Suchergebnisse - "risk assessment"

The value of a structured, systematic approach to benefit-risk assessment of medicines: A South African regulator case study.

Autoren: Danks L Semete-Makokotlela B Chuma D et al.

Quelle: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2025 Nov; Vol. 162, pp. 105893. Date of Electronic Publication: 2025 Jun 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Drug and Narcotic Control* , Risk Assessment*/methods, Decision Making ; Prospective Studies ; Retrospective Studies ; South Africa

Five essential features for adoption of clinical risk prediction tools: Insights from the VOCAL-Penn score.

Autoren: Khan K Bolas M Mahmud N

Quelle: Hepatology communications [Hepatol Commun] 2025 Dec 01; Vol. 9 (12). Date of Electronic Publication: 2025 Dec 01 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101695860 Publication Model: eCollection Cited Medium: Internet ISSN: 2471-254X (Electronic) Linking ISSN: 2471254X NLM ISO Abbreviation: Hepatol Commun Subsets: MEDLINE

MeSH-Schlagworte: Risk Assessment*/methods, Humans ; Interviews as Topic ; Qualitative Research

Breaking the "Toxic Ignorance Cycles" that Hinder New Approach Method (NAM) Acceptance in Environmental Risk Assessment.

Autoren: Jeffcoat P Hickey GM Maguire S et al.

Quelle: Environmental science & technology [Environ Sci Technol] 2025 Oct 21; Vol. 59 (41), pp. 21801-21811. Date of Electronic Publication: 2025 Oct 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0213155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5851 (Electronic) Linking ISSN: 0013936X NLM ISO Abbreviation: Environ Sci Technol Subsets: MEDLINE

MeSH-Schlagworte: Risk Assessment*/methods , Ecotoxicology*, Decision Making ; Uncertainty

Epileptogenesis in meningioma: Theories, putative biomarkers, and postoperative risk.

Autoren: Cook WH Gillespie CS Bakhsh A et al.

Quelle: Epilepsia [Epilepsia] 2025 Nov; Vol. 66 (11), pp. 4079-4090. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE

MeSH-Schlagworte: Meningioma*/complications , Meningioma*/surgery , Seizures*/diagnosis , Seizures*/etiology , Seizures*/prevention & control , Postoperative Complications*/diagnosis , Postoperative Complications*/etiology , Postoperative Complications*/prevention & control , Risk Assessment*/methods , Epilepsy*/diagnosis , Epilepsy*/etiology , Epilepsy*/prevention & control, Humans ; Biomarkers/analysis ; Risk Factors ; Brain/physiopathology

High measured GFR as a predictor of all-cause mortality and cardiovascular disease in a prospective non-diabetic population cohort.

Autoren: Eriksen BO Fasiolo M Mathisen UD et al.

Quelle: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2025 Oct 30; Vol. 40 (11), pp. 2091-2103.

Publikationsart: Comparative Study; Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE

MeSH-Schlagworte: Glomerular Filtration Rate* , Cardiovascular Diseases*/diagnosis , Cardiovascular Diseases*/etiology , Cardiovascular Diseases*/mortality , Risk Assessment*/methods , Kidney Function Tests*/methods , Kidney Function Tests*/statistics & numerical data , Mortality*/trends, Predictive Value of Tests ; Norway/epidemiology ; Iohexol/metabolism ; Metabolic Clearance Rate ; Creatinine/urine ; Cystatin C/urine ; Prospective Studies ; Longitudinal Studies ; Humans ; Male ; Female ; Middle Aged ; Follow-Up Studies ; Proportional Hazards Models ; Heart Disease Risk Factors ; Albuminuria/diagnosis ; Albuminuria/mortality ; Albuminuria/urine ; Cause of Death

CTBN-PH: A continuous-time Bayesian network for individualised diagnostic risk prediction.

Autoren: Guillamet GH Seguí FL Alaball JV et al.

Quelle: Computers in biology and medicine [Comput Biol Med] 2025 Oct; Vol. 197 (Pt B), pp. 111069. Date of Electronic Publication: 2025 Sep 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1250250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0534 (Electronic) Linking ISSN: 00104825 NLM ISO Abbreviation: Comput Biol Med Subsets: MEDLINE

MeSH-Schlagworte: Bayes Theorem* , Risk Assessment*/methods, Humans ; Proportional Hazards Models

Significance of Naples prognostic score for postoperative complications after colorectal cancer surgery.

Autoren: Ohkuma M Takano Y Goto K et al.

Quelle: Surgery today [Surg Today] 2025 Oct; Vol. 55 (10), pp. 1481-1487. Date of Electronic Publication: 2025 May 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Country of Publication: Japan NLM ID: 9204360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-2813 (Electronic) Linking ISSN: 09411291 NLM ISO Abbreviation: Surg Today Subsets: MEDLINE

MeSH-Schlagworte: Severity of Illness Index* , Colorectal Neoplasms*/complications , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/surgery , Postoperative Complications*/classification , Postoperative Complications*/epidemiology , Postoperative Complications*/etiology , Colectomy*/adverse effects , Colectomy*/statistics & numerical data , Risk Assessment*/methods , Nutritional Status*, Retrospective Studies ; Prognosis ; Predictive Value of Tests ; Multivariate Analysis ; Age Factors ; Risk Factors ; Blood Loss, Surgical/statistics & numerical data ; Inflammation ; Humans ; Male ; Female ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Operative Time ; Length of Stay

Scalable Bayesian Nonparametric Method for Clinical Risk Prediction Using Large-Scale Data From Heterogeneous Populations.

Autoren: Dong N Nair N Du D

Quelle: IEEE journal of biomedical and health informatics [IEEE J Biomed Health Inform] 2025 Oct; Vol. 29 (10), pp. 7514-7524.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Institute of Electrical and Electronics Engineers Country of Publication: United States NLM ID: 101604520 Publication Model: Print Cited Medium: Internet ISSN: 2168-2208 (Electronic) Linking ISSN: 21682194 NLM ISO Abbreviation: IEEE J Biomed Health Inform Subsets: MEDLINE

MeSH-Schlagworte: Bayes Theorem* , Risk Assessment*/methods , Statistics, Nonparametric*, Humans ; Algorithms ; Computer Simulation ; Databases, Factual ; Heart Failure/mortality ; Models, Statistical

In Silico Frontiers Shaping the Next Generation of Transformation Product Prediction and Toxicological Assessment.

Autoren: Löffler P Schymanski EL Henschel H et al.

Quelle: Environmental science & technology [Environ Sci Technol] 2025 Sep 16; Vol. 59 (36), pp. 19095-19106. Date of Electronic Publication: 2025 Sep 02.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0213155 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5851 (Electronic) Linking ISSN: 0013936X NLM ISO Abbreviation: Environ Sci Technol Subsets: MEDLINE

MeSH-Schlagworte: Computer Simulation* , Risk Assessment* , Environmental Pollutants*/toxicity, Machine Learning ; Quantitative Structure-Activity Relationship

Validation and Refinement of Scores to Predict Stroke Risk: Prospective Cohort Study.

Autoren: Meng H Liu Z Pan D et al.

Quelle: JMIR public health and surveillance [JMIR Public Health Surveill] 2025 Aug 21; Vol. 11, pp. e72497. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101669345 Publication Model: Electronic Cited Medium: Internet ISSN: 2369-2960 (Electronic) Linking ISSN: 23692960 NLM ISO Abbreviation: JMIR Public Health Surveill Subsets: MEDLINE

MeSH-Schlagworte: Stroke*/diagnosis , Stroke*/epidemiology , Stroke*/etiology , Risk Assessment*/methods , Risk Assessment*/standards, China/epidemiology ; Predictive Value of Tests ; Logistic Models ; Prospective Studies ; Follow-Up Studies ; Humans ; Male ; Female ; Adult ; Middle Aged ; ROC Curve ; Area Under Curve ; Risk Factors ; Hospitalization/statistics & numerical data

Natural History of Cerebral Aneurysms: Risk Factors for Rupture and Implications for Management.

Autoren: Gibson DP Kulwin CG Shah KJ et al.

Quelle: Neuroimaging clinics of North America [Neuroimaging Clin N Am] 2025 Aug; Vol. 35 (3), pp. 303-310.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: W.B. Saunders Co Country of Publication: United States NLM ID: 9211377 Publication Model: Print Cited Medium: Internet ISSN: 1557-9867 (Electronic) Linking ISSN: 10525149 NLM ISO Abbreviation: Neuroimaging Clin N Am Subsets: MEDLINE

MeSH-Schlagworte: Intracranial Aneurysm*/diagnostic imaging , Intracranial Aneurysm*/epidemiology , Intracranial Aneurysm*/therapy , Aneurysm, Ruptured*/diagnostic imaging , Aneurysm, Ruptured*/epidemiology , Aneurysm, Ruptured*/etiology , Risk Assessment*/methods , Neuroimaging*/methods, Humans ; Risk Factors ; Rupture, Spontaneous/diagnostic imaging ; Rupture, Spontaneous/epidemiology ; Rupture, Spontaneous/etiology ; Artificial Intelligence ; Disease Management

[Development and validation of a risk prediction model for severe acute pancreatitis induced by hypertriglyceridemia].

Autoren: Wang Z Deng HZ Peng KX et al.

Körperschaften: Wang Z Deng HZ Peng KX et al.

Quelle: Zhonghua wai ke za zhi [Chinese journal of surgery] [Zhonghua Wai Ke Za Zhi] 2025 Aug 01; Vol. 63 (8), pp. 720-726.

Publikationsart: Comparative Study; English Abstract; Journal Article; Multicenter Study; Validation Study; English Abstract

Info zur Zeitschrift: Publisher: Zhonghua yi xue hui, Wai ke xue hui Country of Publication: China NLM ID: 0153611 Publication Model: Print Cited Medium: Print ISSN: 0529-5815 (Print) Linking ISSN: 05295815 NLM ISO Abbreviation: Zhonghua Wai Ke Za Zhi Subsets: MEDLINE

MeSH-Schlagworte: Hypertriglyceridemia*/blood , Hypertriglyceridemia*/complications , Hypertriglyceridemia*/pathology , Pancreatitis*/diagnosis , Pancreatitis*/etiology , Risk Assessment*/methods , Risk Assessment*/standards , Predictive Learning Models*, Retrospective Studies ; Humans ; Male ; Female ; Child ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Risk Factors ; Triglycerides/blood ; Odds Ratio ; Blood Glucose/analysis ; Body Mass Index ; Blood Cell Count ; Nomograms ; Area Under Curve ; Multiple Organ Failure/diagnosis ; Multiple Organ Failure/etiology ; Predictive Value of Tests ; Logistic Models

Prioritisation of co-formulants and plant protection products for non-dietary risk assessment using NAMs.

Autoren: Stagkos-Georgiadis A Baffour-Duah B Tralau T et al.

Quelle: Archives of toxicology [Arch Toxicol] 2025 Aug; Vol. 99 (8), pp. 3205-3221. Date of Electronic Publication: 2025 Jul 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE

MeSH-Schlagworte: Risk Assessment*/methods , Plant Preparations*/chemistry, Humans ; Computer Simulation ; Toxicity Tests/methods

Evaluating the Exposome Score for Schizophrenia in a Transdiagnostic Psychosis Cohort: Associations With Psychosis Risk, Symptom Severity, and Personality Traits.

Autoren: Kromenacker B Yassin W Keshavan M et al.

Quelle: Schizophrenia bulletin [Schizophr Bull] 2025 Sep 08; Vol. 51 (5), pp. 1454-1463.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0236760 Publication Model: Print Cited Medium: Internet ISSN: 1745-1701 (Electronic) Linking ISSN: 05867614 NLM ISO Abbreviation: Schizophr Bull Subsets: MEDLINE

MeSH-Schlagworte: Psychotic Disorders*/classification , Psychotic Disorders*/diagnosis , Psychotic Disorders*/etiology , Schizophrenia*/classification , Schizophrenia*/diagnosis , Schizophrenia*/etiology , Exposome* , Severity of Illness Index* , Risk Assessment*/methods, Case-Control Studies ; Cross-Sectional Studies ; Phenotype ; Regression Analysis ; Models, Psychological ; Reproducibility of Results ; Odds Ratio ; Risk Factors ; Symptom Burden ; Clinical Relevance ; Humans ; Male ; Female ; Adult ; Middle Aged ; Personality Inventory

Clinical and Biofluid Biomarkers of Sleep Dysfunction in Parkinson's Disease.

Autoren: Gómez-Ocádiz R Svenningsson P

Quelle: Sleep medicine clinics [Sleep Med Clin] 2025 Sep; Vol. 20 (3), pp. 259-268. Date of Electronic Publication: 2025 Jun 09.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 101271531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-4088 (Electronic) Linking ISSN: 1556407X NLM ISO Abbreviation: Sleep Med Clin Subsets: MEDLINE

MeSH-Schlagworte: Parkinson Disease*/complications , Parkinson Disease*/diagnosis , Parkinson Disease*/physiopathology , Sleep Wake Disorders*/diagnosis , Sleep Wake Disorders*/etiology , Sleep Wake Disorders*/physiopathology , Risk Assessment*/methods, Humans ; Sleep/physiology ; Biomarkers/analysis ; Prodromal Symptoms ; Synucleinopathies/diagnosis ; Synucleinopathies/etiology ; Synucleinopathies/physiopathology ; Early Diagnosis ; REM Sleep Behavior Disorder/diagnosis ; REM Sleep Behavior Disorder/etiology ; REM Sleep Behavior Disorder/physiopathology

SHAP analysis and comparative performance of the HEART, HET, and SVEAT scores in 30-day MACE prediction.

Autoren: Sarıdaş A Aydin ÖF

Quelle: The American journal of emergency medicine [Am J Emerg Med] 2025 Sep; Vol. 95, pp. 1-6. Date of Electronic Publication: 2025 May 06.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: W B Saunders Country of Publication: United States NLM ID: 8309942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8171 (Electronic) Linking ISSN: 07356757 NLM ISO Abbreviation: Am J Emerg Med Subsets: MEDLINE

MeSH-Schlagworte: Cardiovascular Diseases*/complications , Cardiovascular Diseases*/diagnosis , Cardiovascular Diseases*/epidemiology , Risk Assessment*/methods , Chest Pain*/diagnosis , Chest Pain*/etiology , Emergency Service, Hospital*, Predictive Value of Tests ; ROC Curve ; Risk Factors ; Retrospective Studies ; Acute Disease ; Humans ; Male ; Female ; Middle Aged ; Aged

Sex-specific thresholds of peak oxygen consumption for detecting cardiometabolic risk in children and adolescents with type 1 diabetes.

Autoren: García-Hermoso A Huerta-Uribe N Hormazábal-Aguayo I et al.

Quelle: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2025 Sep; Vol. 227, pp. 112410. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE

MeSH-Schlagworte: Sex Factors* , Risk Assessment*/methods , Diabetes Mellitus, Type 1*/blood , Diabetes Mellitus, Type 1*/complications , Diabetes Mellitus, Type 1*/pathology , Metabolic Syndrome*/diagnosis , Metabolic Syndrome*/epidemiology , Metabolic Syndrome*/etiology , Oxygen Consumption*/physiology, Longitudinal Studies ; Spain/epidemiology ; Logistic Models ; Predictive Value of Tests ; Humans ; Male ; Female ; Child ; Reference Values ; Cardiometabolic Risk Factors ; Adolescent ; Follow-Up Studies ; ROC Curve ; Exercise Test ; Waist Circumference ; Lipids/blood ; Glycated Hemoglobin/analysis ; Blood Pressure ; Biomarkers/analysis ; Brazil/epidemiology

Predicted pro-inflammatory high-sensitivity C-reactive protein score and inflammatory bowel disease: a cross-sectional study.

Autoren: Kim DH Okekunle AP Kang J et al.

Quelle: The Korean journal of internal medicine [Korean J Intern Med] 2025 Sep; Vol. 40 (5), pp. 734-746. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Korean Association of Internal Medicine Country of Publication: Korea (South) NLM ID: 8712418 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2005-6648 (Electronic) Linking ISSN: 12263303 NLM ISO Abbreviation: Korean J Intern Med Subsets: MEDLINE

MeSH-Schlagworte: Inflammatory Bowel Diseases*/blood , Inflammatory Bowel Diseases*/diagnosis , Inflammatory Bowel Diseases*/epidemiology , C-Reactive Protein*/analysis , Inflammation Mediators*/blood , Risk Assessment*/methods, Odds Ratio ; Cross-Sectional Studies ; Case-Control Studies ; Republic of Korea/epidemiology ; Prevalence ; Humans ; Male ; Female ; Adult ; Middle Aged ; Predictive Value of Tests ; Endoscopy, Gastrointestinal ; Biomarkers/blood ; Logistic Models ; Area Under Curve ; Multivariate Analysis ; Risk Factors

A Bayesian network-based predictive model for postoperative delirium following coronary artery bypass grafting.

Autoren: Xu L Zhang Y Zhang J et al.

Quelle: BMC psychiatry [BMC Psychiatry] 2025 Aug 26; Vol. 25 (1), pp. 822. Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100968559 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-244X (Electronic) Linking ISSN: 1471244X NLM ISO Abbreviation: BMC Psychiatry Subsets: MEDLINE

MeSH-Schlagworte: Coronary Artery Bypass*/adverse effects , Emergence Delirium*/diagnosis , Emergence Delirium*/epidemiology , Emergence Delirium*/etiology , Predictive Learning Models* , Risk Assessment*/methods, Bayes Theorem ; Humans ; Male ; Female ; Middle Aged ; Aged ; Datasets as Topic ; Area Under Curve ; Logistic Models ; Incidence ; Organ Dysfunction Scores ; Predictive Value of Tests

A hybrid approach for forecasting peak expiratory flow rate in asthma patients using combined linear regression and random forest model.

Autoren: Alkobaisi S Bae WD Safdar MF et al.

Quelle: PloS one [PLoS One] 2025 Aug 21; Vol. 20 (8), pp. e0326036. Date of Electronic Publication: 2025 Aug 21 (Print Publication: 2025).

Publikationsart: Journal Article; Validation Study

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Peak Expiratory Flow Rate*/physiology , Asthma*/diagnosis , Asthma*/physiopathology , Machine Learning* , Risk Assessment*/methods, Severity of Illness Index ; Random Forest ; Linear Models ; Humans ; Disease Progression ; Datasets as Topic ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Male ; Female