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    Authors: Wang Z Li A Xu W et al.

    Source: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2025 Sep 15; Vol. 39 (17), pp. e10073.

    Publication Type: Journal Article

    Journal Info: Publisher: John Wiley And Sons Ltd Country of Publication: England NLM ID: 8802365 Publication Model: Print Cited Medium: Internet ISSN: 1097-0231 (Electronic) Linking ISSN: 09514198 NLM ISO Abbreviation: Rapid Commun Mass Spectrom Subsets: PubMed not MEDLINE; MEDLINE

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    Contributors: Patrick Bergman, Assostand Professor

    Source: Design of an Intelligent Wearable to Assess Physical Activity and Health Related Outcomes - the DIWAH Study
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    Wright SP, Hall Brown TS, Collier SR, Sandberg K. How consumer physical activity monitors could transform human physiology research. Am J Physiol Regul Integr Comp Physiol. 2017 Mar 1;312(3):R358-R367. doi: 10.1152/ajpregu.00349.2016. Epub 2017 Jan 4.
    Hosanee M, Chan G, Welykholowa K, Cooper R, Kyriacou PA, Zheng D, Allen J, Abbott D, Menon C, Lovell NH, Howard N, Chan WS, Lim K, Fletcher R, Ward R, Elgendi M. Cuffless Single-Site Photoplethysmography for Blood Pressure Monitoring. J Clin Med. 2020 Mar 7;9(3):723. doi: 10.3390/jcm9030723.
    Aromatario O, Van Hoye A, Vuillemin A, Foucaut AM, Crozet C, Pommier J, Cambon L. How do mobile health applications support behaviour changes? A scoping review of mobile health applications relating to physical activity and eating behaviours. Public Health. 2019 Oct;175:8-18. doi: 10.1016/j.puhe.2019.06.011. Epub 2019 Jul 30.
    Bayoumy K, Gaber M, Elshafeey A, Mhaimeed O, Dineen EH, Marvel FA, Martin SS, Muse ED, Turakhia MP, Tarakji KG, Elshazly MB. Smart wearable devices in cardiovascular care: where we are and how to move forward. Nat Rev Cardiol. 2021 Aug;18(8):581-599. doi: 10.1038/s41569-021-00522-7. Epub 2021 Mar 4.
    Greiwe J, Nyenhuis SM. Wearable Technology and How This Can Be Implemented into Clinical Practice. Curr Allergy Asthma Rep. 2020 Jun 6;20(8):36. doi: 10.1007/s11882-020-00927-3.
    Peake JM, Kerr G, Sullivan JP. A Critical Review of Consumer Wearables, Mobile Applications, and Equipment for Providing Biofeedback, Monitoring Stress, and Sleep in Physically Active Populations. Front Physiol. 2018 Jun 28;9:743. doi: 10.3389/fphys.2018.00743. eCollection 2018.
    Bergman P. The number of repeated observations needed to estimate the habitual physical activity of an individual to a given level of precision. PLoS One. 2018 Feb 1;13(2):e0192117. doi: 10.1371/journal.pone.0192117. eCollection 2018.
    Bergman P, Hagstromer M. No one accelerometer-based physical activity data collection protocol can fit all research questions. BMC Med Res Methodol. 2020 Jun 3;20(1):141. doi: 10.1186/s12874-020-01026-7.
    Jensen MT, Treskes RW, Caiani EG, Casado-Arroyo R, Cowie MR, Dilaveris P, Duncker D, Di Rienzo M, Frederix I, De Groot N, Kolh PH, Kemps H, Mamas M, McGreavy P, Neubeck L, Parati G, Platonov PG, Schmidt-Trucksass A, Schuuring MJ, Simova I, Svennberg E, Verstrael A, Lumens J. ESC working group on e-cardiology position paper: use of commercially available wearable technology for heart rate and activity tracking in primary and secondary cardiovascular prevention-in collaboration with the European Heart Rhythm Association, European Association of Preventive Cardiology, Association of Cardiovascular Nursing and Allied Professionals, Patient Forum, and the Digital Health Committee. Eur Heart J Digit Health. 2021 Feb 8;2(1):49-59. doi: 10.1093/ehjdh/ztab011. eCollection 2021 Mar.
    Wong CK, Mentis HM, Kuber R. The bit doesn't fit: Evaluation of a commercial activity-tracker at slower walking speeds. Gait Posture. 2018 Jan;59:177-181. doi: 10.1016/j.gaitpost.2017.10.010. Epub 2017 Oct 9.
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    Keadle SK, Lyden KA, Strath SJ, Staudenmayer JW, Freedson PS. A Framework to Evaluate Devices That Assess Physical Behavior. Exerc Sport Sci Rev. 2019 Oct;47(4):206-214. doi: 10.1249/JES.0000000000000206.
    Muhlen JM, Stang J, Lykke Skovgaard E, Judice PB, Molina-Garcia P, Johnston W, Sardinha LB, Ortega FB, Caulfield B, Bloch W, Cheng S, Ekelund U, Brond JC, Grontved A, Schumann M. Recommendations for determining the validity of consumer wearable heart rate devices: expert statement and checklist of the INTERLIVE Network. Br J Sports Med. 2021 Jul;55(14):767-779. doi: 10.1136/bjsports-2020-103148. Epub 2021 Jan 4.
    Gillinov S, Etiwy M, Wang R, Blackburn G, Phelan D, Gillinov AM, Houghtaling P, Javadikasgari H, Desai MY. Variable Accuracy of Wearable Heart Rate Monitors during Aerobic Exercise. Med Sci Sports Exerc. 2017 Aug;49(8):1697-1703. doi: 10.1249/MSS.0000000000001284.
    Oja, P. & Tuxworth, B. Eurofit for adults. Assessment of health-related fitness. Strasbourg: Council of Europe-UKK Institute, Tampere. (1995).
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    Westerterp KR. Doubly labelled water assessment of energy expenditure: principle, practice, and promise. Eur J Appl Physiol. 2017 Jul;117(7):1277-1285. doi: 10.1007/s00421-017-3641-x. Epub 2017 May 15.
    Arvidsson D, Fridolfsson J, Borjesson M. Measurement of physical activity in clinical practice using accelerometers. J Intern Med. 2019 Aug;286(2):137-153. doi: 10.1111/joim.12908. Epub 2019 Apr 16.
    Liu F, Wanigatunga AA, Schrack JA. Assessment of Physical Activity in Adults Using Wrist Accelerometers. Epidemiol Rev. 2022 Jan 14;43(1):65-93. doi: 10.1093/epirev/mxab004.
    Rastogi T, Backes A, Schmitz S, Fagherazzi G, van Hees V, Malisoux L. Advanced analytical methods to assess physical activity behaviour using accelerometer raw time series data: a protocol for a scoping review. Syst Rev. 2020 Nov 7;9(1):259. doi: 10.1186/s13643-020-01515-2.
    Garatachea N, Torres Luque G, Gonzalez Gallego J. Physical activity and energy expenditure measurements using accelerometers in older adults. Nutr Hosp. 2010 Mar-Apr;25(2):224-30.
    Heesch KC, Hill RL, Aguilar-Farias N, van Uffelen JGZ, Pavey T. Validity of objective methods for measuring sedentary behaviour in older adults: a systematic review. Int J Behav Nutr Phys Act. 2018 Nov 26;15(1):119. doi: 10.1186/s12966-018-0749-2.
    Phillips LJ, Petroski GF, Markis NE. A Comparison of Accelerometer Accuracy in Older Adults. Res Gerontol Nurs. 2015 Sep-Oct;8(5):213-9. doi: 10.3928/19404921-20150429-03. Epub 2015 May 7.
    Sheng, B., Moosman, O. M., Del Pozo-Cruz, B., Del Pozo-Cruz, J., Alfonso-Rosa, R. M. & Zhang, Y. A comparison of different machine learning algorithms, types and placements of activity monitors for physical activity classification. Measurement 154, 107480 (2020).
    Montoye AHK, Pivarnik JM, Mudd LM, Biswas S, Pfeiffer KA. Validation and Comparison of Accelerometers Worn on the Hip, Thigh, and Wrists for Measuring Physical Activity and Sedentary Behavior. AIMS Public Health. 2016 May 20;3(2):298-312. doi: 10.3934/publichealth.2016.2.298. eCollection 2016.
    Montoye AHK, Westgate BS, Fonley MR, Pfeiffer KA. Cross-validation and out-of-sample testing of physical activity intensity predictions with a wrist-worn accelerometer. J Appl Physiol (1985). 2018 May 1;124(5):1284-1293. doi: 10.1152/japplphysiol.00760.2017. Epub 2018 Jan 25.
    Ahmadi MN, Chowdhury A, Pavey T, Trost SG. Laboratory-based and free-living algorithms for energy expenditure estimation in preschool children: A free-living evaluation. PLoS One. 2020 May 20;15(5):e0233229. doi: 10.1371/journal.pone.0233229. eCollection 2020.
    Stewart T, Narayanan A, Hedayatrad L, Neville J, Mackay L, Duncan S. A Dual-Accelerometer System for Classifying Physical Activity in Children and Adults. Med Sci Sports Exerc. 2018 Dec;50(12):2595-2602. doi: 10.1249/MSS.0000000000001717.
    Willetts M, Hollowell S, Aslett L, Holmes C, Doherty A. Statistical machine learning of sleep and physical activity phenotypes from sensor data in 96,220 UK Biobank participants. Sci Rep. 2018 May 21;8(1):7961. doi: 10.1038/s41598-018-26174-1.
    Narayanan A, Desai F, Stewart T, Duncan S, Mackay L. Application of Raw Accelerometer Data and Machine-Learning Techniques to Characterize Human Movement Behavior: A Systematic Scoping Review. J Phys Act Health. 2020 Mar 1;17(3):360-383. doi: 10.1123/jpah.2019-0088.
    Galán-Mercant, A., Ortiz, A., Herrera-Viedma, E., Tomas, M. T., Fernandes, B. & Moral-Munoz, J. A. Assessing physical activity and functional fitness level using convolutional neural networks. Knowledge-Based Systems 185 (2019).
    Hamid A, Duncan MJ, Eyre ELJ, Jing Y. Predicting children's energy expenditure during physical activity using deep learning and wearable sensor data. Eur J Sport Sci. 2021 Jun;21(6):918-926. doi: 10.1080/17461391.2020.1789749. Epub 2020 Jul 16.
    van Kuppevelt D, Heywood J, Hamer M, Sabia S, Fitzsimons E, van Hees V. Segmenting accelerometer data from daily life with unsupervised machine learning. PLoS One. 2019 Jan 9;14(1):e0208692. doi: 10.1371/journal.pone.0208692. eCollection 2019.
    Jones PJ, Catt M, Davies MJ, Edwardson CL, Mirkes EM, Khunti K, Yates T, Rowlands AV. Feature selection for unsupervised machine learning of accelerometer data physical activity clusters - A systematic review. Gait Posture. 2021 Oct;90:120-128. doi: 10.1016/j.gaitpost.2021.08.007. Epub 2021 Aug 13.
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    Source: Modifiers of Disease Severity and Progression in Cerebral Cavernous Malformations
    Akers AL, Ball KL, Clancy M, Comi AM, Faughnan ME, Gopal-Srivastava R, Jacobs TP, Kim H, Krischer J, Marchuk DA, McCulloch CE, Morrison L, Moses M, Moy CS, Pawlikowska L, Young WL. Brain Vascular Malformation Consortium: Overview, Progress and Future Directions. J Rare Disord. 2013 Apr 1;1(1):5.
    Flemming KD, Smith E, Marchuk D, Derry WB. Familial Cerebral Cavernous Malformations. 2003 Feb 24 [updated 2023 Jul 27]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews(R) [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2025. Available from http://www.ncbi.nlm.nih.gov/books/NBK1293/
    Choquet H, Pawlikowska L, Lawton MT, Kim H. Genetics of cerebral cavernous malformations: current status and future prospects. J Neurosurg Sci. 2015 Sep;59(3):211-20. Epub 2015 Apr 22.
    Zafar A, Quadri SA, Farooqui M, Ikram A, Robinson M, Hart BL, Mabray MC, Vigil C, Tang AT, Kahn ML, Yonas H, Lawton MT, Kim H, Morrison L. Familial Cerebral Cavernous Malformations. Stroke. 2019 May;50(5):1294-1301. doi: 10.1161/STROKEAHA.118.022314. No abstract available.
    Hart BL, Mabray MC, Morrison L, Whitehead KJ, Kim H. Systemic and CNS manifestations of inherited cerebrovascular malformations. Clin Imaging. 2021 Jul;75:55-66. doi: 10.1016/j.clinimag.2021.01.020. Epub 2021 Jan 20.
    Choquet H, Pawlikowska L, Nelson J, McCulloch CE, Akers A, Baca B, Khan Y, Hart B, Morrison L, Kim H; Brain Vascular Malformation Consortium (BVMC) Study. Polymorphisms in inflammatory and immune response genes associated with cerebral cavernous malformation type 1 severity. Cerebrovasc Dis. 2014;38(6):433-40. doi: 10.1159/000369200. Epub 2014 Dec 3.
    Choquet H, Nelson J, Pawlikowska L, McCulloch CE, Akers A, Baca B, Khan Y, Hart B, Morrison L, Kim H. Association of cardiovascular risk factors with disease severity in cerebral cavernous malformation type 1 subjects with the common Hispanic mutation. Cerebrovasc Dis. 2014;37(1):57-63. doi: 10.1159/000356839. Epub 2013 Dec 21.
    Golden M, Saeidi S, Liem B, Marchand E, Morrison L, Hart B. Sensitivity of patients with familial cerebral cavernous malformations to therapeutic radiation. J Med Imaging Radiat Oncol. 2015 Feb;59(1):134-6. doi: 10.1111/1754-9485.12269. Epub 2015 Jan 7.
    Hart BL, Taheri S, Rosenberg GA, Morrison LA. Dynamic contrast-enhanced MRI evaluation of cerebral cavernous malformations. Transl Stroke Res. 2013 Oct;4(5):500-6. doi: 10.1007/s12975-013-0285-y. Epub 2013 Sep 21.
    Petersen TA, Morrison LA, Schrader RM, Hart BL. Familial versus sporadic cavernous malformations: differences in developmental venous anomaly association and lesion phenotype. AJNR Am J Neuroradiol. 2010 Feb;31(2):377-82. doi: 10.3174/ajnr.A1822. Epub 2009 Oct 15.
    Choquet H, Trapani E, Goitre L, Trabalzini L, Akers A, Fontanella M, Hart BL, Morrison LA, Pawlikowska L, Kim H, Retta SF. Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1. Free Radic Biol Med. 2016 Mar;92:100-109. doi: 10.1016/j.freeradbiomed.2016.01.008. Epub 2016 Jan 19.
    Golden MJ, Morrison LA, Kim H, Hart BL. Increased number of white matter lesions in patients with familial cerebral cavernous malformations. AJNR Am J Neuroradiol. 2015 May;36(5):899-903. doi: 10.3174/ajnr.A4200. Epub 2015 Jan 2.
    Zou X, Hart BL, Mabray M, Bartlett MR, Bian W, Nelson J, Morrison LA, McCulloch CE, Hess CP, Lupo JM, Kim H. Automated algorithm for counting microbleeds in patients with familial cerebral cavernous malformations. Neuroradiology. 2017 Jul;59(7):685-690. doi: 10.1007/s00234-017-1845-8. Epub 2017 May 22.
    Strickland CD, Eberhardt SC, Bartlett MR, Nelson J, Kim H, Morrison LA, Hart BL. Familial Cerebral Cavernous Malformations Are Associated with Adrenal Calcifications on CT Scans: An Imaging Biomarker for a Hereditary Cerebrovascular Condition. Radiology. 2017 Aug;284(2):443-450. doi: 10.1148/radiol.2017161127. Epub 2017 Mar 20.
    Akers A, Al-Shahi Salman R, A Awad I, Dahlem K, Flemming K, Hart B, Kim H, Jusue-Torres I, Kondziolka D, Lee C, Morrison L, Rigamonti D, Rebeiz T, Tournier-Lasserve E, Waggoner D, Whitehead K. Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel. Neurosurgery. 2017 May 1;80(5):665-680. doi: 10.1093/neuros/nyx091.
    Tang AT, Choi JP, Kotzin JJ, Yang Y, Hong CC, Hobson N, Girard R, Zeineddine HA, Lightle R, Moore T, Cao Y, Shenkar R, Chen M, Mericko P, Yang J, Li L, Tanes C, Kobuley D, Vosa U, Whitehead KJ, Li DY, Franke L, Hart B, Schwaninger M, Henao-Mejia J, Morrison L, Kim H, Awad IA, Zheng X, Kahn ML. Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature. 2017 May 18;545(7654):305-310. doi: 10.1038/nature22075. Epub 2017 May 10.
    Morrison MA, Payabvash S, Chen Y, Avadiappan S, Shah M, Zou X, Hess CP, Lupo JM. A user-guided tool for semi-automated cerebral microbleed detection and volume segmentation: Evaluating vascular injury and data labelling for machine learning. Neuroimage Clin. 2018 Aug 4;20:498-505. doi: 10.1016/j.nicl.2018.08.002. eCollection 2018.
    Mabray MC, Caprihan A, Nelson J, McCulloch CE, Zafar A, Kim H, Hart BL, Morrison L. Effect of Simvastatin on Permeability in Cerebral Cavernous Malformation Type 1 Patients: Results from a Pilot Small Randomized Controlled Clinical Trial. Transl Stroke Res. 2020 Jun;11(3):319-321. doi: 10.1007/s12975-019-00737-4. Epub 2019 Oct 23. No abstract available.
    Tang AT, Sullivan KR, Hong CC, Goddard LM, Mahadevan A, Ren A, Pardo H, Peiper A, Griffin E, Tanes C, Mattei LM, Yang J, Li L, Mericko-Ishizuka P, Shen L, Hobson N, Girard R, Lightle R, Moore T, Shenkar R, Polster SP, Rodel CJ, Li N, Zhu Q, Whitehead KJ, Zheng X, Akers A, Morrison L, Kim H, Bittinger K, Lengner CJ, Schwaninger M, Velcich A, Augenlicht L, Abdelilah-Seyfried S, Min W, Marchuk DA, Awad IA, Kahn ML. Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation. Sci Transl Med. 2019 Nov 27;11(520):eaaw3521. doi: 10.1126/scitranslmed.aaw3521.
    Tandberg SR, Bocklage T, Bartlett MR, Morrison LA, Nelson J, Hart BL. Vertebral Intraosseous Vascular Malformations in a Familial Cerebral Cavernous Malformation Population: Prevalence, Histologic Features, and Associations With CNS Disease. AJR Am J Roentgenol. 2020 Feb;214(2):428-436. doi: 10.2214/AJR.19.21492. Epub 2019 Dec 11.
    Manole AK, Forrester VJ, Zlotoff BJ, Hart BL, Morrison LA. Cutaneous findings of familial cerebral cavernous malformation syndrome due to the common Hispanic mutation. Am J Med Genet A. 2020 May;182(5):1066-1072. doi: 10.1002/ajmg.a.61519. Epub 2020 Feb 26.
    Campbell R, Petranovich CL, Cheek S, Morrison L, Hart B. Subjective Cognitive Concerns and Attitudes toward Genetic Testing Are Associated with Depressive Symptoms and Quality of Life after Genetic Testing for the Cerebral Cavernous Malformation Common Hispanic Mutation (CCM1). J Behav Brain Sci. 2020 Feb;10(2):118-127. doi: 10.4236/jbbs.2020.102007. Epub 2020 Feb 25.
    Mabray MC, Starcevich J, Hallstrom J, Robinson M, Bartlett M, Nelson J, Zafar A, Kim H, Morrison L, Hart BL. High Prevalence of Spinal Cord Cavernous Malformations in the Familial Cerebral Cavernous Malformations Type 1 Cohort. AJNR Am J Neuroradiol. 2020 Jun;41(6):1126-1130. doi: 10.3174/ajnr.A6584. Epub 2020 May 28.
    Polster SP, Sharma A, Tanes C, Tang AT, Mericko P, Cao Y, Carrion-Penagos J, Girard R, Koskimaki J, Zhang D, Stadnik A, Romanos SG, Lyne SB, Shenkar R, Yan K, Lee C, Akers A, Morrison L, Robinson M, Zafar A, Bittinger K, Kim H, Gilbert JA, Kahn ML, Shen L, Awad IA. Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma. Nat Commun. 2020 May 27;11(1):2659. doi: 10.1038/s41467-020-16436-w.
    Weinsheimer S, Nelson J, Abla AA, Ko NU, Tsang C, Okoye O, Zabramski JM, Akers A, Zafar A, Mabray MC, Hart BL, Morrison L, McCulloch CE, Kim H; Brain Vascular Malformation Consortium Cerebral Cavernous Malformation Investigator Group *. Intracranial Hemorrhage Rate and Lesion Burden in Patients With Familial Cerebral Cavernous Malformation. J Am Heart Assoc. 2023 Feb 7;12(3):e027572. doi: 10.1161/JAHA.122.027572. Epub 2023 Jan 25.
    Fox CK, Nelson J, McCulloch CE, Weinsheimer S, Pawlikowska L, Hart B, Mabray MC, Zafar A, Morrison L, Zabramski JM, Akers A, Kim H. Seizure Incidence Rates in Children and Adults With Familial Cerebral Cavernous Malformations. Neurology. 2021 Sep 20;97(12):e1210-e1216. doi: 10.1212/WNL.0000000000012569.
    Choksi F, Weinsheimer S, Nelson J, Pawlikowska L, Fox CK, Zafar A, Mabray MC, Zabramski J, Akers A, Hart BL, Morrison L, McCulloch CE, Kim H. Assessing the association of common genetic variants in EPHB4 and RASA1 with phenotype severity in familial cerebral cavernous malformation. Mol Genet Genomic Med. 2021 Oct;9(10):e1794. doi: 10.1002/mgg3.1794. Epub 2021 Sep 7.
    Wetzel-Strong SE, Weinsheimer S, Nelson J, Pawlikowska L, Clark D, Starr MD, Liu Y, Kim H, Faughnan ME, Nixon AB, Marchuk DA. Pilot investigation of circulating angiogenic and inflammatory biomarkers associated with vascular malformations. Orphanet J Rare Dis. 2021 Sep 3;16(1):372. doi: 10.1186/s13023-021-02009-7.

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