2E%22">Matthes, K.L.</searchLink><br /><searchLink fieldCode="AR" term="%22Bordoni%2C+A%2E%22">Bordoni, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Bouchardy%2C+C%2E%22">Bouchardy, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Bulliard%2C+J%2EL%2E%22">Bulliard, J.L.</searchLink><br /><searchLink fieldCode="AR" term="%22Herrmann%2C+C%2E%22">Herrmann, C.</searchLink><br /><searchLink fieldCode="AR" term="%22Konzelmann%2C+I%2E%22">Konzelmann, I.</searchLink><br /><searchLink fieldCode="AR" term="%22Maspoli%2C+M%2E%22">Maspoli, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Mousavi%2C+M%2E%22">Mousavi, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Rohrmann%2C+S%2E%22">Rohrmann, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Staehelin%2C+K%2E%22">Staehelin, K.</searchLink><br /><searchLink fieldCode="AR" term="%22Arndt%2C+V%2E%22">Arndt, V.</searchLink>
– Name: Author
  Label: Contributors
  Group: Au
  Data: NICER Working Group
– Name: DatePubCY
  Label: Publication Year
  Group: Date
  Data: 2025
– Name: Subset
  Label: Collection
  Group: HoldingsInfo
  Data: Université de Lausanne (UNIL): Serval - Serveur académique lausannois
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Adolescent%22">Adolescent</searchLink><br /><searchLink fieldCode="DE" term="%22Adult%22">Adult</searchLink><br /><searchLink fieldCode="DE" term="%22Aged%22">Aged</searchLink><br /><searchLink fieldCode="DE" term="%22Alcohol+Drinking%2Fadverse+effects%22">Alcohol Drinking/adverse effects</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+Survivors%2Fstatistics+%26+numerical+data%22">Cancer Survivors/statistics & numerical data</searchLink><br /><searchLink fieldCode="DE" term="%22Female%22">Female</searchLink><br /><searchLink fieldCode="DE" term="%22Humans%22">Humans</searchLink><br /><searchLink fieldCode="DE" term="%22Incidence%22">Incidence</searchLink><br /><searchLink fieldCode="DE" term="%22Male%22">Male</searchLink><br /><searchLink fieldCode="DE" term="%22Middle+Aged%22">Middle Aged</searchLink><br /><searchLink fieldCode="DE" term="%22Neoplasms%2Fcomplications%22">Neoplasms/complications</searchLink><br /><searchLink fieldCode="DE" term="%22Neoplasms%2Ftherapy%22">Neoplasms/therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Neoplasms%22">Neoplasms</searchLink><br /><searchLink fieldCode="DE" term="%22Second+Primary%2Fepidemiology%22">Second Primary/epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22Second+Primary%2Fetiology%22">Second Primary/etiology</searchLink><br /><searchLink fieldCode="DE" term="%22Second+Primary%2Fpathology%22">Second Primary/pathology</searchLink><br /><searchLink fieldCode="DE" term="%22Registries%22">Registries</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective+Studies%22">Retrospective Studies</searchLink><br /><searchLink fieldCode="DE" term="%22Risk+Factors%22">Risk Factors</searchLink><br /><searchLink fieldCode="DE" term="%22Smoking%2Fadverse+effects%22">Smoking/adverse effects</searchLink><br /><searchLink fieldCode="DE" term="%22Switzerland%2Fepidemiology%22">Switzerland/epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22Young+Adult%22">Young Adult</searchLink><br /><searchLink fieldCode="DE" term="%22Cohort+study%22">Cohort study</searchLink><br /><searchLink fieldCode="DE" term="%22Relative+risk%22">Relative risk</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective%22">Retrospective</searchLink><br /><searchLink fieldCode="DE" term="%22Second+primary+cancer%22">Second primary cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Switzerland%22">Switzerland</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: More people than ever before are currently living with a diagnosis of cancer and the number of people concerned is likely to continue to rise. Cancer survivors are at risk of developing a second primary cancer (SPC). This study aims to investigate the risk of SPC in Switzerland. The study cohort included all patients with a first primary cancer recorded in 9 Swiss population-based cancer registries 1981-2009 who had a minimum survival of 6 months, and a potential follow-up until the end of 2014. We calculated standardized incidence ratios (SIR) to estimate relative risks (RR) of SPC in cancer survivors compared with the cancer risk of the general population. SIR were stratified by type of first cancer, sex, age and period of first diagnosis, survival period and site of SPC. A total of 33,793 SPC were observed in 310,113 cancer patients. Both male (SIR 1.18, 95%CI 1.16-1.19) and female (SIR 1.20, 95%CI 1.18-1.22) cancer survivors had an elevated risk of developing a SPC. Risk estimates varied substantially according to type of first cancer and were highest in patients initially diagnosed with cancer of the oral cavity and pharynx, Hodgkin lymphoma, laryngeal, oesophageal, or lung cancer. Age-stratified analyses revealed a tendency towards higher RR in patients first diagnosed at younger ages. Stratified by survival period, risk estimates showed a rising trend with increasing time from the initial diagnosis. We observed strong associations between particular types of first and SPC, i.e. cancer types sharing common risk factors such as smoking or alcohol consumption (e.g. repeated cancer of the oral cavity and pharynx (SIR males 20.12, 95%CI 17.91-22.33; SIR females 37.87, 95%CI 30.27-45.48). Swiss cancer survivors have an increased risk of developing a SPC compared to the general population, particularly patients first diagnosed before age 50 and those surviving more than 10 years. Cancer patients should remain under continued surveillance not only for recurrent cancers but also for new cancers. Some first and ...
– Name: TypeDocument
  Label: Document Type
  Group: TypDoc
  Data: article in journal/newspaper
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: application/pdf
– Name: Language
  Label: Language
  Group: Lang
  Data: English
– Name: ISSN
  Label: ISSN
  Group: ISSN
  Data: 1471-2407
– Name: NoteTitleSource
  Label: Relation
  Group: SrcInfo
  Data: BMC Cancer; https://iris.unil.ch/handle/iris/66180; serval:BIB_309F3E21A26F; 000513588000001
– Name: DOI
  Label: DOI
  Group: ID
  Data: 10.1186/s12885-019-6452-0
– Name: URL
  Label: Availability
  Group: URL
  Data: https://iris.unil.ch/handle/iris/66180<br />https://doi.org/10.1186/s12885-019-6452-0
– Name: AN
  Label: Accession Number
  Group: ID
  Data: edsbas.C13E4F67
PLink https://erproxy.cvtisr.sk/sfx/access?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsbas&AN=edsbas.C13E4F67
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1186/s12885-019-6452-0
    Languages:
      – Text: English
    Subjects:
      – SubjectFull: Adolescent
        Type: general
      – SubjectFull: Adult
        Type: general
      – SubjectFull: Aged
        Type: general
      – SubjectFull: Alcohol Drinking/adverse effects
        Type: general
      – SubjectFull: Cancer Survivors/statistics & numerical data
        Type: general
      – SubjectFull: Female
        Type: general
      – SubjectFull: Humans
        Type: general
      – SubjectFull: Incidence
        Type: general
      – SubjectFull: Male
        Type: general
      – SubjectFull: Middle Aged
        Type: general
      – SubjectFull: Neoplasms/complications
        Type: general
      – SubjectFull: Neoplasms/therapy
        Type: general
      – SubjectFull: Neoplasms
        Type: general
      – SubjectFull: Second Primary/epidemiology
        Type: general
      – SubjectFull: Second Primary/etiology
        Type: general
      – SubjectFull: Second Primary/pathology
        Type: general
      – SubjectFull: Registries
        Type: general
      – SubjectFull: Retrospective Studies
        Type: general
      – SubjectFull: Risk Factors
        Type: general
      – SubjectFull: Smoking/adverse effects
        Type: general
      – SubjectFull: Switzerland/epidemiology
        Type: general
      – SubjectFull: Young Adult
        Type: general
      – SubjectFull: Cohort study
        Type: general
      – SubjectFull: Relative risk
        Type: general
      – SubjectFull: Retrospective
        Type: general
      – SubjectFull: Second primary cancer
        Type: general
      – SubjectFull: Switzerland
        Type: general
    Titles:
      – TitleFull: The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Feller, A.
      – PersonEntity:
          Name:
            NameFull: Matthes, K.L.
      – PersonEntity:
          Name:
            NameFull: Bordoni, A.
      – PersonEntity:
          Name:
            NameFull: Bouchardy, C.
      – PersonEntity:
          Name:
            NameFull: Bulliard, J.L.
      – PersonEntity:
          Name:
            NameFull: Herrmann, C.
      – PersonEntity:
          Name:
            NameFull: Konzelmann, I.
      – PersonEntity:
          Name:
            NameFull: Maspoli, M.
      – PersonEntity:
          Name:
            NameFull: Mousavi, M.
      – PersonEntity:
          Name:
            NameFull: Rohrmann, S.
      – PersonEntity:
          Name:
            NameFull: Staehelin, K.
      – PersonEntity:
          Name:
            NameFull: Arndt, V.
      – PersonEntity:
          Name:
            NameFull: NICER Working Group
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 14712407
            – Type: issn-locals
              Value: edsbas
ResultId 1