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Fatigue is associated with depression independent of excessive daytime sleepiness in the general population

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Název: Fatigue is associated with depression independent of excessive daytime sleepiness in the general population
Autoři: Min Kyung Chu, Jun Sang Sunwoo, Daeyoung Kim, Kwang Ik Yang, Chang-Ho Yun
Přispěvatelé: Jun-Sang Sunwoo, Daeyoung Kim, Min Kyung Chu, Chang-Ho Yun, Kwang Ik Yang, Chu, Min Kyung
Zdroj: Sleep and Breathing. 26:933-940
Informace o vydavateli: Springer Science and Business Media LLC, 2021.
Rok vydání: 2021
Témata: Adult, Male, Sleep Wake Disorders, Sleepiness, Disorders of Excessive Somnolence, Disorders of Excessive Somnolence* / diagnosis, 03 medical and health sciences, 0302 clinical medicine, Disorders of Excessive Somnolence* / epidemiology, Depression / complications, Depression / epidemiology, Humans, Depression / diagnosis, Fatigue, Sleep Wake Disorders* / complications, Sleep duration, Depression, Middle Aged, Fatigue / epidemiology, 3. Good health, Cross-Sectional Studies, Female, Disorders of Excessive Somnolence* / complications, Sleep, Fatigue / complications
Popis: This study aimed to investigate sleep problems and comorbid conditions associated with fatigue in the general population.The data were obtained from a nationwide cross-sectional survey conducted in 2018. The Fatigue Severity Scale was used to assess fatigue. We examined sleep habits, such as workday sleep duration, chronotype, and free-day catch-up sleep, excessive daytime sleepiness (EDS), depression, and other comorbid conditions. We conducted multiple logistic regression analysis with the presence of fatigue as a dependent variable.Of 2,493 adults aged 19 to 92 years, 50% men, mean age was 47.9 ± 16.4 years. The average workday sleep duration was 7.1 ± 1.1 h, and the prevalence of fatigue was 31%. After adjusting for potential confounders, fatigue was associated with EDS (odds ratio [OR] 3.751, 95% confidence interval [CI] 2.928-4.805), depression (OR 3.736, 95% CI 2.701-5.169), perceived insufficient sleep (OR 1.516, 95% CI 1.249-1.839), free-day catch-up sleep (OR 1.123, 95% CI 1.020-1.235), less alcohol intake (OR 0.570, 95% CI 0.432-0.752), and physical inactivity (OR 0.737, 95% CI 0.573-0.948). On subgroup analysis, fatigue was additionally associated with short workday sleep duration (OR 0.899, 95% CI 0.810-0.997) in individuals without EDS. However, among those with EDS, only depression (OR 2.842, 95% CI 1.511-5.343) and less alcohol intake (OR 0.476, 95% CI 0.247-0.915) were associated with fatigue.Fatigue was significantly associated with depression independent of EDS. Further research is warranted to better understand the pathophysiological relationship between fatigue, depression, and sleep.
Druh dokumentu: Article
Jazyk: English
ISSN: 1522-1709
1520-9512
DOI: 10.1007/s11325-021-02448-3
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/34292460
https://pubmed.ncbi.nlm.nih.gov/34292460/
https://snucm.elsevierpure.com/en/publications/fatigue-is-associated-with-depression-independent-of-excessive-da
https://link.springer.com/article/10.1007/s11325-021-02448-3
Rights: Springer TDM
CC BY NC ND
Přístupové číslo: edsair.doi.dedup.....b6d023a31e81e11e44ca194436565f3f
Databáze: OpenAIRE
Popis
Abstrakt:This study aimed to investigate sleep problems and comorbid conditions associated with fatigue in the general population.The data were obtained from a nationwide cross-sectional survey conducted in 2018. The Fatigue Severity Scale was used to assess fatigue. We examined sleep habits, such as workday sleep duration, chronotype, and free-day catch-up sleep, excessive daytime sleepiness (EDS), depression, and other comorbid conditions. We conducted multiple logistic regression analysis with the presence of fatigue as a dependent variable.Of 2,493 adults aged 19 to 92 years, 50% men, mean age was 47.9 ± 16.4 years. The average workday sleep duration was 7.1 ± 1.1 h, and the prevalence of fatigue was 31%. After adjusting for potential confounders, fatigue was associated with EDS (odds ratio [OR] 3.751, 95% confidence interval [CI] 2.928-4.805), depression (OR 3.736, 95% CI 2.701-5.169), perceived insufficient sleep (OR 1.516, 95% CI 1.249-1.839), free-day catch-up sleep (OR 1.123, 95% CI 1.020-1.235), less alcohol intake (OR 0.570, 95% CI 0.432-0.752), and physical inactivity (OR 0.737, 95% CI 0.573-0.948). On subgroup analysis, fatigue was additionally associated with short workday sleep duration (OR 0.899, 95% CI 0.810-0.997) in individuals without EDS. However, among those with EDS, only depression (OR 2.842, 95% CI 1.511-5.343) and less alcohol intake (OR 0.476, 95% CI 0.247-0.915) were associated with fatigue.Fatigue was significantly associated with depression independent of EDS. Further research is warranted to better understand the pathophysiological relationship between fatigue, depression, and sleep.
ISSN:15221709
15209512
DOI:10.1007/s11325-021-02448-3