View in EDS

Sustained social participation and dementia: evidence from a Japanese longitudinal cohort study with a time-varying exposure analysis.

Saved in:
Bibliographic Details
Title: Sustained social participation and dementia: evidence from a Japanese longitudinal cohort study with a time-varying exposure analysis.
Authors: Matsuyama Y; Department of Dental Public Health, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Bunkyo-ku, Japan. Electronic address: matsuyama-thk@umin.org., Shirai K; Department of Social Medicine and Behavioral Science, Division of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan., Aida J; Department of Dental Public Health, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Bunkyo-ku, Japan; Center for Well-being Research Advancement, Institute of Science Tokyo, Bunkyo-ku, Japan.
Source: Social science & medicine (1982) [Soc Sci Med] 2025 Nov; Vol. 385, pp. 118608. Date of Electronic Publication: 2025 Sep 22.
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Pergamon Country of Publication: England NLM ID: 8303205 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5347 (Electronic) Linking ISSN: 02779536 NLM ISO Abbreviation: Soc Sci Med Subsets: MEDLINE
Imprint Name(s): Original Publication: Oxford ; New York : Pergamon, c1982-
MeSH Terms: Dementia*/epidemiology , Dementia*/psychology , Dementia*/prevention & control , Social Participation*/psychology, Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Cohort Studies ; Japan/epidemiology ; Longitudinal Studies ; Surveys and Questionnaires ; East Asian People/psychology
Abstract: Competing Interests: Declaration of competing interest The authors declare no conflict of interest in relation to this study.
Social participation is linked to a reduced risk of cognitive impairment and dementia. However, few studies have considered the bidirectional relationship between social participation and cognitive decline over time. We aimed to estimate the effect of sustained social participation on dementia risk reduction among older Japanese adults, accounting for the bias induced by the bidirectional relationship. A longitudinal study was conducted using data from the Japan Gerontological Evaluation Study. A baseline survey was administered in 2013, with dementia onset information up to 2022 obtained from the municipality registry (n = 47,698; median follow-up 9.2 years). Additional questionnaire surveys in 2016 and 2019 collected data on social participation and time-varying confounders. The average treatment effect (ATE) of sustained social participation on dementia onset was estimated using doubly robust targeted minimum loss-based estimation. Of the participants, 17.2 % got dementia. Participants with baseline social participation had a lower incidence of dementia (14.7 %) compared to those without social participation (17.8 %). Sustained social participation in any group at least once per week from 2013 to 2019 was associated with a 3.2 percentage point increase in dementia-free survival probability (95 % confidence interval, CI: 1.9, 4.5) compared to never participated. Among specific group types, participation in sports groups (ATE = 4.2; 95 % CI: 2.0, 6.4) and hobby groups (ATE = 5.3; 95 % CI: 2.5, 8.0) was significantly associated with increased dementia-free survival probability. Sustained social participation was associated with reduced dementia risk among older Japanese adults.
(Copyright © 2025 Elsevier Ltd. All rights reserved.)
Contributed Indexing: Keywords: Biostatistics; Dementia; Older people; Social determinants of health; Social participation
Entry Date(s): Date Created: 20250928 Date Completed: 20251017 Latest Revision: 20251118
Update Code: 20251118
DOI: 10.1016/j.socscimed.2025.118608
PMID: 41016361
Database: MEDLINE
Description
Abstract:Competing Interests: Declaration of competing interest The authors declare no conflict of interest in relation to this study.<br />Social participation is linked to a reduced risk of cognitive impairment and dementia. However, few studies have considered the bidirectional relationship between social participation and cognitive decline over time. We aimed to estimate the effect of sustained social participation on dementia risk reduction among older Japanese adults, accounting for the bias induced by the bidirectional relationship. A longitudinal study was conducted using data from the Japan Gerontological Evaluation Study. A baseline survey was administered in 2013, with dementia onset information up to 2022 obtained from the municipality registry (n = 47,698; median follow-up 9.2 years). Additional questionnaire surveys in 2016 and 2019 collected data on social participation and time-varying confounders. The average treatment effect (ATE) of sustained social participation on dementia onset was estimated using doubly robust targeted minimum loss-based estimation. Of the participants, 17.2 % got dementia. Participants with baseline social participation had a lower incidence of dementia (14.7 %) compared to those without social participation (17.8 %). Sustained social participation in any group at least once per week from 2013 to 2019 was associated with a 3.2 percentage point increase in dementia-free survival probability (95 % confidence interval, CI: 1.9, 4.5) compared to never participated. Among specific group types, participation in sports groups (ATE = 4.2; 95 % CI: 2.0, 6.4) and hobby groups (ATE = 5.3; 95 % CI: 2.5, 8.0) was significantly associated with increased dementia-free survival probability. Sustained social participation was associated with reduced dementia risk among older Japanese adults.<br /> (Copyright © 2025 Elsevier Ltd. All rights reserved.)
ISSN:1873-5347
DOI:10.1016/j.socscimed.2025.118608