Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden
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| Title: | Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden |
|---|---|
| Authors: | Hashim D., Genden E., Posner M., Hashibe M., Boffetta P. |
| Source: | Annals of Oncology. 30:744-756 |
| Publisher Information: | Elsevier BV, 2019. |
| Publication Year: | 2019 |
| Subject Terms: | Primary Prevention, 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, Head and Neck Neoplasms, cancer prevention, dentists, early detection of cancer/statistics & numerical data, head and neck neoplasms, mouth neoplasms, mouth neoplasms/diagnosis, Humans, Healthy Lifestyle, Pathology, Molecular, Practice Patterns, Physicians', 3. Good health |
| Description: | Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such as tobacco smoking, alcohol drinking, and betel quid chewing are highly prevalent but tertiary health care center access is limited or unavailable. Early diagnosis of HNC is the most important prognostic factor for each tumor site. Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression. Future investments for HNC control must consider both effectiveness and sustainability for both high- and low-resource countries alike, with priority toward risk factor prevention and earlier diagnosis. |
| Document Type: | Article |
| Language: | English |
| ISSN: | 0923-7534 |
| DOI: | 10.1093/annonc/mdz084 |
| Access URL: | http://www.annalsofoncology.org/article/S0923753419311706/pdf https://pubmed.ncbi.nlm.nih.gov/30840052 https://europepmc.org/article/MED/30840052 https://www.annalsofoncology.org/article/S0923-7534(19)31170-6/fulltext https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551449 https://academic.oup.com/annonc/article/30/5/744/5370174 https://www.sciencedirect.com/science/article/pii/S0923753419311706 https://www.annalsofoncology.org/article/S0923753419311706/pdf https://hdl.handle.net/11585/737443 https://doi.org/10.1093/annonc/mdz084 |
| Rights: | Elsevier Non-Commercial |
| Accession Number: | edsair.doi.dedup.....3a19a4edecfc862bf179e2ff528c8aff |
| Database: | OpenAIRE |
| Abstract: | Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has increased by 10% over the past few decades. Little over half of patients who develop HNCs will survive beyond 5 years. Survival is lower for individuals in many countries where traditional risk factors such as tobacco smoking, alcohol drinking, and betel quid chewing are highly prevalent but tertiary health care center access is limited or unavailable. Early diagnosis of HNC is the most important prognostic factor for each tumor site. Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression. Future investments for HNC control must consider both effectiveness and sustainability for both high- and low-resource countries alike, with priority toward risk factor prevention and earlier diagnosis. |
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| ISSN: | 09237534 |
| DOI: | 10.1093/annonc/mdz084 |
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