Diffusion-tensor magnetic resonance imaging in children with language impairment
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| Title: | Diffusion-tensor magnetic resonance imaging in children with language impairment |
|---|---|
| Authors: | Dong-Ik Kim, Jinna Kim, Seung Koo Lee, Eun Sook Park, Chang-Il Park, Yong Wook Kim, HyangHee Kim |
| Contributors: | Jinna Kim, Yong Wook Kim, Chang-il Park, Eun Sook Park, Hyang-Hee Kim, Seung-Koo Lee, Dong Ik Kim, Kim, Dong Ik, Kim, Yong Wook, Kim, Jinna, Kim, Hyang Hee, Park, Chang Il, Lee, Seung Koo |
| Source: | NeuroReport. 17:1279-1282 |
| Publisher Information: | Ovid Technologies (Wolters Kluwer Health), 2006. |
| Publication Year: | 2006 |
| Subject Terms: | Male, Brain Mapping, Language Disorders, di¡usion tensor imaging, Diffusion Magnetic Resonance Imaging, Image Processing, language impairment, Computer-Assisted/methods, 03 medical and health sciences, 0302 clinical medicine, children, Child, Preschool, Image Processing, Computer-Assisted, Anisotropy, Humans, Female, Language Disorders/diagnosis, Preschool, Child |
| Description: | We evaluated the integrity of the white matter tract using diffusion-tensor magnetic resonance imaging in children with language impairments who exhibited a structurally normal brain on conventional magnetic resonance imaging, and compared it with age-matched normal children. After generating fractional anisotropy and color-coded vector maps, fractional anisotropy values of the major white matter tracts were measured in six locations and compared between the two groups. Compared with the normal control group, the fractional anisotropy values of children with language impairments showed a statistically significant reduction in the genu of the corpus callosum, which is rarely revealed on conventional magnetic resonance images. Our results suggest that delayed maturation of the white matter plays a partial role in the pathophysiological mechanisms of language impairments. |
| Document Type: | Article |
| File Description: | 1279~1282 |
| Language: | English |
| ISSN: | 0959-4965 |
| DOI: | 10.1097/01.wnr.0000230516.86090.67 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/16951569 http://www.brainresearch.us/DTI_MRI_in_children_with_language_impairment.pdf https://www.ncbi.nlm.nih.gov/pubmed/16951569 http://journals.lww.com/00006534-200606000-00010 https://ir.ymlib.yonsei.ac.kr/handle/22282913/110766 https://pubmed.ncbi.nlm.nih.gov/16951569/ |
| Rights: | CC BY NC ND |
| Accession Number: | edsair.doi.dedup.....c7b39854c607a099c3dea4328c65e11c |
| Database: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstract: | We evaluated the integrity of the white matter tract using diffusion-tensor magnetic resonance imaging in children with language impairments who exhibited a structurally normal brain on conventional magnetic resonance imaging, and compared it with age-matched normal children. After generating fractional anisotropy and color-coded vector maps, fractional anisotropy values of the major white matter tracts were measured in six locations and compared between the two groups. Compared with the normal control group, the fractional anisotropy values of children with language impairments showed a statistically significant reduction in the genu of the corpus callosum, which is rarely revealed on conventional magnetic resonance images. Our results suggest that delayed maturation of the white matter plays a partial role in the pathophysiological mechanisms of language impairments. |
|---|---|
| ISSN: | 09594965 |
| DOI: | 10.1097/01.wnr.0000230516.86090.67 |