Adverse Outcome of a Solitary Fibrous Tumor Originating in the Bladder

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Titel: Adverse Outcome of a Solitary Fibrous Tumor Originating in the Bladder
Autoren: Takato Nishino, Masaki Shimbo, Eri Fukagawa, Kazutaka Narimoto, Jun Hashimoto, Shin Ogita, Naoki Kanomata, Kazunori Hattori, Fumiyasu Endo
Quelle: IJU Case Rep
IJU Case Reports, Vol 8, Iss 3, Pp 231-235 (2025)
Verlagsinformationen: Wiley, 2025.
Publikationsjahr: 2025
Schlagwörter: robot‐assisted surgery, solitary fibrous tumor, Case Report, RC870-923, poor prognosis, metastases, urinary bladder, Diseases of the genitourinary system. Urology
Beschreibung: IntroductionSolitary fibrous tumors originating in the bladder are extremely rare. While generally associated with favorable outcomes, some show invasive behavior. We report a case of a solitary fibrous tumor originating in the bladder that was treated with multimodal therapy.Case PresentationA 68‐year‐old male presented with urinary retention. Imaging revealed a well‐defined 6.0 cm mass compressing the prostate. A biopsy suggested stromal sarcoma. Robot‐assisted cystoprostatectomy was performed. Pathological examination revealed a solitary fibrous tumor originating from the bladder invading the prostate. Despite negative margins, lung nodules and a pelvic mass appeared 43 months postoperatively. Initially, these were treated with pazopanib, followed by doxorubicin and eribulin due to disease progression. The patient eventually transitioned to palliative care and passed away 69 months after diagnosis.ConclusionThere are no effective systemic treatments for solitary fibrous tumors, which can lead to poor outcomes. Individualized treatment approaches are necessary.
Publikationsart: Article
Other literature type
Sprache: English
ISSN: 2577-171X
DOI: 10.1002/iju5.70013
Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40336741
https://doaj.org/article/8c0243576fcd4c5297c332ee317f3308
Rights: CC BY
Dokumentencode: edsair.doi.dedup.....f1ebc3d6dceba87d84ec7062325e8c04
Datenbank: OpenAIRE
Beschreibung
Abstract:IntroductionSolitary fibrous tumors originating in the bladder are extremely rare. While generally associated with favorable outcomes, some show invasive behavior. We report a case of a solitary fibrous tumor originating in the bladder that was treated with multimodal therapy.Case PresentationA 68‐year‐old male presented with urinary retention. Imaging revealed a well‐defined 6.0 cm mass compressing the prostate. A biopsy suggested stromal sarcoma. Robot‐assisted cystoprostatectomy was performed. Pathological examination revealed a solitary fibrous tumor originating from the bladder invading the prostate. Despite negative margins, lung nodules and a pelvic mass appeared 43 months postoperatively. Initially, these were treated with pazopanib, followed by doxorubicin and eribulin due to disease progression. The patient eventually transitioned to palliative care and passed away 69 months after diagnosis.ConclusionThere are no effective systemic treatments for solitary fibrous tumors, which can lead to poor outcomes. Individualized treatment approaches are necessary.
ISSN:2577171X
DOI:10.1002/iju5.70013