Suchergebnisse - "rho GTP-Binding Proteins/metabolism"

The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning

Autoren: Michael C Armstrong Yannic R Weiß Lila E Hoachlander-Hobby et al.

Quelle: EMBO J
Armstrong, M C, Weiß, Y R, Hoachlander-Hobby, L E, Roy, A A, Visco, I, Moe, A, Golding, A E, Hansen, S D, Bement, W M & Bieling, P 2025, ' The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning ', The EMBO journal, vol. 44, no. 9, 71, pp. 2620-2657 . https://doi.org/10.1038/s44318-025-00418-z

Schlagwörter: Guanine Nucleotide Exchange Factors/metabolism, rho GTP-Binding Proteins, Cell Membrane/metabolism, Cell Membrane, GTPase-Activating Proteins, GTPase-Activating Proteins/metabolism, Guanine Nucleotide Dissociation Inhibitors/metabolism, Article, Enzyme Activation, rho GTP-Binding Proteins/metabolism, Guanine Nucleotide Exchange Factors, Humans, Animals, Protein Binding, Guanine Nucleotide Dissociation Inhibitors

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40164947
https://kclpure.kcl.ac.uk/ws/files/344447849/armstrong-et-al-the-biochemical-mechanism-of-rho-gtpase-membrane-binding-activation-and-retention-in-activity-patterning.pdf

Clostridium botulinum C3bot mediated effects on cytokine-induced psoriasis-like phenotype in full-thickness skin model

Autoren: Astrid Rohrbeck Vanessa Anna Bruhn Nali Hussein et al.

Quelle: Naunyn Schmiedebergs Arch Pharmacol

Schlagwörter: ADP Ribose Transferases, rho GTP-Binding Proteins, Botulinum Toxins, Phenotype, Interleukin-6, Research, Clostridium botulinum, Humans, Psoriasis, Psoriasis-like phenotype, Humans [MeSH], Clostridium botulinum/metabolism [MeSH], Psoriasis/drug therapy [MeSH], ADP Ribose Transferases [MeSH], ADP-ribosyltransferase, Full-thickness skin model, Clostridium botulinum/genetics [MeSH], C3 exoenzyme, Botulinum Toxins/pharmacology [MeSH], Phenotype [MeSH], rho GTP-Binding Proteins/metabolism [MeSH], Interleukin-6/metabolism [MeSH], Claudin-1, IL-6

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37707681
https://repository.publisso.de/resource/frl:6521737

A computational analysis of the role of integrins and Rho-GTPases in the emergence and disruption of apical-basal polarization in renal epithelial cells

Autoren: Hagelaars, Maria J. Nikolic, Milica Vermeulen, Maud et al.

Quelle: Hagelaars, M J, Nikolic, M, Vermeulen, M, Dekker, S, Bouten, C V C & Loerakker, S 2024, 'A computational analysis of the role of integrins and Rho-GTPases in the emergence and disruption of apical-basal polarization in renal epithelial cells', PLoS Computational Biology, vol. 20, no. 5 May, e1012140. https://doi.org/10.1371/journal.pcbi.1012140

Schlagwörter: Animals, Cell Polarity/physiology, Computational Biology, Computer Simulation, Epithelial Cells/metabolism, Epithelial-Mesenchymal Transition/physiology, Humans, Integrins/metabolism, Kidney/metabolism, Models, Biological, rho GTP-Binding Proteins/metabolism

Dateibeschreibung: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/38768266; info:eu-repo/semantics/altIdentifier/pissn/1553-734X; info:eu-repo/semantics/altIdentifier/eissn/1553-7358

Verfügbarkeit: https://research.tue.nl/en/publications/c14fb454-5d66-40c4-855e-0ba21a144998
https://doi.org/10.1371/journal.pcbi.1012140
https://pure.tue.nl/ws/files/330908579/journal.pcbi.1012140.pdf
https://www.scopus.com/pages/publications/85193570107

Differential Smad2/3 linker phosphorylation is a crosstalk mechanism of Rho/ROCK and canonical TGF-β3 signaling in tenogenic differentiation

Autoren: Melzer, Michaela (University of Giessen) Burk-Luibl, Janina (University of Veterinary Medicine Vienna) Scheiner-Bobis, Georgios (University of Giessen) et al.

Quelle: Scientific Reports 14(1) (2024)

Schlagwörter: RHO-Associated Kinases Metabolism, Phosphorylation, Cell Differentiation Drug Effects, Smad2 Protein Metabolism, Smad3 Protein Metabolism, Signal Transduction, Humans, Mesenchymal Stem Cells Metabolism Cytology Drug Effects, Transforming Growth Factor Beta3 Metabolism, Cells, Cultured, Pyridines Pharmacology, Amides Pharmacology, RHO GTP-Binding Proteins Metabolism

Dateibeschreibung: application/pdf

Relation: isPartOf:https://phaidra.vetmeduni.ac.at/o:605[Open Access Publications]; https://phaidra.vetmeduni.ac.at/o:3324

Verfügbarkeit: https://doi.org/10.1038/s41598-024-60717-z
https://phaidra.vetmeduni.ac.at/o:3324

The Role of Rho GTPases in VEGF Signaling in Cancer Cells

Autoren: El Baba, Nada Farran, Mohammad Khalil, Elie Abi et al.

Quelle: Anal Cell Pathol (Amst)
Analytical Cellular Pathology, Vol 2020 (2020)

Schlagwörter: Vascular Endothelial Growth Factor A, rho GTP-Binding Proteins, 0301 basic medicine, Carcinogenesis/metabolism, Cancer Research, Carcinogenesis, Neovascularization, Pathologic/pathology, Review Article, Biochimie, biophysique & biologie moléculaire, Neoplasms/pathology, Pathology and Forensic Medicine, 03 medical and health sciences, rho GTP-Binding Proteins/metabolism, Neoplasms, Animals, Humans, RC254-282, QH573-671, Neovascularization, Pathologic, Signal Transduction/physiology, Vascular Endothelial Growth Factor A/metabolism, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell Biology, General Medicine, Life sciences, 3. Good health, Neovascularization, Pathologic/metabolism, Sciences du vivant, Molecular Medicine, Carcinogenesis/pathology, Cytology, Neoplasms/metabolism, Biochemistry, biophysics & molecular biology, Signal Transduction

Zugangs-URL: http://downloads.hindawi.com/journals/acp/2020/2097214.pdf
https://pubmed.ncbi.nlm.nih.gov/32377503
https://doaj.org/article/a2457c03d5f94bfba1e2e88b9cfd517e
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182966
https://downloads.hindawi.com/journals/acp/2020/2097214.pdf
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182966
https://www.hindawi.com/journals/acp/2020/2097214/
https://laur.lau.edu.lb:8443/xmlui/handle/10725/11876
http://downloads.hindawi.com/journals/acp/2020/2097214.pdf

Nonionotropic Action of Endothelial NMDA Receptors on Blood–Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin

Autoren: Mehra, Anupriya Guérit, Sylvaine Macrez, Richard et al.

Weitere Verfasser: Mehra, Anupriya Guérit, Sylvaine Macrez, Richard et al.

Quelle: Mehra, A, Guérit, S, Macrez, R, Gosselet, F, Sevin, E, Lebas, H, Maubert, E, De Vries, H E, Bardou, I, Vivien, D & Docagne, F 2020, 'Nonionotropic Action of Endothelial NMDA Receptors on Blood-Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin', Journal of Neuroscience, vol. 40, no. 8, pp. 1778-1787. https://doi.org/10.1523/JNEUROSCI.0969-19.2019

Schlagwörter: Male, rho GTP-Binding Proteins, 0301 basic medicine, Cerebral Cortex/drug effects, N-Methylaspartate, [SDV]Life Sciences [q-bio], N-Methyl-D-Aspartate/agonists, Myosins, blood–brain barrier, Receptors, N-Methyl-D-Aspartate, Permeability, neuroinflammation, Cell Line, Mice, 03 medical and health sciences, rho GTP-Binding Proteins/metabolism, Signal Transduction/drug effects, Receptors, Excitatory Amino Acid Agonists, Animals, N-Methylaspartate/pharmacology, Phosphorylation, Endothelial Cells/drug effects, Cerebral Cortex, Neurons, rho-Associated Kinases, 0303 health sciences, Tumor Necrosis Factor-alpha, Phosphorylation/drug effects, Endothelial Cells, Excitatory Amino Acid Agonists/pharmacology, Neurons/drug effects, endothelial cells, [SDV] Life Sciences [q-bio], NMDA, Myosins/metabolism, Tumor Necrosis Factor-alpha/pharmacology, Blood-Brain Barrier, Tissue Plasminogen Activator, rho-Associated Kinases/metabolism, permeability, Tissue Plasminogen Activator/pharmacology, Blood-Brain Barrier/drug effects, signal transduction, Signal Transduction

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.jneurosci.org/content/jneuro/40/8/1778.full.pdf
https://pubmed.ncbi.nlm.nih.gov/31953371
https://www.jneurosci.org/content/jneuro/40/8/1778.full.pdf
https://www.jneurosci.org/content/early/2020/01/15/JNEUROSCI.0969-19.2019
https://research.vumc.nl/en/publications/nonionotropic-action-of-endothelial-nmda-receptors-on-blood-brain
https://pubmed.ncbi.nlm.nih.gov/31953371/
https://www.ncbi.nlm.nih.gov/pubmed/31953371
https://www.jneurosci.org/content/40/8/1778
https://research.vumc.nl/en/publications/a4a26411-b4b2-4bc7-9be7-ff9cfeca3476
https://pure.amsterdamumc.nl/en/publications/a75652f0-b3bd-4441-8a45-b68cc5036bf6
https://doi.org/10.1523/JNEUROSCI.0969-19.2019

CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis.

Autoren: Jantsch-Plunger, V. Gönczy, P. Romano, A. et al.

Schlagwörter: Animals, Caenorhabditis elegans/cytology, Caenorhabditis elegans/genetics, Caenorhabditis elegans Proteins, Cell Division/physiology, Child, Cloning, Molecular, Embryo, Nonmammalian, Female, GTPase-Activating Proteins/genetics, GTPase-Activating Proteins/metabolism, Gene Expression Regulation, Developmental/physiology, Helminth Proteins/genetics, Helminth Proteins/metabolism, Humans, Kinesin/genetics, Kinesin/metabolism, Male, Mitotic Spindle Apparatus/physiology, Models, Biological, Mutation/physiology, Protein Structure, Tertiary/genetics, Subcellular Fractions/metabolism, rho GTP-Binding Proteins/genetics, rho GTP-Binding Proteins/metabolism

Dateibeschreibung: application/pdf

Relation: Journal of Cell Biology; https://iris.unil.ch/handle/iris/50851; serval:BIB_17100; 000087946600006

Verfügbarkeit: https://iris.unil.ch/handle/iris/50851
https://doi.org/10.1083/jcb.149.7.1391

The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration.

Autoren: Tan, N.S. Icre, G. Montagner, A. et al.

Schlagwörter: 1-Phosphatidylinositol 3-Kinase/metabolism, Actins/metabolism, Animals, Cell Movement/physiology, Cell Polarity, Cells, Cultured, Chemotaxis/physiology, Enzyme Activation, Epidermal Growth Factor/metabolism, Humans, Keratinocytes/cytology, Keratinocytes/physiology, Mice, Knockout, PPAR delta/genetics, PPAR delta/metabolism, PPAR-beta/genetics, PPAR-beta/metabolism, Phenotype, Proto-Oncogene Proteins c-akt/genetics, Proto-Oncogene Proteins c-akt/metabolism, Signal Transduction/physiology, Stress Fibers/metabolism, Wound Healing, cdc42 GTP-Binding Protein/metabolism, rac1 GTP-Binding Protein/metabolism, rho GTP-Binding Proteins/metabolism

Relation: Molecular and Cellular Biology; 0270-7306[print], 0270-7306[linking]; https://iris.unil.ch/handle/iris/220751; serval:BIB_A57EC9DCD756; 000250099800015

Verfügbarkeit: https://iris.unil.ch/handle/iris/220751
https://doi.org/10.1128/MCB.00436-07

Coupling of D2R Short but not D2R Long receptor isoform to the Rho/ROCK signaling pathway renders striatal neurons vulnerable to mutant huntingtin.

Autoren: Galan-Rodriguez, B. Martin, E. Brouillet, E. et al.

Schlagwörter: Corpus Striatum/metabolism, Dopamine/metabolism, Humans, Huntingtin Protein/metabolism, Huntington Disease/genetics, Huntington Disease/metabolism, Neostriatum/metabolism, Neurons/metabolism, Protein Isoforms/metabolism, Receptors, Dopamine D2/metabolism, Signal Transduction, rho GTP-Binding Proteins/metabolism, rho-Associated Kinases/metabolism, D2 receptor isoforms, Huntington's disease, aggregates, intracellular signaling, striatal death

Dateibeschreibung: application/pdf

Relation: European Journal of Neuroscience; https://iris.unil.ch/handle/iris/196346; serval:BIB_94F3BC76E274; 000392487100019

Verfügbarkeit: https://iris.unil.ch/handle/iris/196346
https://doi.org/10.1111/ejn.13415

Re-expression of proteins involved in cytokinesis during cardiac hypertrophy

Autoren: Ahuja, P. Perriard, E. Pedrazzini, T. et al.

Schlagwörter: Actomyosin/metabolism Amides/pharmacology Angiotensin II/metabolism Animals Antihypertensive Agents/pharmacology Biological Markers/analysis Calpain/metabolism Cardiomegaly/chemically induced/*metabolism *Cell Nucleus Division Cullin Proteins/metabolism *Cytokinesis Heart/*embryology/growth & development Hypertension/pathology Intracellular Signaling Peptides and Proteins/metabolism Mice Myocytes, Cardiac/metabolism/*physiology Myofibrils/metabolism Protein-Serine-Threonine Kinases/metabolism Pyridines/pharmacology Rats Rats, Inbred Dahl Up-Regulation rho GTP-Binding Proteins/metabolism

Relation: Experimental Cell Research; https://iris.unil.ch/handle/iris/124074; serval:BIB_5B8F33ED8590; 000245412300018

Verfügbarkeit: https://iris.unil.ch/handle/iris/124074
https://doi.org/10.1016/j.yexcr.2007.01.009

CDC42 regulates PYRIN inflammasome assembly.

Autoren: Spel, L. Zaffalon, L. Hou, C. et al.

Quelle: Cell reports, vol. 41, no. 7, pp. 111636

Schlagwörter: Pyrin/metabolism, Inflammasomes/metabolism, Immunity, Innate, rho GTP-Binding Proteins/metabolism, Phosphorylation, CDC42, CP: Immunology, FMF, MEFV, NOCARH, PAAND, PYRIN, RhoA, inflammasome, small GTPase

Dateibeschreibung: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/36384121; info:eu-repo/semantics/altIdentifier/eissn/2211-1247; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_8264D9307A8A1; https://serval.unil.ch/notice/serval:BIB_8264D9307A8A; https://serval.unil.ch/resource/serval:BIB_8264D9307A8A.P001/REF.pdf

Verfügbarkeit: https://serval.unil.ch/notice/serval:BIB_8264D9307A8A
https://doi.org/10.1016/j.celrep.2022.111636
https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01507-8
https://serval.unil.ch/resource/serval:BIB_8264D9307A8A.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_8264D9307A8A1

αE‐catenin is a candidate tumor suppressor for the development of E‐cadherin‐expressing lobular‐type breast cancer

Autoren: De Groot, Jolien S Ratze, Max Ak Van Amersfoort, Miranda et al.

Weitere Verfasser: De Groot, Jolien S Ratze, Max Ak Van Amersfoort, Miranda et al.

Quelle: J Pathol
The Journal of Pathology

Schlagwörter: rho GTP-Binding Proteins, 0301 basic medicine, lobular breast cancer, α-catenin (CTNNA1), alpha-catenin (CTNNA1), rho GTP-Binding Proteins/metabolism, Mice, Knockout, 2. Zero hunger, rho-Associated Kinases, Research Support, Non-U.S. Gov't, Antigens, CD/genetics, Actomyosin, Adherens Junctions, Cadherins, Original Papers, 3. Good health, Gene Expression Regulation, Neoplastic, Phenotype, Adherens Junctions/genetics, rho-Associated Kinases/metabolism, MCF-7 Cells, Female, Signal Transduction, Tumor Suppressor Protein p53/deficiency, Rho/Rock, mouse model, Actomyosin/metabolism, Breast Neoplasms, Breast Neoplasms/genetics, alpha Catenin/genetics, Tumor Suppressor Proteins/genetics, Pathology and Forensic Medicine, 03 medical and health sciences, Antigens, CD, Journal Article, Cell Adhesion, Animals, Humans, Genetic Predisposition to Disease, Neoplasm Invasiveness, Cell Shape, Cell Proliferation, Cadherins/genetics, Tumor Suppressor Proteins, Carcinoma, Lobular/genetics, E-cadherin, Anoikis, Carcinoma, Lobular, Mutation, Tumor Suppressor Protein p53, alpha Catenin

Dateibeschreibung: image/pdf; application/pdf

Zugangs-URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/path.5099
https://pubmed.ncbi.nlm.nih.gov/29774524
http://europepmc.org/articles/PMC6055824
https://onlinelibrary.wiley.com/doi/full/10.1002/path.5099
https://pubmed.ncbi.nlm.nih.gov/29774524/
https://dspace.library.uu.nl/bitstream/1874/371349/1/Groot_et_al_2018_The_Journal_of_Pathology.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055824/
https://www.narcis.nl/publication/RecordID/oai%3Adspace.library.uu.nl%3A1874%2F371349
https://dspace.library.uu.nl/handle/1874/371349
https://www.repository.cam.ac.uk/handle/1810/280079
https://doi.org/10.1002/path.5099
https://doi.org/10.17863/cam.27443

Transthyretin interacts with actin regulators in a Drosophila model of familial amyloid polyneuropathy

Autoren: Silva, MIO Lopes, CS Liz, MA et al.

Weitere Verfasser: Silva, MIO Lopes, CS Liz, MA et al.

Schlagwörter: Actin Cytoskeleton / metabolism, Amyloid Neuropathies, Familial / genetics, Familial / metabolism, Animals, Genetically Modified, Disease Models, Animal, Drosophila, Mutation, Prealbumin / genetics, Prealbumin / metabolism, Retina / metabolism, Signal Transduction, rho GTP-Binding Proteins / metabolism

Dateibeschreibung: application/pdf

Relation: info:eu-repo/grantAgreement/FCT/POR_NORTE/SFRH%2FBD%2F118728%2F2016/PT; info:eu-repo/grantAgreement/FCT/DL 57%2F2016/DL 57%2F2016%2FCP1355%2FCT0022/PT; Scientific Reports, vol.10(1):13596; https://www.nature.com/articles/s41598-020-70377-4; https://hdl.handle.net/10216/143492

Verfügbarkeit: https://hdl.handle.net/10216/143492
https://doi.org/10.1038/s41598-020-70377-4

Zds1/Zds2–PP2ACdc55 complex specifies signaling output from Rho1 GTPase

Autoren: Riko Hatakeyama Valentina Rossio Satoshi Yoshida et al.

Quelle: J Cell Biol

Schlagwörter: rho GTP-Binding Proteins, 0301 basic medicine, Protein Phosphatase 2/metabolism, 0303 health sciences, Saccharomyces cerevisiae Proteins, Signal Transducing/metabolism, Cell Cycle Proteins/metabolism, Supplementary Data, Adaptor Proteins, Cell Cycle Proteins, Saccharomyces cerevisiae, R Medicine, Saccharomyces cerevisiae Proteins/metabolism, 03 medical and health sciences, rho GTP-Binding Proteins/metabolism, Protein Phosphatase 2, Saccharomyces cerevisiae/enzymology, Research Articles, Adaptor Proteins, Signal Transducing, Signal Transduction

Dateibeschreibung: application/pdf

Zugangs-URL: https://rupress.org/jcb/article-pdf/212/1/51/1370462/jcb_201508119.pdf
https://pubmed.ncbi.nlm.nih.gov/26728856
https://europepmc.org/article/MED/26728856
https://aura.abdn.ac.uk/handle/2164/15766
https://pubmed.ncbi.nlm.nih.gov/26728856/
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201902211664890097
http://www.ncbi.nlm.nih.gov/pubmed/26728856
http://jcb.rupress.org/content/212/1/51

Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease

Autoren: Christian Faul Alla Mitrofanova Mayrin Correa-Medina et al.

Weitere Verfasser: Christian Faul Alla Mitrofanova Mayrin Correa-Medina et al.

Quelle: Journal of the American Society of Nephrology. 26:133-147

Schlagwörter: Cyclic Nucleotide Phosphodiesterases, 0301 basic medicine, Integrins, podocyte, Kidney Glomerulus, glomerular disease, Apoptosis, Mice, Transgenic, Integrins/metabolism, Kidney Glomerulus/injuries, Integrin alphaVbeta3/metabolism, Transgenic, Gene Expression Regulation, Enzymologic, Receptors, Urokinase Plasminogen Activator, Urokinase Plasminogen Activator/blood, Mice, 03 medical and health sciences, rho GTP-Binding Proteins/metabolism, Cell Movement, Receptors, Animals, Humans, Podocytes/pathology, Type 3/metabolism, 10. No inequality, Inbred BALB C, Oligonucleotide Array Sequence Analysis, Mice, Inbred BALB C, 0303 health sciences, Enzymologic, Podocytes/cytology, Podocytes, diabetic nephropathy, Neuropeptides, Kidney Diseases/metabolism, rac1 GTP-Binding Protein/metabolism, Integrin alphaVbeta3, Neuropeptides/metabolism, Cyclic Nucleotide Phosphodiesterases, Type 3, Kidney Glomerulus/pathology, Sphingomyelin Phosphodiesterase/metabolism, FSGS, HEK293 Cells, Phenotype, Gene Expression Regulation, Female, Kidney Diseases, proteinuria

Dateibeschreibung: 133~147

Zugangs-URL: https://jasn.asnjournals.org/content/jnephrol/26/1/133.full.pdf
https://pubmed.ncbi.nlm.nih.gov/24925721
https://europepmc.org/articles/PMC4279736
https://yonsei.pure.elsevier.com/en/publications/sphingomyelinase-like-phosphodiesterase-3b-expression-levels-dete
https://www.ncbi.nlm.nih.gov/pubmed/24925721
https://jasn.asnjournals.org/lookup/doi/10.1681/ASN.2013111213
https://pubmed.ncbi.nlm.nih.gov/24925721/
https://miami.pure.elsevier.com/en/publications/sphingomyelinase-like-phosphodiesterase-3b-expression-levels-dete

Cellular mechanisms of bacterial internalization counteracted by Yersinia

Autoren: Fällman, Maria Gustavsson, Anna

Quelle: International Review of Cytology International Review of Cell and Molecular Biology. :135-188

Schlagwörter: Bacterial Adhesion, Bacterial Outer Membrane Proteins/genetics/*metabolism, Bacterial Toxins/metabolism, Endocytosis/*physiology, Humans, Phagocytosis/physiology, Receptors, Fc/metabolism, Virulence Factors/administration & dosage/metabolism, Yersinia/*metabolism/pathogenicity, Yersinia Infections, rho GTP-Binding Proteins/metabolism, MEDICINE, MEDICIN

Dateibeschreibung: print

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-32251

Phosphatase of Regenerating Liver 3 (PRL3) Provokes a Tyrosine Phosphoproteome to Drive Prometastatic Signal Transduction

Autoren: Walls, Chad D. Iliuk, Anton Bai, Yunpeng et al.

Weitere Verfasser: Walls, Chad D. Iliuk, Anton Bai, Yunpeng et al.

Quelle: Molecular & Cellular Proteomics. 12:3759-3777

Schlagwörter: 0301 basic medicine, Integrins, Cell Transformation, Phosphatidylinositol 3-Kinases, Epithelial-Mesenchymal Transition -- Genetics, src-Family Kinases -- Metabolism, Cell Movement, Receptors, Phosphotyrosine -- Metabolism, rho GTP-Binding Proteins -- Genetics, Receptors, Platelet-Derived Growth Factor, Phosphatidylinositol 3-Kinases -- Genetics, 0303 health sciences, Phosphoproteins -- Genetics, Protein Tyrosine Phosphatases -- Metabolism, Neoplastic -- Metabolism, Neoplastic -- Genetics, Platelet-Derived Growth Factor -- Metabolism, STAT Transcription Factors -- Genetics, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, rho GTP-Binding Proteins -- Metabolism, Signal Transduction, Protein Binding, Epithelial-Mesenchymal Transition, Neoplasm Proteins -- Genetics, Molecular Sequence Data, Phosphoproteins -- Metabolism, STAT Transcription Factors -- Metabolism, Neoplastic -- Pathology, Neoplasm Proteins -- Metabolism, 03 medical and health sciences, Phosphatidylinositol 3-Kinases -- Metabolism, Platelet-Derived Growth Factor -- Genetics, Humans, Integrins -- Genetics, Amino Acid Sequence, src-Family Kinases -- Genetics, Phosphotyrosine, Eph Family -- Metabolism, Eph Family -- Genetics, Protein Tyrosine Phosphatases -- Genetics, Cell Proliferation, Receptors, Eph Family, Neoplastic, Integrins -- Metabolism, Molecular Sequence Annotation, Phosphoproteins, Clone Cells, HEK293 Cells, Gene Expression Regulation, Protein Tyrosine Phosphatases

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/24030100
https://www.mcponline.org/article/S1535-9476(20)33839-1/fulltext
https://europepmc.org/article/MED/24030100
https://www.ncbi.nlm.nih.gov/pubmed/24030100
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24030100/
https://pubmed.ncbi.nlm.nih.gov/24030100/
https://www.sciencedirect.com/science/article/pii/S1535947620338391

Protein Kinase C Activation Stimulates Mesenchymal Stem Cell Adhesion through Activation of Focal Adhesion Kinase

Autoren: Eunmi Choi Woochul Chang Il-Kwon Kim et al.

Weitere Verfasser: Eunmi Choi Woochul Chang Il-Kwon Kim et al.

Quelle: Cell Transplantation, Vol 22 (2013)

Schlagwörter: Myocardium/pathology, Male, rho GTP-Binding Proteins, 0301 basic medicine, Integrins, Protein Kinase C/antagonists & inhibitors, Mesenchymal stem cells (MSCs), Myocardial Ischemia, Integrins/metabolism, Protein kinase C (PKC), Mesenchymal Stem Cell Transplantation, Rats, Sprague-Dawley, 03 medical and health sciences, Tetradecanoylphorbol Acetate/analogs & derivatives, rho GTP-Binding Proteins/metabolism, Cell Adhesion, Animals, Cell Adhesion/drug effects, Benzopyrans, Focal Adhesion Protein-Tyrosine Kinases/metabolism, Protein Kinase C, Transplantation, Myocardium, Tetradecanoylphorbol Acetate/pharmacology, Acetophenones/pharmacology, Acetophenones, Protein Kinase C/chemistry, Mesenchymal Stem Cells, Mesenchymal Stromal Cells/cytology, Ischemic heart, Protein Kinase C/metabolism, Rats, 3. Good health, Benzopyrans/pharmacology, Focal Adhesion Protein-Tyrosine Kinases, Myocardial Ischemia/therapy, Adhesion, Medicine, Tetradecanoylphorbol Acetate, Sprague-Dawley

Zugangs-URL: http://journals.sagepub.com/doi/pdf/10.3727/096368912X656126
https://pubmed.ncbi.nlm.nih.gov/23006313
https://doaj.org/article/7026603ac313460ca3bdaed76fa40081
https://journals.sagepub.com/doi/pdf/10.3727/096368912X656126
http://journals.sagepub.com/doi/10.3727/096368912X656126
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86904
https://pubmed.ncbi.nlm.nih.gov/23006313/
https://yonsei.pure.elsevier.com/en/publications/protein-kinase-c-activation-stimulates-mesenchymal-stem-cell-adhe
https://journals.sagepub.com/doi/full/10.3727/096368912X656126

Chronic lymphocytic leukemia cells induce defective LFA-1–directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide

Autoren: Ramsay, A. G. Evans, Rachel Kiaii, S. et al.

Quelle: Blood. 121:2704-2714

Schlagwörter: rac1 GTP-Binding Protein, rho GTP-Binding Proteins, Antineoplastic Agents/pharmacology Cell Movement/drug effects/immunology Coculture Techniques Humans Immunologic Factors/pharmacology Leukemia, T-Lymphocytes, Ubiquitin-Protein Ligases, Primary Cell Culture, Antineoplastic Agents, Cell Movement, Tumor Cells, Cultured, Humans, Immunologic Factors, Chronic, cdc42 GTP-Binding Protein, Lenalidomide, Adaptor Proteins, Signal Transducing, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphocytic, Coculture Techniques, Lymphocyte Function-Associated Antigen-1, Thalidomide, 3. Good health, B-Cell/*drug therapy/metabolism/pathology Lymphocyte Function-Associated Antigen-1/*metabolism Peptide Hydrolases/metabolism Primary Cell Culture Signal Transduction/*drug effects/immunology T-Lymphocytes/cytology/*drug effects/metabolism Thalidomide/*analogs & derivatives/pharmacology Tumor Cells, Cultured cdc42 GTP-Binding Protein/metabolism rac1 GTP-Binding Protein/metabolism rho GTP-Binding Proteins/*metabolism rhoA GTP-Binding Protein/metabolism, rhoA GTP-Binding Protein, Peptide Hydrolases, Signal Transduction

Zugangs-URL: https://ashpublications.org/blood/article-pdf/121/14/2704/1365440/2704.pdf
https://pubmed.ncbi.nlm.nih.gov/23325833
https://ashpublications.org/blood/article/121/14/2704/31146/Chronic-lymphocytic-leukemia-cells-induce
https://www.sciencedirect.com/science/article/pii/S0006497120473677
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617635/
http://europepmc.org/articles/PMC3617635

Sphingosine 1-Phosphate (S1P) Receptors 1 and 2 Coordinately Induce Mesenchymal Cell Migration through S1P Activation of Complementary Kinase Pathways*

Autoren: Sundeep Khosla Ming Ruan Moustapha Kassem et al.

Quelle: Quint, P, Ruan, M, Pederson, L, Kassem, M, Westendorf, J J, Khosla, S & Oursler, M J 2013, ' Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through s1p activation of complementary kinase pathways ', Journal of Biological Chemistry, vol. 288, no. 8, pp. 5398-5406 . https://doi.org/10.1074/jbc.M112.413583

Schlagwörter: rho GTP-Binding Proteins, 0301 basic medicine, Cell signaling, Cells, Inbred C57BL, Models, Biological, Mice, 03 medical and health sciences, Models, rho GTP-Binding Proteins/metabolism, Cell Movement, Osteogenesis, Receptors, Animals, Humans, Cell migration, Receptors, Lysosphingolipid/metabolism, Bone Resorption, Bone, Sphingosine-1-Phosphate Receptors, Cells, Cultured, Osteoblasts, Mesenchymal Stem Cells/cytology, Osteoblasts/cytology, spingosine 1 phosphate, Cultured/cytology, Mesenchymal Stem Cells, Biological, Mice, Inbred C57BL, Receptors, Lysosphingolipid, Osteoclast, Lysosphingolipid/metabolism, Cells, Cultured/cytology, Signal Transduction

Zugangs-URL: http://www.jbc.org/content/288/8/5398.full.pdf
https://pubmed.ncbi.nlm.nih.gov/23300082
https://pubmed.ncbi.nlm.nih.gov/23300082/
http://europepmc.org/articles/PMC3581421
https://mayoclinic.pure.elsevier.com/en/publications/sphingosine-1-phosphate-s1p-receptors-1-and-2-coordinately-induce
https://www.ncbi.nlm.nih.gov/pubmed/23300082
http://www.jbc.org/content/288/8/5398.full
https://www.jbc.org/article/S0021-9258(20)45043-4/fulltext
https://portal.findresearcher.sdu.dk/da/publications/2339d1a1-7fe6-48e6-8b32-e2ebed67408c
https://portal.findresearcher.sdu.dk/da/publications/2339d1a1-7fe6-48e6-8b32-e2ebed67408c
https://doi.org/10.1074/jbc.M112.413583