Fibrosierte Hypersensitivitätspneumonie: Fokus auf pathologierelevante Aspekte der neuen klinischen Leitlinie der ATS/JRS/ALAT zur Diagnostik der Hypersensitivitätspneumonie bei Erwachsenen [Fibrotic hypersensitivity pneumonia: focus on pathology-relevant aspects of the new ATS/JRS/ALAT clinical guideline for the diagnosis of hypersensitivity pneumonia in adults]

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Title: Fibrosierte Hypersensitivitätspneumonie: Fokus auf pathologierelevante Aspekte der neuen klinischen Leitlinie der ATS/JRS/ALAT zur Diagnostik der Hypersensitivitätspneumonie bei Erwachsenen [Fibrotic hypersensitivity pneumonia: focus on pathology-relevant aspects of the new ATS/JRS/ALAT clinical guideline for the diagnosis of hypersensitivity pneumonia in adults]
Authors: Berezowska, S.
Source: Der Pathologe, vol. 42, no. 1, pp. 48-54
Publisher Information: 2021.
Publication Year: 2021
Subject Terms: Adult, Alveolitis, Extrinsic Allergic/diagnosis, Humans, Idiopathic Pulmonary Fibrosis/diagnosis, Lung, Lung Diseases, Interstitial/diagnosis, Pneumonia, Radiography, Chronic fibrotic lung disease, Exogenous allergic alveolitis, Granuloma, Hypersensitivity pneumonitis, Idiopathic interstitial Pneumonia, 3. Good health
Description: Hypersensitivity pneumonia (HP), also called exogenous allergic alveolitis, is a chronic interstitial pneumonia induced by a hypersensitivity reaction to an identified or unidentified antigen in exposed and susceptible individuals that may progress to terminal lung fibrosis. The diagnosis of HP presents a diagnostic challenge. Though therapeutically important, it may be particularly difficult to differentiate fibrotic HP, historically termed chronic HP, from idiopathic pulmonary fibrosis (IPF) or interstitial lung disease associated with connective tissue diseases (CTD-ILD). Multidisciplinary discussion and thus a synoptic evaluation of all findings is firmly established as the gold standard diagnostic approach in interstitial lung diseases including HP. Nonetheless, the high interobserver variability between experts from the individual disciplines (pulmonology, radiology, and pathology) and between experienced multidisciplinary teams in assessing the diagnostic probability of HP has highlighted the need for widely accepted guidelines.The present review summarizes pathology-relevant aspects of the new ATS/JRS/ALAT clinical practice guideline for the diagnosis of HP in adults.
Document Type: Review
File Description: application/pdf
Language: German
Access URL: http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B26A4D252A713
https://serval.unil.ch/notice/serval:BIB_B26A4D252A71
https://serval.unil.ch/resource/serval:BIB_B26A4D252A71.P001/REF.pdf
Rights: CC BY
Accession Number: edsair.od......1900..d0978b45fa1d3cdbe1f22d0befb4155d
Database: OpenAIRE
Description
Abstract:Hypersensitivity pneumonia (HP), also called exogenous allergic alveolitis, is a chronic interstitial pneumonia induced by a hypersensitivity reaction to an identified or unidentified antigen in exposed and susceptible individuals that may progress to terminal lung fibrosis. The diagnosis of HP presents a diagnostic challenge. Though therapeutically important, it may be particularly difficult to differentiate fibrotic HP, historically termed chronic HP, from idiopathic pulmonary fibrosis (IPF) or interstitial lung disease associated with connective tissue diseases (CTD-ILD). Multidisciplinary discussion and thus a synoptic evaluation of all findings is firmly established as the gold standard diagnostic approach in interstitial lung diseases including HP. Nonetheless, the high interobserver variability between experts from the individual disciplines (pulmonology, radiology, and pathology) and between experienced multidisciplinary teams in assessing the diagnostic probability of HP has highlighted the need for widely accepted guidelines.The present review summarizes pathology-relevant aspects of the new ATS/JRS/ALAT clinical practice guideline for the diagnosis of HP in adults.