Simplified calculation methods produce inaccurate signals.
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| Title: | Simplified calculation methods produce inaccurate signals. |
|---|---|
| Authors: | Joseph James Tharayil, Jorge Blanco Alonso, Silvia Farcito, Bryn Lloyd, Armando Romani, Elvis Boci, Antonino Cassara, Felix Schürmann, Esra Neufeld, Niels Kuster, Michael Reimann |
| Publication Year: | 2025 |
| Subject Terms: | Biophysics, Cell Biology, Genetics, Neuroscience, Physiology, Biotechnology, Evolutionary Biology, Developmental Biology, Cancer, Space Science, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, standalone python code, sonata data format, rat somatosensory cortex, new avenues open, network simulations accessible, coreneuron computation engine, computational neuroscience grows, complex tissue anatomy, permit online calculation, signal information content, e ., non, simulate eeg recordings, enable efficient calculation, div >< p, dipolar current sources |
| Description: | EEG (A), ECoG (B), and LFP (C) signals, recorded over, or within, the somatosensory cortex, calculated with the point-source and line-source approximation, with the generalized reciprocity theorem (ground truth), and with the simplified dipole-based approaches. D-F: Contribution of each region to EEG, ECoG, and LFP signals, respectively. Solid lines indicate general reciprocity approach, dashed lines indicate dipole approach. G-I: Weights for EEG, ECoG, and LFP recordings, respectively, calculated using the reciprocity approach, for a sample of L5 pyramidal cells in the forelimb (compartments represented as circles), hindlimb (compartments represented as triangles, and enclosed in pink box) and upper lip (compartments represented as squares, and enclosed in red box) regions. Electrodes are represented as red circles. Note the varying color scale ranges. J-L: As in G-I, but calculated using the dipole approach |
| Document Type: | still image |
| Language: | unknown |
| Relation: | https://figshare.com/articles/figure/Simplified_calculation_methods_produce_inaccurate_signals_/29138127 |
| DOI: | 10.1371/journal.pcbi.1013023.g005 |
| Availability: | https://doi.org/10.1371/journal.pcbi.1013023.g005 https://figshare.com/articles/figure/Simplified_calculation_methods_produce_inaccurate_signals_/29138127 |
| Rights: | CC BY 4.0 |
| Accession Number: | edsbas.B29C0A10 |
| Database: | BASE |
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