'Get with the Guidelines Heart Failure Risk Score' for mortality prediction in patients undergoing MitraClip
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| Název: | 'Get with the Guidelines Heart Failure Risk Score' for mortality prediction in patients undergoing MitraClip |
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| Autoři: | Christos Iliadis, Maximilian Spieker, Refik Kavsur, Clemens Metze, Martin Hellmich, Patrick Horn, Ralf Westenfeld, Vedat Tiyerili, Marc Ulrich Becher, Malte Kelm, Georg Nickenig, Stephan Baldus, Roman Pfister |
| Zdroj: | Clin Res Cardiol |
| Informace o vydavateli: | Springer Science and Business Media LLC, 2021. |
| Rok vydání: | 2021 |
| Témata: | Aged, 80 and over, Male, 2. Zero hunger, Original Paper, Cardiac Catheterization, Mitral Valve Insufficiency, Stroke Volume, Ventricular Function, Left, 3. Good health, Survival Rate, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Germany, Humans, Female, Guideline Adherence, Cardiac Surgical Procedures, Female [MeSH], Aged, 80 and over [MeSH], Heart failure, Survival Rate/trends [MeSH], Aged [MeSH], Mitral Valve Insufficiency/surgery [MeSH], Humans [MeSH], Mitral Valve Insufficiency/physiopathology [MeSH], Cardiac Catheterization/methods [MeSH], Retrospective Studies [MeSH], Risk Factors [MeSH], MitraClip, Stroke Volume/physiology [MeSH], Germany/epidemiology [MeSH], Ventricular Function, Left/physiology [MeSH], Cardiac Surgical Procedures/methods [MeSH], Mortality, Male [MeSH], Get with the guidelines heart failure risk score, Guideline Adherence [MeSH], Mitral Valve Insufficiency/mortality [MeSH], Aged, Retrospective Studies |
| Popis: | Background Reliable risk scores in patients undergoing transcatheter edge-to-edge mitral valve repair (TMVR) are lacking. Heart failure is common in these patients, and risk scores derived from heart failure populations might help stratify TMVR patients. Methods Consecutive patients from three Heart Centers undergoing TMVR were enrolled to investigate the association of the “Get with the Guidelines Heart Failure Risk Score” (comprising the variables systolic blood pressure, urea nitrogen, blood sodium, age, heart rate, race, history of chronic obstructive lung disease) with all-cause mortality. Results Among 815 patients with available data 177 patients died during a median follow-up time of 365 days. Estimated 1-year mortality by quartiles of the score (0–37; 38–42, 43–46 and more than 46 points) was 6%, 10%, 23% and 30%, respectively (p p = 0.46). Every increase of one score point was associated with a 9% increase in the hazard of mortality (95% CI 1.06–1.11%, p Conclusion The “Get with the Guidelines Heart Failure Risk Score” showed a strong association with mortality in patients undergoing TMVR with additive information beyond traditional risk factors. Given the routinely available variables included in this score, application is easy and broadly possible. Graphic abstract |
| Druh dokumentu: | Article Other literature type |
| Jazyk: | English |
| ISSN: | 1861-0692 1861-0684 |
| DOI: | 10.1007/s00392-021-01804-3 |
| Přístupová URL adresa: | https://link.springer.com/content/pdf/10.1007/s00392-021-01804-3.pdf https://pubmed.ncbi.nlm.nih.gov/33517496 https://link.springer.com/article/10.1007/s00392-021-01804-3 https://www.ncbi.nlm.nih.gov/pubmed/33517496 https://europepmc.org/article/MED/33517496 https://link.springer.com/content/pdf/10.1007/s00392-021-01804-3.pdf https://pubmed.ncbi.nlm.nih.gov/33517496/ https://www.scilit.net/article/a5694484a90a557d6b5d3f4e35085bc6 https://repository.publisso.de/resource/frl:6447575 |
| Rights: | CC BY URL: http://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (http://creativecommons.org/licenses/by/4.0/) . |
| Přístupové číslo: | edsair.doi.dedup.....6cb76f86af931275c5eeefa2f1316f3d |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Background Reliable risk scores in patients undergoing transcatheter edge-to-edge mitral valve repair (TMVR) are lacking. Heart failure is common in these patients, and risk scores derived from heart failure populations might help stratify TMVR patients. Methods Consecutive patients from three Heart Centers undergoing TMVR were enrolled to investigate the association of the “Get with the Guidelines Heart Failure Risk Score” (comprising the variables systolic blood pressure, urea nitrogen, blood sodium, age, heart rate, race, history of chronic obstructive lung disease) with all-cause mortality. Results Among 815 patients with available data 177 patients died during a median follow-up time of 365 days. Estimated 1-year mortality by quartiles of the score (0–37; 38–42, 43–46 and more than 46 points) was 6%, 10%, 23% and 30%, respectively (p p = 0.46). Every increase of one score point was associated with a 9% increase in the hazard of mortality (95% CI 1.06–1.11%, p Conclusion The “Get with the Guidelines Heart Failure Risk Score” showed a strong association with mortality in patients undergoing TMVR with additive information beyond traditional risk factors. Given the routinely available variables included in this score, application is easy and broadly possible. Graphic abstract |
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| ISSN: | 18610692 18610684 |
| DOI: | 10.1007/s00392-021-01804-3 |