The Design and Development of an Integrated Natural Products Screening Database.
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| Title: | The Design and Development of an Integrated Natural Products Screening Database. |
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| Authors: | Holt, Tom G., Dufresne, Claude, Liesch, Jerrold M., Mallow, Gary K. |
| Source: | Journal of Biomolecular Screening; Dec2000, Vol. 5 Issue 6, p421-433, 13p |
| Abstract: | We designed and developed NEXUS—a new natural products screening database and related suite of software applications-to utilize the spectacular increases in assay capacity of the modern high throughput screening (HTS) environment. NEXUS not only supports seamless integration with separate HTS systems, but supports user-customized integration with external laboratory automation, particularly sample preparation systems. Designed and developed based on a detailed process model for natural products drug discovery, NEXUS comprises two integrated parts: (1) a single schema of Oracle tables and callable procedures and functions, and (2) software "front-ends" to the database developed using Microsoft Excel and Oracle Discovery/2000. Many of the back-end processing functions were written in Programming Language/Structured Query Language (PL/SQL) to provide an Application Programmer's Interface, which allows end users to create custom applications with little input from information technology professionals. [ABSTRACT FROM PUBLISHER] |
| Copyright of Journal of Biomolecular Screening is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Biomedical Index |
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