A Practical Fixed-Parameter Algorithm for Constructing Tree-Child Networks from Multiple Binary Trees

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Bibliographic Details
Title: A Practical Fixed-Parameter Algorithm for Constructing Tree-Child Networks from Multiple Binary Trees
Authors: Leo van Iersel, Remie Janssen, Mark Jones, Yukihiro Murakami, Norbert Zeh
Source: Algorithmica. 84:917-960
Publication Status: Preprint
Publisher Information: Springer Science and Business Media LLC, 2022.
Publication Year: 2022
Subject Terms: FOS: Computer and information sciences, Discrete Mathematics (cs.DM), 0206 medical engineering, Populations and Evolution (q-bio.PE), 0102 computer and information sciences, 02 engineering and technology, Fixed-parameter algorithms, 01 natural sciences, Phylogenetic networks, FOS: Biological sciences, FOS: Mathematics, Mathematics - Combinatorics, Combinatorics (math.CO), Hybridization number, Quantitative Biology - Populations and Evolution, 92D15 05C90 05C85 56R10, Computer Science - Discrete Mathematics
Description: We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm uses the recently introduced framework of cherry picking sequences and runs in $O((8k)^k \mathrm{poly}(n, t))$ time, where $n$ is the number of leaves of every tree, $t$ is the number of trees, and $k$ is the reticulation number of the constructed network. Moreover, we provide an efficient parallel implementation of the algorithm and show that it can deal with up to $100$ input trees on a standard desktop computer, thereby providing a major improvement over previous phylogenetic network construction methods.
Code available at https://github.com/nzeh/tree_child_code
Document Type: Article
Language: English
ISSN: 1432-0541
0178-4617
DOI: 10.1007/s00453-021-00914-8
DOI: 10.48550/arxiv.1907.08474
Access URL: http://arxiv.org/pdf/1907.08474
http://arxiv.org/abs/1907.08474
http://resolver.tudelft.nl/uuid:70e72477-d616-4b6f-a275-f16df603453b
Rights: Springer TDM
arXiv Non-Exclusive Distribution
Accession Number: edsair.doi.dedup.....5b67a80e5be6fd1c4d01c9c0a5a2c2c6
Database: OpenAIRE
Description
Abstract:We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm uses the recently introduced framework of cherry picking sequences and runs in $O((8k)^k \mathrm{poly}(n, t))$ time, where $n$ is the number of leaves of every tree, $t$ is the number of trees, and $k$ is the reticulation number of the constructed network. Moreover, we provide an efficient parallel implementation of the algorithm and show that it can deal with up to $100$ input trees on a standard desktop computer, thereby providing a major improvement over previous phylogenetic network construction methods.<br />Code available at https://github.com/nzeh/tree_child_code
ISSN:14320541
01784617
DOI:10.1007/s00453-021-00914-8