Modeling factors affecting the design and manufacture of the recombinant vaccine: Key points for health policymakers and professionals.
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| Title: | Modeling factors affecting the design and manufacture of the recombinant vaccine: Key points for health policymakers and professionals. |
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| Authors: | Bahadori, Mohammadkarim, Mohammadian, Mohammad, Farajzadeh, Mohsen Abbasi, Ravangard, Ramin |
| Source: | International Journal of Healthcare Management; Nov2025, Vol. 18 Issue 4, p724-732, 9p |
| Subject Terms: | COVID-19, HEALTH policy, TECHNICAL specifications, TECHNOLOGICAL innovations, MANUFACTURING industries, DECISION making, CLINICAL trials, PEPTIDE vaccines |
| Geographic Terms: | IRAN |
| Abstract: | Objective: The study aimed to model factors affecting the design and manufacture of recombinant vaccines in Iran during the Covid-19 pandemic. Methods: The present study was a descriptive-analytical and cross-sectional study conducted in 2022. The study sample included 8 policymakers, decision-makers, and specialists involved in vaccine design and manufacturing. Both qualitative and quantitative methods were used to collect data. The Brainwriting technique was used to identify factors affecting vaccine design and manufacturing, and the Decision-Making Trial and Evaluation (DEMATEL) technique was used to analyze the systematic relationships between components. Results: The qualitative stage of the study identified seven themes affecting vaccine design and manufacture: disease nature, macro policies, official support, research networks, vaccine type selection, production process, and clinical trials. The nature of the disease (coordinates C: [2.78, 1.48]) was the most influential, while the vaccine production process (coordinates C: [2.43, -.98]) was the most influenced component in the interactive model. Conclusion: The process of designing and manufacturing vaccines involves various factors that can either hinder or facilitate progress. Understanding these factors is crucial for effective health system management, policymaking, and fostering innovation in the development and introduction of new vaccines. [ABSTRACT FROM AUTHOR] |
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| Database: | Biomedical Index |
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