Toksisk forbrug af baclofen med kramper ved udtrapning

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Bibliographic Details
Title: Toksisk forbrug af baclofen med kramper ved udtrapning
Authors: Isidor, Søren, Laursen, Tea L., Bundgaard, Helle, Sædder, Eva A., Helgestad, Ole Kl
Source: Isidor, S, Laursen, T L, Bundgaard, H, Sædder, E A & Helgestad, O K 2023, 'Toksisk forbrug af baclofen med kramper ved udtrapning', Ugeskrift for Læger, bind 185, nr. 13, V09220530.
Publisher Information: 2023.
Publication Year: 2023
Subject Terms: Baclofen, Midazolam/therapeutic use, Humans, Female, Hypnotics and Sedatives/adverse effects, Propofol/adverse effects, Middle Aged, 3. Good health, Muscle Cramp
Description: The spasmolytic agent baclofen is regarded as having a low dependence potential. This is a case report of a 46-year-old woman with an escalating use of baclofen to four times the highest recommended dose. She was initially admitted to hospital due to decreased consciousness. Later, during tapering, she was readmitted unresponsive with myoclonus. Baclofen was discontinued abruptly during sedation with propofol and remifentanil infusion as well as midazolam in refract doses. Eight days later she was discharged without sequelae.
Document Type: Article
File Description: application/pdf
Language: Danish
Access URL: https://pure.au.dk/portal/en/publications/bf9f0bd2-8e5b-4a91-87ba-f663983a3eef
https://pure.au.dk/portal/en/publications/bf9f0bd2-8e5b-4a91-87ba-f663983a3eef
http://www.scopus.com/inward/record.url?scp=85151316069&partnerID=8YFLogxK
https://pure.au.dk/ws/files/417000689/Toksisk_forbrug_af_baclofen_med_kramper_ved_udtrapning.pdf
Rights: CC BY NC ND
Accession Number: edsair.dedup.wf.002..05fd60f02c432a5e1e378e4a101dd1a6
Database: OpenAIRE
Description
Abstract:The spasmolytic agent baclofen is regarded as having a low dependence potential. This is a case report of a 46-year-old woman with an escalating use of baclofen to four times the highest recommended dose. She was initially admitted to hospital due to decreased consciousness. Later, during tapering, she was readmitted unresponsive with myoclonus. Baclofen was discontinued abruptly during sedation with propofol and remifentanil infusion as well as midazolam in refract doses. Eight days later she was discharged without sequelae.