Zobrazit v EDS

Corticotropin‐releasing hormone and obesity: From fetal life to adulthood.

Uloženo v:
Podrobná bibliografie
Název: Corticotropin‐releasing hormone and obesity: From fetal life to adulthood.
Autoři: Vasconcelos, Inês, von Hafe, Madalena, Adão, Rui, Leite‐Moreira, Adelino, Brás‐Silva, Carmen
Zdroj: Obesity Reviews; Aug2024, Vol. 25 Issue 8, p1-10, 10p
Témata: CORTICOTROPIN releasing hormone, OBESITY, ADULTS, NEUROPEPTIDES, GENETIC variation, METABOLIC disorders
Abstrakt: Summary: Obesity is among the most common chronic disorders, worldwide. It is a complex disease that reflects the interactions between environmental influences, multiple genetic allelic variants, and behavioral factors. Recent developments have also shown that biological conditions in utero play an important role in the programming of energy homeostasis systems and might have an impact on obesity and metabolic disease risk. The corticotropin‐releasing hormone (CRH) family of neuropeptides, as a central element of energy homeostasis, has been evaluated for its role in the pathophysiology of obesity. This review aims to summarize the relevance and effects of the CRH family of peptides in the pathophysiology of obesity spanning from fetal life to adulthood. [ABSTRACT FROM AUTHOR]
Copyright of Obesity Reviews is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Databáze: Complementary Index
Popis
Abstrakt:Summary: Obesity is among the most common chronic disorders, worldwide. It is a complex disease that reflects the interactions between environmental influences, multiple genetic allelic variants, and behavioral factors. Recent developments have also shown that biological conditions in utero play an important role in the programming of energy homeostasis systems and might have an impact on obesity and metabolic disease risk. The corticotropin‐releasing hormone (CRH) family of neuropeptides, as a central element of energy homeostasis, has been evaluated for its role in the pathophysiology of obesity. This review aims to summarize the relevance and effects of the CRH family of peptides in the pathophysiology of obesity spanning from fetal life to adulthood. [ABSTRACT FROM AUTHOR]
ISSN:14677881
DOI:10.1111/obr.13763