Toksisk forbrug af baclofen med kramper ved udtrapning
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| Title: | Toksisk forbrug af baclofen med kramper ved udtrapning |
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| Authors: | Isidor, Søren, Laursen, Tea L., Bundgaard, Helle, Sædder, Eva A., Helgestad, Ole Kl |
| Source: | Isidor, S, Laursen, T L, Bundgaard, H, Sædder, E A & Helgestad, O K 2023, 'Toksisk forbrug af baclofen med kramper ved udtrapning', Ugeskrift for Læger, bind 185, nr. 13, V09220530. |
| Publisher Information: | 2023. |
| Publication Year: | 2023 |
| Subject Terms: | Baclofen, Midazolam/therapeutic use, Humans, Female, Hypnotics and Sedatives/adverse effects, Propofol/adverse effects, Middle Aged, 3. Good health, Muscle Cramp |
| Description: | The spasmolytic agent baclofen is regarded as having a low dependence potential. This is a case report of a 46-year-old woman with an escalating use of baclofen to four times the highest recommended dose. She was initially admitted to hospital due to decreased consciousness. Later, during tapering, she was readmitted unresponsive with myoclonus. Baclofen was discontinued abruptly during sedation with propofol and remifentanil infusion as well as midazolam in refract doses. Eight days later she was discharged without sequelae. |
| Document Type: | Article |
| File Description: | application/pdf |
| Language: | Danish |
| Access URL: | https://pure.au.dk/portal/en/publications/bf9f0bd2-8e5b-4a91-87ba-f663983a3eef https://pure.au.dk/portal/en/publications/bf9f0bd2-8e5b-4a91-87ba-f663983a3eef http://www.scopus.com/inward/record.url?scp=85151316069&partnerID=8YFLogxK https://pure.au.dk/ws/files/417000689/Toksisk_forbrug_af_baclofen_med_kramper_ved_udtrapning.pdf |
| Rights: | CC BY NC ND |
| Accession Number: | edsair.dedup.wf.002..05fd60f02c432a5e1e378e4a101dd1a6 |
| Database: | OpenAIRE |
| Abstract: | The spasmolytic agent baclofen is regarded as having a low dependence potential. This is a case report of a 46-year-old woman with an escalating use of baclofen to four times the highest recommended dose. She was initially admitted to hospital due to decreased consciousness. Later, during tapering, she was readmitted unresponsive with myoclonus. Baclofen was discontinued abruptly during sedation with propofol and remifentanil infusion as well as midazolam in refract doses. Eight days later she was discharged without sequelae. |
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