Sustainability of a Three-Species Predator–Prey Model in Tumor-Immune Dynamics with Periodic Treatment

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Názov: Sustainability of a Three-Species Predator–Prey Model in Tumor-Immune Dynamics with Periodic Treatment
Autori: Avan Al-Saffar, Eun-jin Kim
Zdroj: Entropy ; Volume 27 ; Issue 3 ; Pages: 264
Informácie o vydavateľovi: Multidisciplinary Digital Publishing Institute
Rok vydania: 2025
Zbierka: MDPI Open Access Publishing
Predmety: dynamical systems, sustainability, fisher information, perturbations, probability density function (PDF)
Popis: Using a tumor-immune growth model, we investigate how immunotherapy affects its dynamical characteristics. Specifically, we extend the prey–predator model of tumor cells and immune cells by including periodic immunotherapy, the nonlinear damping of cancer cells, and the dynamics of a healthy cell population, and investigate the effects of the model parameters. The ideal value of immunotherapy, which promotes the growth of immune (and healthy) cells while contributing to the elimination or control of the cancer cells, is determined by using Fisher information as a measure of variability throughout our study.
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Jazyk: English
Relation: Multidisciplinary Applications; https://dx.doi.org/10.3390/e27030264
DOI: 10.3390/e27030264
Dostupnosť: https://doi.org/10.3390/e27030264
Rights: https://creativecommons.org/licenses/by/4.0/
Prístupové číslo: edsbas.30E8A777
Databáza: BASE
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  Data: Sustainability of a Three-Species Predator–Prey Model in Tumor-Immune Dynamics with Periodic Treatment
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  Data: <searchLink fieldCode="AR" term="%22Avan+Al-Saffar%22">Avan Al-Saffar</searchLink><br /><searchLink fieldCode="AR" term="%22Eun-jin+Kim%22">Eun-jin Kim</searchLink>
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  Data: Entropy ; Volume 27 ; Issue 3 ; Pages: 264
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  Data: Using a tumor-immune growth model, we investigate how immunotherapy affects its dynamical characteristics. Specifically, we extend the prey–predator model of tumor cells and immune cells by including periodic immunotherapy, the nonlinear damping of cancer cells, and the dynamics of a healthy cell population, and investigate the effects of the model parameters. The ideal value of immunotherapy, which promotes the growth of immune (and healthy) cells while contributing to the elimination or control of the cancer cells, is determined by using Fisher information as a measure of variability throughout our study.
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