Moderating effects of self-defined sexual orientation on the relation between social factors and depressive symptoms or suicidal ideation among French young adults.

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Název: Moderating effects of self-defined sexual orientation on the relation between social factors and depressive symptoms or suicidal ideation among French young adults.
Autoři: Kose J; Université Paris-Saclay, Inserm, Université Versailles Saint-Quentin (UVSQ), Centre d'Epidémiologie et de Santé Publique (CESP), Paris, France. junko.kose@inserm.fr., Davisse-Paturet C; Social Epidemiology Research Team, Institut Pierre Louis d'Epidémiologie Et de Santé Publique (IPLESP), Université, InsermParis, Sorbonne, France., Pastorello A; Université Paris-Saclay, Inserm, Université Versailles Saint-Quentin (UVSQ), Centre d'Epidémiologie et de Santé Publique (CESP), Paris, France., Meyer L; Université Paris-Saclay, Inserm, Université Versailles Saint-Quentin (UVSQ), Centre d'Epidémiologie et de Santé Publique (CESP), Paris, France.; Epidemiology and Public Health Department, Assistance Publique-Hôpitaux de Paris Université Paris-Saclay, Le Kremlin-Bicêtre, France., Melchior M; Social Epidemiology Research Team, Institut Pierre Louis d'Epidémiologie Et de Santé Publique (IPLESP), Université, InsermParis, Sorbonne, France., Vuillermoz C; Université Paris-Saclay, Inserm, Université Versailles Saint-Quentin (UVSQ), Centre d'Epidémiologie et de Santé Publique (CESP), Paris, France., Rouquette A; Université Paris-Saclay, Inserm, Université Versailles Saint-Quentin (UVSQ), Centre d'Epidémiologie et de Santé Publique (CESP), Paris, France.; Epidemiology and Public Health Department, Assistance Publique-Hôpitaux de Paris Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Korporace: EpiCov Study Group
Zdroj: Social psychiatry and psychiatric epidemiology [Soc Psychiatry Psychiatr Epidemiol] 2025 Oct; Vol. 60 (10), pp. 2455-2468. Date of Electronic Publication: 2025 Jun 23.
Způsob vydávání: Journal Article
Jazyk: English
Informace o časopise: Publisher: Springer International Country of Publication: Germany NLM ID: 8804358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-9285 (Electronic) Linking ISSN: 09337954 NLM ISO Abbreviation: Soc Psychiatry Psychiatr Epidemiol Subsets: MEDLINE
Imprint Name(s): Original Publication: [Berlin] : Springer International, [c1988-
Výrazy ze slovníku MeSH: Suicidal Ideation* , Depression*/epidemiology , Depression*/psychology , Sexual and Gender Minorities*/psychology , Sexual and Gender Minorities*/statistics & numerical data , Sexual Behavior*/psychology , Sexual Behavior*/statistics & numerical data, Humans ; Male ; Female ; France/epidemiology ; Cross-Sectional Studies ; Adult ; Young Adult ; Adolescent ; Prevalence ; Social Factors ; Risk Factors
Abstrakt: Competing Interests: Declaration. Conflict of interest: The authors declare no competing interest. Ethics statement: The studies involving human participants were reviewed and approved by Comité de Protection des Personnes Sud Méditerranée III 2020- A0119138 and France’s National Data Protection Agency (Commission Nationale Informatique et Libertés, CNIL, MLD/MFI/AR205138). The patients/participants provided their written informed consent to participate in this study.
Purpose: Disparities in mental health across sexual orientation groups and among young adults have long been discussed. The aim of this cross-sectional study was to investigate the moderating effects of sexual orientation on the associations between social factors and depressive symptoms as well as suicidal ideation in young adults.
Methods: The study included 6,337 participants aged 18-25y in 2022 from the French EpiCov cohort. The outcome variables were depressive symptoms and suicidal ideation. Poisson regressions with robust error variance were performed to investigate the associations between social factors and outcomes according to sexual orientation (lesbian, gay, bisexual, other, or not defining themselves according to their sexuality: sexual minority (SM); heterosexual or not wishing to answer: Not belonging to SM (NSM)).
Results: The prevalence of depressive symptoms and suicidal ideation was higher in the SM than in the NSM group. Regarding depressive symptoms, significant moderating effects of sexual orientation were observed for female vs male sex (NSM: adjusted Prevalence Ratio (aPR) 1.58[1.28-1.95], SM: aPR 1.03[0.78-1.36]) and age category 22-25y vs 18-21y (NSM: aPR 1.32[1.05-1.67], SM: aPR 0.78[0.59-1.03]). Regarding suicidal ideation, significant moderating effect was observed for not being vs being in a relationship (NSM: aPR 1.55[1.14-2.12], SM: aPR 0.82[0.59-1.13]).
Conclusion: In this study conducted in 2022, well-known social risk factors of mental problems do not explain the higher prevalence of depressive symptoms and suicidal ideation among young SM group. Further studies are needed to understand the specific challenges faced by these young people.
(© 2025. The Author(s).)
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Contributed Indexing: Investigator: J Warszawski; N Bajos; G Bagein; F Beck; E Counil; F Jusot; N Lydié; C Martin; P Raynaud; A Pailhé; D Rahib; P Sillard; A Spire
Keywords: Depressive symptoms; Epidemiology; Sexual orientation; Social factors; Suicidal ideation; Young adults
Entry Date(s): Date Created: 20250623 Date Completed: 20250920 Latest Revision: 20250922
Update Code: 20250922
PubMed Central ID: PMC12449324
DOI: 10.1007/s00127-025-02951-y
PMID: 40548974
Databáze: MEDLINE
Popis
Abstrakt:Competing Interests: Declaration. Conflict of interest: The authors declare no competing interest. Ethics statement: The studies involving human participants were reviewed and approved by Comité de Protection des Personnes Sud Méditerranée III 2020- A0119138 and France’s National Data Protection Agency (Commission Nationale Informatique et Libertés, CNIL, MLD/MFI/AR205138). The patients/participants provided their written informed consent to participate in this study.<br />Purpose: Disparities in mental health across sexual orientation groups and among young adults have long been discussed. The aim of this cross-sectional study was to investigate the moderating effects of sexual orientation on the associations between social factors and depressive symptoms as well as suicidal ideation in young adults.<br />Methods: The study included 6,337 participants aged 18-25y in 2022 from the French EpiCov cohort. The outcome variables were depressive symptoms and suicidal ideation. Poisson regressions with robust error variance were performed to investigate the associations between social factors and outcomes according to sexual orientation (lesbian, gay, bisexual, other, or not defining themselves according to their sexuality: sexual minority (SM); heterosexual or not wishing to answer: Not belonging to SM (NSM)).<br />Results: The prevalence of depressive symptoms and suicidal ideation was higher in the SM than in the NSM group. Regarding depressive symptoms, significant moderating effects of sexual orientation were observed for female vs male sex (NSM: adjusted Prevalence Ratio (aPR) 1.58[1.28-1.95], SM: aPR 1.03[0.78-1.36]) and age category 22-25y vs 18-21y (NSM: aPR 1.32[1.05-1.67], SM: aPR 0.78[0.59-1.03]). Regarding suicidal ideation, significant moderating effect was observed for not being vs being in a relationship (NSM: aPR 1.55[1.14-2.12], SM: aPR 0.82[0.59-1.13]).<br />Conclusion: In this study conducted in 2022, well-known social risk factors of mental problems do not explain the higher prevalence of depressive symptoms and suicidal ideation among young SM group. Further studies are needed to understand the specific challenges faced by these young people.<br /> (© 2025. The Author(s).)
ISSN:1433-9285
DOI:10.1007/s00127-025-02951-y