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Sex-related functional outcome after periacetabular osteotomy in mild to severe hip dysplasia

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Titel: Sex-related functional outcome after periacetabular osteotomy in mild to severe hip dysplasia
Autoren: Maximilian Fischer, Lars Nonnenmacher, Andre Hofer, Alexander Zimmerer, Andreas Nitsch, Rico Großjohann, Sabrina Erdmann, Georgi I. Wassilew
Quelle: Bone Jt Open
Bone & Joint Open, Vol 6, Iss 1, Pp 35-42 (2025)
Verlagsinformationen: British Editorial Society of Bone & Joint Surgery, 2025.
Publikationsjahr: 2025
Schlagwörter: hip disability and osteoarthritis outcome score, Orthopedic surgery, sex-related outcome, patient-reported outcome measures (proms), Hip, proms, periacetabular osteotomy, hip dysplasia, acetabular dysplasia, university of california, los angeles (ucla) activity score, clinical outcomes, functional outcome, hips, pao, bmi, modified harris hip score, hip preservation, RD701-811
Beschreibung: AimsPeriacetabular osteotomy (PAO) is well established for acetabular reorientation and has shown successful improvement in patient-reported outcome measures (PROMs). Nevertheless, studies focusing on postoperative outcomes related to patient individual factors are still underrepresented. Therefore, this study aimed to analyze the functional outcome and activity level in relation to patient sex with a minimum follow-up of two years after PAO for mild to severe hip dysplasia.MethodsA single-centre study was conducted, enrolling patients undergoing PAO and completing a preoperative and postoperative radiological and clinical outcome assessment. The PROMs were assessed using the modified Harris Hip Score (mHHS), the Hip disability and Osteoarthritis Outcome Score (HOOS) with the subscales for pain, sport, activities of daily living (ADL), and quality of life (QoL), and the University of California, Los Angeles (UCLA) activity score. Kendall’s tau were calculated for correlation analyses.ResultsIn total, 145 patients (28 male, 117 female) were included. The PROMs improved significantly across males and females at the latest follow-up. Female patients had significantly lower preoperative PROMs: mHHS (47 vs 57.4; p = 0.002); HOOS pain (44.9 vs 60; p = 0.003), sport (47 vs 57.4; p = 0.002), ADL (58.9 vs 69.3; p = 0.032), and QoL (26.8 vs 39.3; p = 0.009); and UCLA (5.6 vs 6.7, p = 0.042) scores. Males showed higher postoperative UCLA scores (7.5 vs 6.7; p = 0.03). Kendall’s tau showed significant negative correlation between BMI and UCLA scores in females and males (-0.21 to -0.29; p = 0.002/0.048), while BMI and HOOS sport (-0.16; p = 0.015) and ADL (-0.2; p = 0.003), as well as QoL (-0.14; p = 0.031) and preoperative acetabular inclination (-0.13; p = 0.049) were only significantly negatively correlated in females.ConclusionPatient sex affects PROMs before and after PAO. Female patients experience higher improvement in hip function and activity level, due to poorer preoperative PROMs than males. Thus, these data are particularly interesting in providing preoperative guidance regarding postoperative outcome expectations.Cite this article: Bone Jt Open 2024;6(1):35–42.
Publikationsart: Article
Other literature type
Sprache: English
ISSN: 2633-1462
DOI: 10.1302/2633-1462.61.bjo-2024-0038.r1
Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39773535
https://doaj.org/article/9bd22eba6aa6433fba553c3b27802aec
Rights: CC BY NC ND
URL: http://creativecommons.org/licenses/by-nc-nd/4.0/http://online.boneandjoint.org.uk/TDMThis is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See http://creativecommons.org/licenses/by-nc-nd/4.0/
Dokumentencode: edsair.doi.dedup.....878eda62f4782b49b67bcf0e3f8ca5c4
Datenbank: OpenAIRE
Beschreibung
Abstract:AimsPeriacetabular osteotomy (PAO) is well established for acetabular reorientation and has shown successful improvement in patient-reported outcome measures (PROMs). Nevertheless, studies focusing on postoperative outcomes related to patient individual factors are still underrepresented. Therefore, this study aimed to analyze the functional outcome and activity level in relation to patient sex with a minimum follow-up of two years after PAO for mild to severe hip dysplasia.MethodsA single-centre study was conducted, enrolling patients undergoing PAO and completing a preoperative and postoperative radiological and clinical outcome assessment. The PROMs were assessed using the modified Harris Hip Score (mHHS), the Hip disability and Osteoarthritis Outcome Score (HOOS) with the subscales for pain, sport, activities of daily living (ADL), and quality of life (QoL), and the University of California, Los Angeles (UCLA) activity score. Kendall’s tau were calculated for correlation analyses.ResultsIn total, 145 patients (28 male, 117 female) were included. The PROMs improved significantly across males and females at the latest follow-up. Female patients had significantly lower preoperative PROMs: mHHS (47 vs 57.4; p = 0.002); HOOS pain (44.9 vs 60; p = 0.003), sport (47 vs 57.4; p = 0.002), ADL (58.9 vs 69.3; p = 0.032), and QoL (26.8 vs 39.3; p = 0.009); and UCLA (5.6 vs 6.7, p = 0.042) scores. Males showed higher postoperative UCLA scores (7.5 vs 6.7; p = 0.03). Kendall’s tau showed significant negative correlation between BMI and UCLA scores in females and males (-0.21 to -0.29; p = 0.002/0.048), while BMI and HOOS sport (-0.16; p = 0.015) and ADL (-0.2; p = 0.003), as well as QoL (-0.14; p = 0.031) and preoperative acetabular inclination (-0.13; p = 0.049) were only significantly negatively correlated in females.ConclusionPatient sex affects PROMs before and after PAO. Female patients experience higher improvement in hip function and activity level, due to poorer preoperative PROMs than males. Thus, these data are particularly interesting in providing preoperative guidance regarding postoperative outcome expectations.Cite this article: Bone Jt Open 2024;6(1):35–42.
ISSN:26331462
DOI:10.1302/2633-1462.61.bjo-2024-0038.r1