Výsledky vyhľadávania - "steroids"

Gold nanostars-driven SERS biosensors for fingerprinting detection and quantitative profiling of anabolic steroids.

Autori: Oubu Z Tan R Mu J a ďalší

Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2026 Jan 05; Vol. 344 (Pt 1), pp. 126670. Date of Electronic Publication: 2025 Jul 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE

Výrazy zo slovníka MeSH: Spectrum Analysis, Raman*/methods , Gold*/chemistry , Biosensing Techniques*/methods , Metal Nanoparticles*/chemistry , Anabolic Agents*/analysis , Steroids*/analysis, Limit of Detection ; Doping in Sports ; Humans ; Stanozolol/analysis ; Nandrolone/analysis ; Methandrostenolone/analysis ; Anabolic Androgenic Steroids

Quantitative ¹ H and ¹³ C NMR and Chemometric Assessment of ¹³ C NMR Data: Application to Anabolic Steroid Formulations.

Autori: Balayssac S Assemat G Danoun S a ďalší

Zdroj: Molecules (Basel, Switzerland) [Molecules] 2025 May 06; Vol. 30 (9). Date of Electronic Publication: 2025 May 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anabolic Agents*/chemistry , Anabolic Agents*/analysis , Steroids*/chemistry , Carbon-13 Magnetic Resonance Spectroscopy* , Proton Magnetic Resonance Spectroscopy* , Chemometrics*, Principal Component Analysis ; Magnetic Resonance Spectroscopy/methods ; Cluster Analysis ; Carbon Isotopes ; Anabolic Androgenic Steroids

Anabolic-androgenic steroids are linked to depression and anxiety in male bodybuilders: the hidden psychogenic side of anabolic androgenic steroids.

Autori: Karagun B Altug S

Zdroj: Annals of medicine [Ann Med] 2024 Dec; Vol. 56 (1), pp. 2337717. Date of Electronic Publication: 2024 Apr 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anabolic Androgenic Steroids* , Anabolic Agents*/adverse effects, Humans ; Male ; Young Adult ; Adult ; Cross-Sectional Studies ; Creatinine ; Depression/chemically induced ; Depression/epidemiology ; Testosterone Congeners/adverse effects ; Steroids/adverse effects ; Anxiety/chemically induced ; Estradiol

Research Progress on the Analysis of Anabolic Androgenic Steroids in Biological Samples Based on High Resolution Mass Spectrometry.

Autori: Guo ZS Duan WJ Liu Y a ďalší

Zdroj: Fa yi xue za zhi [Fa Yi Xue Za Zhi] 2024 Dec 25; Vol. 40 (6), pp. 533-541.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Si fa bu si fa jian ding ke xue yan jiu yuan Country of Publication: China NLM ID: 9426151 Publication Model: Print Cited Medium: Internet ISSN: 1004-5619 (Print) Linking ISSN: 10045619 NLM ISO Abbreviation: Fa Yi Xue Za Zhi Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mass Spectrometry*/methods , Anabolic Agents*/analysis , Anabolic Agents*/urine , Anabolic Agents*/metabolism , Substance Abuse Detection*/methods , Androgens*/analysis , Androgens*/urine , Steroids*/analysis, Humans ; Doping in Sports ; Animals ; Gas Chromatography-Mass Spectrometry/methods ; Testosterone Congeners/analysis ; Anabolic Androgenic Steroids

Profiling Multiple Steroid Subclasses Enabled by Rounded Turn SLIM Ion Mobility.

Autori: Frank CL Jones BM Efird E a ďalší

Zdroj: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2025 Dec 03; Vol. 36 (12), pp. 2623-2632. Date of Electronic Publication: 2025 Sep 01.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE

Výrazy zo slovníka MeSH: Steroids*/chemistry , Steroids*/analysis , Steroids*/classification , Ion Mobility Spectrometry*/methods , Ion Mobility Spectrometry*/instrumentation , Mass Spectrometry*/methods, Isomerism

Discovery and development of steroidal enzyme inhibitors as anti-cancer drugs: state-of-the-art and future perspectives.

Autori: Cerra B Gioiello A

Zdroj: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2483818. Date of Electronic Publication: 2025 Apr 02.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Steroids*/pharmacology , Steroids*/chemistry , Steroids*/chemical synthesis , Enzyme Inhibitors*/pharmacology , Enzyme Inhibitors*/chemistry , Enzyme Inhibitors*/chemical synthesis , Drug Discovery* , Drug Development* , Neoplasms*/drug therapy, Humans ; Cell Proliferation/drug effects ; Molecular Structure ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Animals

Structure-Guided Engineering of CYP109B4: From Monooxygenase to Peroxygenase for Selective Steroid Hydroxylation.

Autori: Zhang X Wang Y Jiang X a ďalší

Zdroj: Journal of agricultural and food chemistry [J Agric Food Chem] 2025 Nov 26; Vol. 73 (47), pp. 30417-30428. Date of Electronic Publication: 2025 Nov 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cytochrome P-450 Enzyme System*/chemistry , Cytochrome P-450 Enzyme System*/genetics , Cytochrome P-450 Enzyme System*/metabolism , Steroids*/chemistry , Steroids*/metabolism , Mixed Function Oxygenases*/chemistry , Mixed Function Oxygenases*/genetics , Mixed Function Oxygenases*/metabolism , Bacterial Proteins*/chemistry , Bacterial Proteins*/genetics , Bacterial Proteins*/metabolism, Hydroxylation ; Hydrogen Peroxide/chemistry ; Hydrogen Peroxide/metabolism ; Protein Engineering ; Mutagenesis, Site-Directed ; Biocatalysis ; Kinetics

Synthesis and preliminary biological evaluation of novel steroidal compounds as antibacterial agents.

Autori: Esposito A Stabile M Migliaccio A a ďalší

Zdroj: Steroids [Steroids] 2025 Nov; Vol. 223, pp. 109686. Date of Electronic Publication: 2025 Sep 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0404536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5867 (Electronic) Linking ISSN: 0039128X NLM ISO Abbreviation: Steroids Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemical synthesis , Anti-Bacterial Agents*/chemistry , Steroids*/pharmacology , Steroids*/chemical synthesis , Steroids*/chemistry, Microbial Sensitivity Tests ; Staphylococcus aureus/drug effects ; Humans ; Hemolysis/drug effects ; Acinetobacter baumannii/drug effects ; Structure-Activity Relationship

Marine-Derived Steroids for Cancer Treatment: Search for Potential Selective Glucocorticoid Receptor Agonists/Modulators (SEGRAMs).

Autori: Zhidkova EM Savina ED Yurchenko EA a ďalší

Zdroj: Marine drugs [Mar Drugs] 2025 Oct 14; Vol. 23 (10). Date of Electronic Publication: 2025 Oct 14.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-3397 (Electronic) Linking ISSN: 16603397 NLM ISO Abbreviation: Mar Drugs Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptors, Glucocorticoid*/agonists , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Antineoplastic Agents*/chemistry , Aquatic Organisms*/chemistry , Neoplasms*/drug therapy , Steroids*/pharmacology , Steroids*/therapeutic use , Steroids*/chemistry, Humans ; Animals

Endocannabinoid and steroid hormone levels during and after pregnancy in fingernail samples from mothers and their infants.

Autori: Voegel CD Murari M La Marca-Ghaemmaghami P a ďalší

Zdroj: Steroids [Steroids] 2025 Oct; Vol. 222, pp. 109663. Date of Electronic Publication: 2025 Jul 27.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0404536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5867 (Electronic) Linking ISSN: 0039128X NLM ISO Abbreviation: Steroids Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endocannabinoids*/analysis , Endocannabinoids*/metabolism , Nails*/metabolism , Nails*/chemistry , Steroids*/metabolism , Steroids*/analysis, Humans ; Female ; Pregnancy ; Adult ; Infant, Newborn ; Pilot Projects ; Tandem Mass Spectrometry ; Mothers

Development and Validation of a Patient-Reported Outcome Measure to Assess the Impact of Steroids in the Treatment of Myeloma: The Steroid Symptom Questionnaire-Multiple Myeloma.

Autori: King T Acret L Rutherford C a ďalší

Zdroj: Seminars in oncology nursing [Semin Oncol Nurs] 2025 Oct; Vol. 41 (5), pp. 151943. Date of Electronic Publication: 2025 Jul 02.

Spôsob vydávania: Journal Article; Validation Study; Multicenter Study

Informácie o časopise: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 8504688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3449 (Electronic) Linking ISSN: 07492081 NLM ISO Abbreviation: Semin Oncol Nurs Subsets: MEDLINE

Výrazy zo slovníka MeSH: Multiple Myeloma*/drug therapy , Patient Reported Outcome Measures* , Quality of Life* , Steroids*/therapeutic use , Steroids*/adverse effects, Humans ; Female ; Male ; Middle Aged ; Psychometrics ; Aged ; Surveys and Questionnaires ; Reproducibility of Results ; Aged, 80 and over ; Adult

Polyhydroxy steroids isolated from starfish ( Asterina pectinifera ) and their embryotoxicity.

Autori: Zhang R Lu Z Wang D a ďalší

Zdroj: Natural product research [Nat Prod Res] 2025 Oct; Vol. 39 (19), pp. 5643-5649. Date of Electronic Publication: 2024 May 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Embryo, Nonmammalian*/drug effects , Starfish*/chemistry , Steroids*/chemistry , Steroids*/isolation & purification , Steroids*/toxicity , Asterina*/chemistry , Teratogens*/chemistry , Teratogens*/isolation & purification, Animals ; Molecular Structure ; Oryzias/embryology

Timosaponin AIII from Anemarrhena asphodeloides binds and inhibits S100A8-mediated neutrophil infiltration and NET formation ameliorates MASH.

Autori: Bai Y Ju J Xie R a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 03; Vol. 166, pp. 115539. Date of Electronic Publication: 2025 Sep 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Saponins*/pharmacology , Saponins*/therapeutic use , Anemarrhena*/immunology , Calgranulin A*/metabolism , Extracellular Traps*/drug effects , Extracellular Traps*/metabolism , Extracellular Traps*/immunology , Neutrophils*/drug effects , Neutrophils*/immunology , Fatty Liver*/drug therapy , Fatty Liver*/immunology , Steroids*/pharmacology , Steroids*/therapeutic use, Animals ; Mice ; Zebrafish ; Neutrophil Infiltration/drug effects ; Male ; Humans ; Disease Models, Animal ; Mice, Inbred C57BL ; Mice, Knockout ; Toll-Like Receptor 4/metabolism ; Liver/pathology ; Liver/drug effects

Elucidation of the biosynthetic pathways of timosaponins reveals the antifungal mechanisms in Anemarrhena asphodeloides.

Autori: Fan B Ji Z Zhu M a ďalší

Zdroj: Journal of advanced research [J Adv Res] 2025 Dec; Vol. 78, pp. 225-237. Date of Electronic Publication: 2025 Jan 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2090-1224 (Electronic) Linking ISSN: 20901224 NLM ISO Abbreviation: J Adv Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Saponins*/pharmacology , Saponins*/biosynthesis , Saponins*/metabolism , Saponins*/chemistry , Steroids*/pharmacology , Steroids*/metabolism , Steroids*/biosynthesis , Steroids*/chemistry , Antifungal Agents*/pharmacology , Antifungal Agents*/metabolism , Biosynthetic Pathways*/genetics , Anemarrhena*/metabolism , Anemarrhena*/genetics , Anemarrhena*/chemistry, Molecular Docking Simulation ; Mutagenesis, Site-Directed ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Intramolecular Transferases

Asterosaponin CN-3 performs an anti-glioma effect by inhibiting the migration and invasion of glioma cells through the regulation of miR-4465/HMGA1/NF-κB signaling pathway.

Autori: Du Y Qiu PC Li TY a ďalší

Zdroj: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 3), pp. 117355. Date of Electronic Publication: 2025 Sep 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Saponins*/pharmacology , Saponins*/therapeutic use , Glioma*/drug therapy , Glioma*/metabolism , Glioma*/pathology , MicroRNAs*/metabolism , MicroRNAs*/genetics , Cell Movement*/drug effects , Cell Movement*/physiology , NF-kappa B*/metabolism , NF-kappa B*/genetics , HMGA1a Protein*/metabolism , HMGA1a Protein*/genetics , Steroids*/pharmacology , Steroids*/therapeutic use , Brain Neoplasms*/metabolism , Brain Neoplasms*/drug therapy , Brain Neoplasms*/pathology, Humans ; Cell Line, Tumor ; Signal Transduction/drug effects ; Signal Transduction/physiology ; Neoplasm Invasiveness ; Animals ; Mice, Nude ; Mice ; Mice, Inbred BALB C ; Gene Expression Regulation, Neoplastic/drug effects

Dose and Duration of Upfront Steroid Administration Have no Prognostic Impact in Dogs With Multicentric Diffuse Large B-Cell Lymphoma.

Autori: Maga I Sabattini S Martini V a ďalší

Zdroj: Veterinary and comparative oncology [Vet Comp Oncol] 2025 Dec; Vol. 23 (4), pp. 509-517. Date of Electronic Publication: 2025 Jul 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Blackwell Country of Publication: England NLM ID: 101185242 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5829 (Electronic) Linking ISSN: 14765810 NLM ISO Abbreviation: Vet Comp Oncol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Dog Diseases*/drug therapy , Dog Diseases*/diagnosis , Lymphoma, Large B-Cell, Diffuse*/veterinary , Lymphoma, Large B-Cell, Diffuse*/drug therapy , Lymphoma, Large B-Cell, Diffuse*/diagnosis , Steroids*/administration & dosage , Steroids*/therapeutic use, Animals ; Dogs ; Retrospective Studies ; Male ; Female ; Prognosis ; Prednisone/administration & dosage ; Prednisone/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Vincristine/therapeutic use ; Cyclophosphamide/therapeutic use ; Flow Cytometry/veterinary ; Doxorubicin/therapeutic use

Molecular insights into steroid resistance in childhood nephrotic syndrome: Gene expression and prognostic miRNA signatures.

Autori: Kochuthakidiyel Suresh P Venkatachalapathy Y C GPD a ďalší

Zdroj: Computational biology and chemistry [Comput Biol Chem] 2025 Dec; Vol. 119, pp. 108584. Date of Electronic Publication: 2025 Jul 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Nephrotic Syndrome*/genetics , Nephrotic Syndrome*/drug therapy , Nephrotic Syndrome*/diagnosis , MicroRNAs*/genetics , Drug Resistance*/genetics , Steroids*/therapeutic use , Steroids*/pharmacology, Humans ; Male ; Female ; Child ; Prognosis ; Receptors, Glucocorticoid/genetics ; Child, Preschool ; Cytochrome P-450 CYP2C8/genetics ; ATP Binding Cassette Transporter, Subfamily B/genetics ; Gene Expression Profiling

LC-MS/MS techniques for the analysis of steroid panel in human cerebrospinal fluid.

Autori: Skodova T Vitku J Bradac O a ďalší

Zdroj: Neurochemistry international [Neurochem Int] 2025 Dec; Vol. 191, pp. 106080. Date of Electronic Publication: 2025 Oct 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tandem Mass Spectrometry*/methods , Steroids*/cerebrospinal fluid, Humans ; Chromatography, Liquid/methods ; Male ; Female ; Middle Aged ; Aged ; Adult ; Liquid Chromatography-Mass Spectrometry

Site-selective arylations of nature-inspired flavonoids or steroidal phenols via C-H or O-H activation.

Autori: Ignácz R Bózsity N Unger D a ďalší

Zdroj: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2530615. Date of Electronic Publication: 2025 Jul 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Phenols*/chemistry , Phenols*/pharmacology , Phenols*/chemical synthesis , Flavonoids*/chemistry , Flavonoids*/pharmacology , Flavonoids*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Steroids*/chemistry , Steroids*/pharmacology , Steroids*/chemical synthesis, Humans ; Structure-Activity Relationship ; Molecular Structure ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Dose-Response Relationship, Drug ; HeLa Cells

Diagnostic Accuracy of Serum Steroids and Peptides in the Evaluation of 46, XY Disorders of Sex Development (DSD).

Autori: Barnabas R Lila AR Memon SS a ďalší

Zdroj: Clinical endocrinology [Clin Endocrinol (Oxf)] 2025 Dec; Vol. 103 (6), pp. 823-832. Date of Electronic Publication: 2025 Aug 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Blackwell Publishing Country of Publication: England NLM ID: 0346653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2265 (Electronic) Linking ISSN: 03000664 NLM ISO Abbreviation: Clin Endocrinol (Oxf) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Disorder of Sex Development, 46,XY*/blood , Disorder of Sex Development, 46,XY*/diagnosis , Steroids*/blood, Humans ; Child ; Male ; Adolescent ; Female ; Child, Preschool ; Prospective Studies ; Sensitivity and Specificity ; Testosterone/blood ; Follicle Stimulating Hormone/blood ; Infant ; Luteinizing Hormone/blood ; Puberty/blood