Výsledky vyhledávání - high throughput transcriptome data mining and computational verification

A New Strategy to Identify ceRNA-Based CCDC144NL-AS1/SERPINE1 Regulatory Axis as a Novel Prognostic Biomarker for Stomach Adenocarcinoma via High Throughput Transcriptome Data Mining and Computational Verification

Autoři: Zhihong Huang Xinkui Liu Chao Wu a další

Zdroj: Front Oncol
Frontiers in Oncology, Vol 11 (2022)

Témata: 0301 basic medicine, 03 medical and health sciences, high throughput transcriptome data mining and computational verification, 0302 clinical medicine, CCDC144NL-AS1/SERPINE1 axis, Oncology, stomach adenocarcinoma, competitive endogenous RNA, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, prognostic biomarker, RC254-282, 3. Good health

Přístupová URL adresa: https://www.frontiersin.org/articles/10.3389/fonc.2021.802727/pdf
https://pubmed.ncbi.nlm.nih.gov/35155200
https://doaj.org/article/c55a9f930d40404c956d37c7da74d307

A New Strategy to Identify ceRNA-Based CCDC144NL-AS1/SERPINE1 Regulatory Axis as a Novel Prognostic Biomarker for Stomach Adenocarcinoma via High Throughput Transcriptome Data Mining and Computational Verification.

Autoři: Huang, Zhihong Liu, Xinkui Wu, Chao a další

Zdroj: Frontiers in Oncology; 1/27/2022, Vol. 12, p1-17, 17p

Témata: DATA mining, TRANSCRIPTOMES, STOMACH, PROGNOSIS, ADENOCARCINOMA

Advances in zearalenone-degrading enzymes research: characteristics, mining, improvement, and application.

Autoři: Tang, Yu Chen, Aimin Guo, Yongpeng a další

Zdroj: Journal of Animal Science & Biotechnology. 11/13/2025, Vol. 16 Issue 1, p1-26. 26p.

Multi-omics and AI-driven advances in miRNA-mediated hair follicle regulation in cashmere goats.

Autoři: Chunhua, Zhang Le, Fu Shengli, Li a další

Zdroj: Frontiers in Veterinary Science. 2025, p1-24. 24p.

Non-coding RNA in the gut of the blood-feeding parasitic worm, Haemonchus contortus.

Autoři: Zhou, Caixian Tuersong, Waresi Liu, Lu a další

Zdroj: Veterinary Research. 1/3/2024, Vol. 55 Issue 1, p1-15. 15p.

Témata: Non-coding RNA, Haemonchus contortus, Helminths, RNA analysis, Circular RNA, ATP-binding cassette transporters

Rumen microbiome nutriomics: Harnessing omics technologies for enhanced understanding of rumen microbiome functions and ruminant nutrition.

Autoři: Yu, Zhongtang Yan, Ming Wang, Jiakun

Zdroj: Animal Nutriomics. 2024, Vol. 1, p1-11. 11p.

Inhibition of FGFR2 Signaling by Cynaroside Attenuates Liver Fibrosis.

Autoři: Meng, Qilin Luo, Lin Lei, Minghua a další

Zdroj: Pharmaceuticals (14248247); Apr2023, Vol. 16 Issue 4, p548, 16p

Témata: HEPATIC fibrosis, LIVER cells, FIBROBLAST growth factor 2, FIBROBLAST growth factor receptors, ANIMAL experimentation, NON-alcoholic fatty liver disease

Screening and transcriptomic analysis of anti- Sporothrix globosa targeting AbaA.

Autoři: Wang, Ying Wu, Xiaoyan Fan, Xiyuan a další

Zdroj: Frontiers in Microbiology; 2025, p1-15, 15p

Témata: VIRTUAL high-throughput screening (Drug development), SMALL molecules, MYCOSES, ANIMAL experimentation, SPOROTRICHOSIS

Integrated Drug Mining Reveals Actionable Strategies Inhibiting Plexiform Neurofibromas.

Autoři: Brown, Rebecca M. Farouk Sait, Sameer Dunn, Griffin a další

Zdroj: Brain Sciences (2076-3425); Jun2022, Vol. 12 Issue 6, p720-720, 14p

Témata: NEUROFIBROMA, NEUROFIBROMATOSIS 1, REGULATOR genes, PHARMACODYNAMICS, DATA integrity, MINES & mineral resources, CELL lines

Korporace: UNITED States. Food & Drug Administration

Network Pharmacology-Driven Sustainability: AI and Multi-Omics Synergy for Drug Discovery in Traditional Chinese Medicine.

Autoři: Yang, Lifang Wang, Hanye Zhu, Zhiyao a další

Zdroj: Pharmaceuticals (14248247); Jul2025, Vol. 18 Issue 7, p1074, 25p

Témata: SUSTAINABILITY, ARTIFICIAL intelligence, BIOACTIVE compounds, BIOLOGICAL networks, CHINESE medicine, DRUG discovery, MULTIOMICS

Computer-Aided Drug Design in Research on Chinese Materia Medica: Methods, Applications, Advantages, and Challenges.

Autoři: Chen, Ban Liu, Shuangshuang Xia, Huiyin a další

Zdroj: Pharmaceutics; Mar2025, Vol. 17 Issue 3, p315, 33p

Témata: COMPUTER-assisted drug design, COMPUTATIONAL intelligence, CHINESE medicine, ARTIFICIAL intelligence, MATERIA medica

Development of Microsatellite Markers from Transcriptome of Eriocheir sinensis and Their Application in Multiplex PCR Panels.

Autoři: Xiao, Qizhen Tang, Meijun Li, Qingqing a další

Zdroj: Animals (2076-2615); Nov2024, Vol. 14 Issue 22, p3200, 14p

Témata: CHINESE mitten crab, POPULATION genetics, GENETIC variation, NUCLEOTIDE sequencing, GERMPLASM, MICROSATELLITE repeats

Unlocking the biotechnological potential of Baltic microorganisms.

Autoři: Mazur-Marzec, Hanna Grabowski, Łukasz Węgrzyn, Alicja a další

Zdroj: Frontiers in Microbiology; 2025, p1-25, 25p

Témata: BIOTECHNOLOGY, MICROORGANISMS, BIOACTIVE compounds, ENZYMES, CONVENTION on Biological Diversity (1992), ENVIRONMENTAL remediation, MARINE biotechnology, SEAWATER

Geografický termín: BALTIC Sea

Applications of Machine Learning (ML) and Mathematical Modeling (MM) in Healthcare with Special Focus on Cancer Prognosis and Anticancer Therapy: Current Status and Challenges.

Autoři: Hassan, Jasmin Saeed, Safiya Mohammed Deka, Lipika a další

Zdroj: Pharmaceutics; Feb2024, Vol. 16 Issue 2, p260, 50p

Témata: MACHINE learning, CANCER prognosis, DATA privacy, MATHEMATICAL models, CANCER patient care, MEDICAL care

Integrated Analysis of Differential Expression Profiles of miRNA and mRNA in Gonads of Scatophagus argus Provides New Insights into Sexually Biased Gene Expression.

Autoři: Lei, Yaling Jiao, Kaizhi Huang, Yuanqing a další

Zdroj: Animals (2076-2615); Jun2025, Vol. 15 Issue 11, p1564, 18p

Témata: SEX determination, GENE expression, GENE regulatory networks, SEX differentiation (Embryology), MARICULTURE, GENETIC sex determination, FISH breeding

Mr.Vc v2: An updated version of database with increased data of transcriptome and experimental validated interactions.

Autoři: Zhiyuan Zhang Guozhong Chen Hussain, Wajid a další

Zdroj: Frontiers in Microbiology; 11/22/2022, Vol. 13, p1-10, 10p, 2 Color Photographs, 1 Diagram, 1 Chart, 1 Graph

Protein Bioinformatics Infrastructure for the Integration and Analysis of Multiple High-Throughput "omics" Data.

Autoři: Chuming Chen McGarvey, Peter B. Hongzhan Huang a další

Zdroj: Advances in Bioinformatics; 2010, p1-19, 19p

Témata: BIOINFORMATICS, COMPARATIVE studies, DATA integration, SYSTEM integration, AMINO acid sequence, GENOMICS

Mitophagy related diagnostic biomarkers for coronary in-stent restenosis identified using machine learning and bioinformatics.

Autoři: Shen M Chen M Chen Y a další

Zdroj: Scientific reports [Sci Rep] 2024 Oct 15; Vol. 14 (1), pp. 24137. Date of Electronic Publication: 2024 Oct 15.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Mitophagy*/genetics , Coronary Restenosis*/diagnosis , Coronary Restenosis*/genetics , Coronary Restenosis*/metabolism , Machine Learning* , Biomarkers* , Computational Biology*/methods, Humans ; Percutaneous Coronary Intervention/adverse effects ; Stents/adverse effects ; Gene Expression Profiling ; Coronary Artery Disease/genetics ; Coronary Artery Disease/diagnosis ; Gene Regulatory Networks ; Male

Mining long noncoding RNA in livestock.

Autoři: Weikard, R. Demasius, W. Kuehn, C.

Zdroj: Animal Genetics. Feb2017, Vol. 48 Issue 1, p3-18. 16p.

Identification of critical lncRNAs for milk fat metabolism in dairy cows using WGCNA and the construction of a ceRNAs network.

Autoři: Mu, Tong Hu, Honghong Ma, Yanfen a další

Zdroj: Animal Genetics. Dec2022, Vol. 53 Issue 6, p740-760. 21p.