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MAMBO-NET: Multi-causal aware modeling backdoor-intervention optimization for medical image segmentation network

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Title: MAMBO-NET: Multi-causal aware modeling backdoor-intervention optimization for medical image segmentation network
Authors: Yu, Ruiguo, Zhang, Yiyang, Tian, Yuan, Diao, Yujie, Jin, Di, Pedrycz, Witold
Source: Pattern Recognition Letters. 197:102-109
Publication Status: Preprint
Publisher Information: Elsevier BV, 2025.
Publication Year: 2025
Subject Terms: FOS: Computer and information sciences, Computer Vision and Pattern Recognition (cs.CV), Image and Video Processing (eess.IV), Computer Science - Computer Vision and Pattern Recognition, FOS: Electrical engineering, electronic engineering, information engineering, Electrical Engineering and Systems Science - Image and Video Processing
Description: Medical image segmentation methods generally assume that the process from medical image to segmentation is unbiased, and use neural networks to establish conditional probability models to complete the segmentation task. This assumption does not consider confusion factors, which can affect medical images, such as complex anatomical variations and imaging modality limitations. Confusion factors obfuscate the relevance and causality of medical image segmentation, leading to unsatisfactory segmentation results. To address this issue, we propose a multi-causal aware modeling backdoor-intervention optimization (MAMBO-NET) network for medical image segmentation. Drawing insights from causal inference, MAMBO-NET utilizes self-modeling with multi-Gaussian distributions to fit the confusion factors and introduce causal intervention into the segmentation process. Moreover, we design appropriate posterior probability constraints to effectively train the distributions of confusion factors. For the distributions to effectively guide the segmentation and mitigate and eliminate the Impact of confusion factors on the segmentation, we introduce classical backdoor intervention techniques and analyze their feasibility in the segmentation task. To evaluate the effectiveness of our approach, we conducted extensive experiments on five medical image datasets. The results demonstrate that our method significantly reduces the influence of confusion factors, leading to enhanced segmentation accuracy.
Document Type: Article
Language: English
ISSN: 0167-8655
DOI: 10.1016/j.patrec.2025.06.016
DOI: 10.48550/arxiv.2505.21874
Access URL: http://arxiv.org/abs/2505.21874
Rights: Elsevier TDM
CC BY
Accession Number: edsair.doi.dedup.....797dc2f671ff98e6bd2480a8bfd13d6f
Database: OpenAIRE
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  Data: MAMBO-NET: Multi-causal aware modeling backdoor-intervention optimization for medical image segmentation network
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  Data: <searchLink fieldCode="AR" term="%22Yu%2C+Ruiguo%22">Yu, Ruiguo</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Yiyang%22">Zhang, Yiyang</searchLink><br /><searchLink fieldCode="AR" term="%22Tian%2C+Yuan%22">Tian, Yuan</searchLink><br /><searchLink fieldCode="AR" term="%22Diao%2C+Yujie%22">Diao, Yujie</searchLink><br /><searchLink fieldCode="AR" term="%22Jin%2C+Di%22">Jin, Di</searchLink><br /><searchLink fieldCode="AR" term="%22Pedrycz%2C+Witold%22">Pedrycz, Witold</searchLink>
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  Data: Medical image segmentation methods generally assume that the process from medical image to segmentation is unbiased, and use neural networks to establish conditional probability models to complete the segmentation task. This assumption does not consider confusion factors, which can affect medical images, such as complex anatomical variations and imaging modality limitations. Confusion factors obfuscate the relevance and causality of medical image segmentation, leading to unsatisfactory segmentation results. To address this issue, we propose a multi-causal aware modeling backdoor-intervention optimization (MAMBO-NET) network for medical image segmentation. Drawing insights from causal inference, MAMBO-NET utilizes self-modeling with multi-Gaussian distributions to fit the confusion factors and introduce causal intervention into the segmentation process. Moreover, we design appropriate posterior probability constraints to effectively train the distributions of confusion factors. For the distributions to effectively guide the segmentation and mitigate and eliminate the Impact of confusion factors on the segmentation, we introduce classical backdoor intervention techniques and analyze their feasibility in the segmentation task. To evaluate the effectiveness of our approach, we conducted extensive experiments on five medical image datasets. The results demonstrate that our method significantly reduces the influence of confusion factors, leading to enhanced segmentation accuracy.
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      – SubjectFull: Computer Vision and Pattern Recognition (cs.CV)
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      – SubjectFull: FOS: Electrical engineering, electronic engineering, information engineering
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      – SubjectFull: Electrical Engineering and Systems Science - Image and Video Processing
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      – TitleFull: MAMBO-NET: Multi-causal aware modeling backdoor-intervention optimization for medical image segmentation network
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            NameFull: Yu, Ruiguo
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