Suchergebnisse - "senescence"
-
1
Autoren: et al.
Quelle: Inflammopharmacology [Inflammopharmacology] 2025 Nov; Vol. 33 (11), pp. 6555-6575. Date of Electronic Publication: 2025 Oct 11.
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5608 (Electronic) Linking ISSN: 09254692 NLM ISO Abbreviation: Inflammopharmacology Subsets: MEDLINE
MeSH-Schlagworte: Osteoarthritis*/drug therapy , Osteoarthritis*/metabolism , Osteoarthritis*/pathology , Aging*/metabolism , Aging*/pathology , Senescence-Associated Secretory Phenotype*/physiology , Senescence-Associated Secretory Phenotype*/drug effects, Humans ; Chondrocytes/metabolism ; Chondrocytes/drug effects ; Animals ; Senotherapeutics/pharmacology ; Oxidative Stress/physiology ; Oxidative Stress/drug effects ; Cellular Senescence/physiology ; Cellular Senescence/drug effects ; Biomarkers/metabolism
-
2
Autoren: et al.
Quelle: Kidney international [Kidney Int] 2025 Nov; Vol. 108 (5), pp. 811-826. Date of Electronic Publication: 2025 Jun 25.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE
MeSH-Schlagworte: Polycystic Kidney, Autosomal Dominant*/pathology , Polycystic Kidney, Autosomal Dominant*/genetics , Polycystic Kidney, Autosomal Dominant*/drug therapy , Polycystic Kidney, Autosomal Dominant*/enzymology , Cellular Senescence*/drug effects , Cellular Senescence*/genetics , Kidney*/pathology , Kidney*/drug effects , Kidney*/enzymology , Aldehyde Reductase*/metabolism , Aldehyde Reductase*/genetics , Aldehyde Reductase*/antagonists & inhibitors, Animals ; Humans ; Mice ; Disease Models, Animal ; Senescence-Associated Secretory Phenotype/drug effects ; Senescence-Associated Secretory Phenotype/genetics ; Mice, Transgenic ; TRPP Cation Channels/genetics ; TRPP Cation Channels/metabolism ; Dasatinib/pharmacology ; Senotherapeutics/pharmacology ; Disease Progression ; Quercetin/pharmacology ; Male ; Mutation ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Cell Proliferation/drug effects
-
3
Autoren: et al.
Quelle: Ageing research reviews [Ageing Res Rev] 2025 Dec; Vol. 112, pp. 102896. Date of Electronic Publication: 2025 Sep 10.
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 101128963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9649 (Electronic) Linking ISSN: 15681637 NLM ISO Abbreviation: Ageing Res Rev Subsets: MEDLINE
MeSH-Schlagworte: Aging*/pathology , Aging*/drug effects , Chemotherapy-Related Cognitive Impairment*/etiology , Chemotherapy-Related Cognitive Impairment*/pathology , Chemotherapy-Related Cognitive Impairment*/metabolism , Chemotherapy-Related Cognitive Impairment*/physiopathology , Chemotherapy-Related Cognitive Impairment*/psychology , Cellular Senescence*/drug effects , Cellular Senescence*/physiology , Antineoplastic Agents*/adverse effects, Humans ; Animals ; Oxidative Stress/drug effects ; Senescence-Associated Secretory Phenotype/drug effects
-
4
Autoren: et al.
Quelle: Gene [Gene] 2025 Nov 20; Vol. 972, pp. 149774. Date of Electronic Publication: 2025 Sep 22.
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 7706761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0038 (Electronic) Linking ISSN: 03781119 NLM ISO Abbreviation: Gene Subsets: MEDLINE
MeSH-Schlagworte: Prostatic Neoplasms*/therapy , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/drug therapy , Cellular Senescence*/drug effects, Humans ; Male ; Senescence-Associated Secretory Phenotype/drug effects ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/pharmacology ; Senotherapeutics/therapeutic use ; Senotherapeutics/pharmacology
-
5
Autoren: et al.
Quelle: Cells [Cells] 2025 Nov 20; Vol. 14 (22). Date of Electronic Publication: 2025 Nov 20.
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
-
6
Autoren:
Quelle: Frontiers in immunology [Front Immunol] 2025 Nov 11; Vol. 16, pp. 1694567. Date of Electronic Publication: 2025 Nov 11 (Print Publication: 2025).
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
MeSH-Schlagworte: Cellular Senescence*/immunology , Tumor Microenvironment*/immunology , Cancer Pain*/immunology , Cancer Pain*/therapy , Cancer Pain*/etiology , Cancer Pain*/pathology , Cancer Pain*/metabolism , Neoplasms*/immunology , Neoplasms*/complications , Neoplasms*/pathology, Humans ; Animals ; Killer Cells, Natural/immunology ; Senescence-Associated Secretory Phenotype
-
7
Autoren: et al.
Quelle: International journal of chronic obstructive pulmonary disease [Int J Chron Obstruct Pulmon Dis] 2025 Nov 11; Vol. 20, pp. 3631-3645. Date of Electronic Publication: 2025 Nov 11 (Print Publication: 2025).
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101273481 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2005 (Electronic) Linking ISSN: 11769106 NLM ISO Abbreviation: Int J Chron Obstruct Pulmon Dis Subsets: MEDLINE
MeSH-Schlagworte: Forkhead Box Protein O3*/metabolism , Forkhead Box Protein O3*/genetics , Azithromycin*/pharmacology , Pulmonary Disease, Chronic Obstructive*/metabolism , Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/pathology , Pulmonary Disease, Chronic Obstructive*/etiology , Pulmonary Disease, Chronic Obstructive*/physiopathology , Pulmonary Disease, Chronic Obstructive*/prevention & control , Cyclin D1*/metabolism , Cyclin D1*/genetics , Lung*/drug effects , Lung*/pathology , Lung*/metabolism , Lung*/physiopathology , Cellular Senescence*/drug effects , Epithelial Cells*/drug effects , Epithelial Cells*/pathology , Epithelial Cells*/metabolism , Smoke*/adverse effects , Cigarette Smoking*/adverse effects , Pulmonary Emphysema*/pathology , Pulmonary Emphysema*/metabolism , Pulmonary Emphysema*/physiopathology , Pulmonary Emphysema*/prevention & control, Humans ; Animals ; Signal Transduction/drug effects ; Disease Models, Animal ; Male ; Female ; Cell Line ; Middle Aged ; Mice, Inbred C57BL ; Aged ; Senescence-Associated Secretory Phenotype/drug effects ; Tumor Suppressor Protein p53/metabolism ; Cyclin-Dependent Kinase Inhibitor p21/metabolism ; Mice ; Case-Control Studies
-
8
Autoren: et al.
Quelle: ACS nano [ACS Nano] 2025 Nov 11; Vol. 19 (44), pp. 38408-38427. Date of Electronic Publication: 2025 Oct 28.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE
MeSH-Schlagworte: Intervertebral Disc Degeneration*/drug therapy , Intervertebral Disc Degeneration*/pathology , Intervertebral Disc Degeneration*/metabolism , Cellular Senescence*/drug effects , Cellular Microenvironment*/drug effects, Humans ; Animals ; Macrophages/drug effects ; Macrophages/metabolism ; Nucleus Pulposus/drug effects ; Nucleus Pulposus/pathology ; Nucleus Pulposus/metabolism ; Interleukin-1/pharmacology ; Interleukin-1/metabolism ; Nanoparticles/chemistry ; Senescence-Associated Secretory Phenotype/drug effects ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Mice
-
9
Autoren: et al.
Quelle: Experimental gerontology [Exp Gerontol] 2025 Nov; Vol. 211, pp. 112900. Date of Electronic Publication: 2025 Sep 25.
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE
MeSH-Schlagworte: Fibroblasts*/metabolism , Fibroblasts*/pathology , Cellular Senescence*/physiology , Transforming Growth Factor beta*/metabolism , Transforming Growth Factor beta*/physiology , Skin Diseases*/metabolism , Skin Diseases*/pathology , Skin Aging*, Humans ; Signal Transduction ; Senescence-Associated Secretory Phenotype ; Skin/metabolism ; Skin/pathology ; Oxidative Stress ; Animals ; Extracellular Matrix/metabolism ; Reactive Oxygen Species/metabolism
-
10
Autoren: et al.
Quelle: Science China. Life sciences [Sci China Life Sci] 2025 Nov; Vol. 68 (11), pp. 3329-3339. Date of Electronic Publication: 2025 Sep 05.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Science China Press, co-published with Springer Country of Publication: China NLM ID: 101529880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1869-1889 (Electronic) Linking ISSN: 16747305 NLM ISO Abbreviation: Sci China Life Sci Subsets: MEDLINE
MeSH-Schlagworte: Progeria*/metabolism , Progeria*/pathology , Progeria*/genetics , Lysosomes*/metabolism , Lysosomes*/pathology , Cellular Senescence*, Humans ; Lamin Type A/metabolism ; Lamin Type A/genetics ; Autophagy ; DNA Damage ; Protein Kinase C/metabolism ; Senescence-Associated Secretory Phenotype ; Fibroblasts/metabolism ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Protein Precursors/metabolism ; Protein Precursors/genetics
-
11
Autoren:
Quelle: Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2025 Nov 01; Vol. 86 (5), pp. 435-447. Date of Electronic Publication: 2025 Nov 01.
Publikationsart: Journal Article; Systematic Review; Review
Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7902492 Publication Model: Electronic Cited Medium: Internet ISSN: 1533-4023 (Electronic) Linking ISSN: 01602446 NLM ISO Abbreviation: J Cardiovasc Pharmacol Subsets: MEDLINE
MeSH-Schlagworte: Cellular Senescence* , Muscle, Smooth, Vascular*/pathology , Muscle, Smooth, Vascular*/metabolism , Muscle, Smooth, Vascular*/physiopathology , Muscle, Smooth, Vascular*/drug effects , Myocytes, Smooth Muscle*/pathology , Myocytes, Smooth Muscle*/metabolism , Myocytes, Smooth Muscle*/drug effects , Cell Transdifferentiation* , Cardiovascular Diseases*/pathology , Cardiovascular Diseases*/metabolism , Cardiovascular Diseases*/physiopathology , Cell Plasticity*, Humans ; Animals ; Phenotype ; Signal Transduction ; Senescence-Associated Secretory Phenotype ; Vascular Calcification/pathology ; Vascular Calcification/metabolism ; Cell Proliferation
-
12
Autoren:
Quelle: International journal of molecular medicine [Int J Mol Med] 2025 Nov; Vol. 56 (5). Date of Electronic Publication: 2025 Sep 05.
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE
MeSH-Schlagworte: Cellular Senescence* , Liver Diseases*/pathology , Liver Diseases*/metabolism, Humans ; Animals ; Senescence-Associated Secretory Phenotype ; Signal Transduction ; Biomarkers/metabolism
-
13
Autoren: et al.
Quelle: European journal of internal medicine [Eur J Intern Med] 2025 Nov; Vol. 141, pp. 106488. Date of Electronic Publication: 2025 Aug 25.
Publikationsart: Journal Article; Review
Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9003220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0828 (Electronic) Linking ISSN: 09536205 NLM ISO Abbreviation: Eur J Intern Med Subsets: MEDLINE
-
14
Autoren: et al.
Quelle: Scientific reports [Sci Rep] 2025 Oct 21; Vol. 15 (1), pp. 36738. Date of Electronic Publication: 2025 Oct 21.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
MeSH-Schlagworte: Cellular Senescence*/drug effects , Human Umbilical Vein Endothelial Cells*/drug effects , Human Umbilical Vein Endothelial Cells*/metabolism , Oxidative Stress*/drug effects , Antineoplastic Agents*/pharmacology, Humans ; Reactive Oxygen Species/metabolism ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Ataxia Telangiectasia Mutated Proteins/antagonists & inhibitors ; Methotrexate/pharmacology ; Phenotype ; Senescence-Associated Secretory Phenotype/drug effects ; Mitochondria/metabolism ; Mitochondria/drug effects ; Etoposide/pharmacology
-
15
Autoren: et al.
Quelle: Cells [Cells] 2025 Oct 08; Vol. 14 (19). Date of Electronic Publication: 2025 Oct 08.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
MeSH-Schlagworte: tert-Butylhydroperoxide*/pharmacology , Mesenchymal Stem Cells*/drug effects , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Cellular Senescence*/drug effects , Dermis*/cytology , Models, Biological*, Humans ; Cell Proliferation/drug effects ; Hydrogen Peroxide/pharmacology ; Adult ; Reactive Oxygen Species/metabolism ; DNA Damage/drug effects ; Cells, Cultured ; Cell Cycle Checkpoints/drug effects ; Oxidative Stress/drug effects ; Senescence-Associated Secretory Phenotype/drug effects
-
16
Autoren: et al.
Quelle: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Dec; Vol. 149, pp. 157513. Date of Electronic Publication: 2025 Nov 05.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
MeSH-Schlagworte: Pulmonary Disease, Chronic Obstructive*/drug therapy , Pulmonary Disease, Chronic Obstructive*/metabolism , Cellular Senescence*/drug effects , Drugs, Chinese Herbal*/pharmacology , Membrane Proteins*/metabolism , CD4-Positive T-Lymphocytes*/drug effects , Nucleotidyltransferases*/metabolism, Humans ; Signal Transduction/drug effects ; Animals ; Mice ; Male ; Female ; Aged ; Mice, Inbred C57BL ; Middle Aged ; Jurkat Cells ; Molecular Docking Simulation ; Disease Models, Animal ; T-Cell Senescence
-
17
Autoren: et al.
Quelle: Blood [Blood] 2025 Nov 27; Vol. 146 (22), pp. 2656-2669.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
MeSH-Schlagworte: Cellular Senescence*/immunology , Graft vs Host Disease*/immunology , Graft vs Host Disease*/prevention & control , Graft vs Host Disease*/pathology , Immunity, Innate* , T-Lymphocytes*/immunology , T-Lymphocytes*/pathology , Interleukin-9*/immunology , Lymphocytes*/immunology, Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells/immunology ; Hematopoietic Stem Cells/cytology ; T-Cell Senescence
-
18
Autoren: et al.
Quelle: Communications biology [Commun Biol] 2025 Nov 26; Vol. 8 (1), pp. 1696. Date of Electronic Publication: 2025 Nov 26.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
-
19
Autoren: et al.
Quelle: Scientific reports [Sci Rep] 2025 Nov 19; Vol. 15 (1), pp. 40845. Date of Electronic Publication: 2025 Nov 19.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
MeSH-Schlagworte: Diabetes Mellitus, Type 1*/blood , Diabetes Mellitus, Type 1*/pathology , Senescence-Associated Secretory Phenotype*, Humans ; Male ; Female ; Biomarkers/blood ; Cross-Sectional Studies ; Adolescent ; Child ; Young Adult ; Adult ; Insulin-Secreting Cells/metabolism ; Insulin-Secreting Cells/pathology ; Cellular Senescence ; Child, Preschool ; Disease Progression ; Cohort Studies
-
20
Accelerated T-cell senescence and persistent inflammation in older adults with rheumatoid arthritis.
Autoren: et al.
Quelle: International immunopharmacology [Int Immunopharmacol] 2025 Nov 14; Vol. 165, pp. 115518. Date of Electronic Publication: 2025 Sep 08.
Publikationsart: Journal Article
Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
MeSH-Schlagworte: Arthritis, Rheumatoid*/immunology , Cellular Senescence*/immunology , T-Lymphocytes*/immunology , Inflammation*/immunology, Humans ; Aged ; Male ; Female ; Cytokines/blood ; Cytokines/metabolism ; Middle Aged ; Immunosenescence ; Cells, Cultured ; Aged, 80 and over ; T-Cell Senescence
Full Text Finder
Nájsť tento článok vo Web of Science