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Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis.

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Název: Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis.
Autoři: Jeon, Keuna, Asuncion, Justin Andrei, Corbett, Alexander Lucien, Yuan, Tiange, Patel, Meera, Andoy, Nesha May Octavio, Kreis, Christian Titus, Voznyy, Oleksandr, Sullan, Ruby May Arana
Zdroj: Nanomaterials (2079-4991); Jun2022, Vol. 12 Issue 12, p2027-N.PAG, 10p
Témata: NANOPARTICLES, DENSITY functional theory, SEROTONIN receptors, SURFACE coatings, SURFACE properties
Abstrakt: Polyserotonin nanoparticles (PSeNP) and films are bioinspired nanomaterials that have potential in biomedical applications and surface coatings. As studies on polyserotonin (PSe) nanoparticles and films are still in their infancy, synthetic pathways and material development for this new class of nanomaterial await investigation. Here, we sought to determine how different buffers used during the polymerization of serotonin to form nanoparticles and films impact the physicochemical properties of PSe materials. We show that buffer components are incorporated into the polymer matrix, which is also supported by density functional theory calculations. While we observed no significant differences between the elasticity of nanoparticles synthesized in the different buffers, the nanoscale surface properties of PSe films revealed dissimilarities in surface functional groups influenced by solvent molecules. Overall, the results obtained in this work can be used towards the rational design of PSe nanomaterials with tailored properties and for specific applications. [ABSTRACT FROM AUTHOR]
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Databáze: Complementary Index
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Abstrakt:Polyserotonin nanoparticles (PSeNP) and films are bioinspired nanomaterials that have potential in biomedical applications and surface coatings. As studies on polyserotonin (PSe) nanoparticles and films are still in their infancy, synthetic pathways and material development for this new class of nanomaterial await investigation. Here, we sought to determine how different buffers used during the polymerization of serotonin to form nanoparticles and films impact the physicochemical properties of PSe materials. We show that buffer components are incorporated into the polymer matrix, which is also supported by density functional theory calculations. While we observed no significant differences between the elasticity of nanoparticles synthesized in the different buffers, the nanoscale surface properties of PSe films revealed dissimilarities in surface functional groups influenced by solvent molecules. Overall, the results obtained in this work can be used towards the rational design of PSe nanomaterials with tailored properties and for specific applications. [ABSTRACT FROM AUTHOR]
ISSN:20794991
DOI:10.3390/nano12122027