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Tumor lysis syndroom bij een hond

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Bibliographic Details
Title: Tumor lysis syndroom bij een hond
Authors: Piek, C J, Teske, E
Source: Tijdschrift voor Diergeneeskunde. 121(3):64-66
Publisher Information: Koninklijke Nederlandse Maatschappij voor Diergeneeskunde, 1996.
Publication Year: 1996
Subject Terms: Male, Dogs, Dog Diseases/chemically induced, Animals, Asparaginase/adverse effects, Antineoplastic Agents/adverse effects, Lymphoma/drug therapy, Tumor Lysis Syndrome/etiology
Description: The acute tumour lysis syndrome in humans as well as in dogs is caused by the acute lysis of tumour cells following chemotherapy. The release of intracellular products and their metabolites result in hyperkalemia, hyperphosphatemia, and hyperuricemia. The precipitation of uric acid and calciumphosphate in the kidneys can lead to hypocalcemia and acute renal failure which leads to fatal azotemia and arrhythmia's due to electrolyte disturbances. In this article the occurrence of the acute tumour lysis syndrome in a dog with malignant lymphoma is described. Suggestions to prevent the tumour lysis syndrome are made.
Document Type: Article
Language: Dutch; Flemish
ISSN: 0040-7453
Access URL: https://research-portal.uu.nl/en/publications/a156f5e5-3857-4812-9fc2-dab29cce15b2
Accession Number: edsair.dris...02462..1e0e7708eee57fcd7f3ecbe5ac0a648d
Database: OpenAIRE
Description
Abstract:The acute tumour lysis syndrome in humans as well as in dogs is caused by the acute lysis of tumour cells following chemotherapy. The release of intracellular products and their metabolites result in hyperkalemia, hyperphosphatemia, and hyperuricemia. The precipitation of uric acid and calciumphosphate in the kidneys can lead to hypocalcemia and acute renal failure which leads to fatal azotemia and arrhythmia's due to electrolyte disturbances. In this article the occurrence of the acute tumour lysis syndrome in a dog with malignant lymphoma is described. Suggestions to prevent the tumour lysis syndrome are made.
ISSN:00407453