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Tumor lysis syndroom bij een hond

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Titel: Tumor lysis syndroom bij een hond
Autoren: Piek, C J, Teske, E
Quelle: Tijdschrift voor Diergeneeskunde. 121(3):64-66
Verlagsinformationen: Koninklijke Nederlandse Maatschappij voor Diergeneeskunde, 1996.
Publikationsjahr: 1996
Schlagwörter: Male, Dogs, Dog Diseases/chemically induced, Animals, Asparaginase/adverse effects, Antineoplastic Agents/adverse effects, Lymphoma/drug therapy, Tumor Lysis Syndrome/etiology
Beschreibung: The acute tumour lysis syndrome in humans as well as in dogs is caused by the acute lysis of tumour cells following chemotherapy. The release of intracellular products and their metabolites result in hyperkalemia, hyperphosphatemia, and hyperuricemia. The precipitation of uric acid and calciumphosphate in the kidneys can lead to hypocalcemia and acute renal failure which leads to fatal azotemia and arrhythmia's due to electrolyte disturbances. In this article the occurrence of the acute tumour lysis syndrome in a dog with malignant lymphoma is described. Suggestions to prevent the tumour lysis syndrome are made.
Publikationsart: Article
Sprache: Dutch; Flemish
ISSN: 0040-7453
Zugangs-URL: https://research-portal.uu.nl/en/publications/a156f5e5-3857-4812-9fc2-dab29cce15b2
Dokumentencode: edsair.dris...02462..1e0e7708eee57fcd7f3ecbe5ac0a648d
Datenbank: OpenAIRE
Beschreibung
Abstract:The acute tumour lysis syndrome in humans as well as in dogs is caused by the acute lysis of tumour cells following chemotherapy. The release of intracellular products and their metabolites result in hyperkalemia, hyperphosphatemia, and hyperuricemia. The precipitation of uric acid and calciumphosphate in the kidneys can lead to hypocalcemia and acute renal failure which leads to fatal azotemia and arrhythmia's due to electrolyte disturbances. In this article the occurrence of the acute tumour lysis syndrome in a dog with malignant lymphoma is described. Suggestions to prevent the tumour lysis syndrome are made.
ISSN:00407453