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Clinical significance of determining neutrophil extracellular traps in women with oncogynecological neoplasms ; Клиническое значение определения внеклеточных ловушек нейтрофилов у женщин с онкогинекологическими заболеваниями

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Title:	Clinical significance of determining neutrophil extracellular traps in women with oncogynecological neoplasms ; Клиническое значение определения внеклеточных ловушек нейтрофилов у женщин с онкогинекологическими заболеваниями
Authors:	Z. D. Aslanova, J. Kh. Khizroeva, A. G. Solopova, V. A. Solodkiy, A. V. Vorobev, D. V. Blinov, M. D. Aslanova, I. A. Nakaidze, J.-C. Gris, I. Elalamy, A. D. Makatsariya, З. Д. Асланова, Д. Х. Хизроева, А. Г. Солопова, В. А. Солодкий, А. В. Воробьев, Д. В. Блинов, М. Д. Асланова, И. А. Накаидзе, Ж.-К. Гри, И. Элалами, А. Д. Макацария
Source:	Obstetrics, Gynecology and Reproduction; Vol 17, No 6 (2023); 751-768 ; Акушерство, Гинекология и Репродукция; Vol 17, No 6 (2023); 751-768 ; 2500-3194 ; 2313-7347
Publisher Information:	IRBIS LLC
Publication Year:	2024
Collection:	Obstetrics, Gynecology and Reproduction (AGR - E-Journal) / Акушерство, Гинекология и Репродукция (АГР)
Subject Terms:	онкологические заболевания, NETs, NETosis, myeloperoxidase, citrullinated histone H3, cancer, oncological diseases, нетоз, миелопероксидаза, цитруллинированный гистон H3, рак
Description:	The formation of neutrophil extracellular traps (NETs), described first in 2004 as a previously unknown neutrophil strategy for combating microbes, has been attracting a growing interest in research community. NETs play a key role in inflammation and infection exploiting effector functions such as degranulation, phagocytosis as well as production of reactive oxygen species (ROS). NETs play a crucial role in defense against systemic infections. Additionally NETs involved in inflammation, and in the pathogenesis of non-infectious diseases, such as autoimmune diseases and cancer. ; Образование внеклеточных ловушек нейтрофилов (англ. neutrophil extracellular traps, NETs), впервые описанное в 2004 г. как ранее неизвестная стратегия нейтрофилов для борьбы с микробами, привлекает растущий интерес в исследовательском сообществе. NETs выполняют ключевую роль в воспалении и инфекции, где они используют такие эффекторные функции, как дегрануляция, фагоцитоз, образование активных форм кислорода (англ. reactive oxygen species, ROS). NETs играют решающую роль в реализации защитно-приспособительных процессов, таких как воспаление, и патогенезе неинфекционных заболеваний, таких как аутоиммунные заболевания и рак.
Document Type:	article in journal/newspaper
File Description:	application/pdf
Language:	Russian
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DOI:	10.17749/2313-7347/ob.gyn.rep.2023.447
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Abstract:	The formation of neutrophil extracellular traps (NETs), described first in 2004 as a previously unknown neutrophil strategy for combating microbes, has been attracting a growing interest in research community. NETs play a key role in inflammation and infection exploiting effector functions such as degranulation, phagocytosis as well as production of reactive oxygen species (ROS). NETs play a crucial role in defense against systemic infections. Additionally NETs involved in inflammation, and in the pathogenesis of non-infectious diseases, such as autoimmune diseases and cancer. ; Образование внеклеточных ловушек нейтрофилов (англ. neutrophil extracellular traps, NETs), впервые описанное в 2004 г. как ранее неизвестная стратегия нейтрофилов для борьбы с микробами, привлекает растущий интерес в исследовательском сообществе. NETs выполняют ключевую роль в воспалении и инфекции, где они используют такие эффекторные функции, как дегрануляция, фагоцитоз, образование активных форм кислорода (англ. reactive oxygen species, ROS). NETs играют решающую роль в реализации защитно-приспособительных процессов, таких как воспаление, и патогенезе неинфекционных заболеваний, таких как аутоиммунные заболевания и рак.
DOI:	10.17749/2313-7347/ob.gyn.rep.2023.447