Search Results - "physiological functions"

ADAPTATION IN EXTREME STRESSFUL CONDITIONS: SOME TECHNOLOGIES OF STUDYING

Authors: P.V. Biloshitsky O.M. Klyuchko YU.M. Onopchuk et al.

Source: Biotechnologia Acta, Vol 18, Iss 1, Pp 16-29 (2025)

Subject Terms: numerical indices of physiological functions, extreme conditions, adaptation, stressful conditions, TP248.13-248.65, mathematical modeling, Biotechnology

Access URL: https://doaj.org/article/157f2672bd0a4f2fa02533686156db82

Stress granules: Guardians of cellular health and triggers of disease

Authors: Meghal Desai Keya Gulati Manasi Agrawal et al.

Source: Neural Regen Res
Neural Regeneration Research, Vol 21, Iss 2, Pp 588-597 (2026)

Subject Terms: stress granules, neurodevelopment, apoptosis, axon regeneration, neurodegeneration, translation, Review, mrna transport, biomolecular condensates, physiological functions, germline cell development, viral infection, Neurology. Diseases of the nervous system, RC346-429, pathophysiology

Access URL: https://pubmed.ncbi.nlm.nih.gov/39995077
https://doaj.org/article/3d4fcdf380f84657a265b40d9a7061b7

Correction: Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy

Authors: Bo Huang Qihang Yuan Jiaao Sun et al.

Source: Front Immunol
Frontiers in Immunology, Vol 16 (2025)

Subject Terms: tumorigenesis, Immunology, physiological functions, anticancer therapy, nucleotide metabolism, Immunologic diseases. Allergy, RC581-607, thymidine phosphorylase

Access URL: https://doaj.org/article/a66519bfb6534b2598f4d4c819189d8a

Decoding the dual regulatory systems: Contemporary insights into the lateral habenula and rostromedial tegmental nucleus physiology

Authors: Juntao Cui Junliang Qian Jun Wang et al.

Source: Neurobiology of Disease, Vol 214, Iss , Pp 107049- (2025)

Subject Terms: Lateral habenula, Rostromedial tegmental nucleus, Physiological functions, Neural circuit, Neuropsychiatric disorders, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996125002657; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/0951497187ac44afa7ae41751694ae41

Distribution of gut microbiota across intestinal segments and their impact on human physiological and pathological processes

Authors: Ke Yang Guangqin Li Qihong Li et al.

Source: Cell & Bioscience, Vol 15, Iss 1, Pp 1-24 (2025)

Subject Terms: Gut microbiota, Intestinal segments, Distribution characteristics, Physiological functions, Pathological processes, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/99d0201be8974d6d95e104e399c0dd46

A review of sphingolipids from marine sources and their analytical method, metabolic process, and essential roles in human health

Authors: Xinwen Wang Mantong Zhao Guanghua Xia et al.

Source: Food Frontiers, Vol 5, Iss 5, Pp 2015-2042 (2024)

Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, metabolism process, Nutrition. Foods and food supply, analytical method, physiological functions, TX341-641, TP368-456, human health, marine sphingolipids, Food processing and manufacture

Access URL: https://doaj.org/article/519a1727bcb24fcb8f336964c362b5c9

Exploring the diversity of biological processes regulated by glial cell line-derived neurotrophic factor, a pleiotropic molecule with therapeutic potential

Authors: Cristina Porcari Stefano Cattaneo Lucia Crippa et al.

Source: Front Physiol
Frontiers in Physiology, Vol 16 (2025)

Subject Terms: astrocytic GDNF, GDNF (glial cell line-derived neurotrophic factor), GDNF physiological functions, GDNF role in the CNS, GDNF secretion, GDNF signaling, Physiology, QP1-981

File Description: application/pdf

Access URL: https://doaj.org/article/7fc25ba59c154832aa5ad023837c00d4

Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy

Authors: Bo Huang Qihang Yuan Jiaao Sun et al.

Source: Front Immunol
Frontiers in Immunology, Vol 16 (2025)

Subject Terms: Thymidine Phosphorylase, Carcinogenesis, Nucleotides, Immunology, Antineoplastic Agents, nucleotide metabolism, RC581-607, thymidine phosphorylase, tumorigenesis, Neoplasms, Humans, Animals, physiological functions, anticancer therapy, Immunologic diseases. Allergy

Access URL: https://pubmed.ncbi.nlm.nih.gov/40303404
https://doaj.org/article/ea3ee37bcabe49ecada0c9450cae3f44

PARP (Poly ADP‐ribose Polymerase) Family in Health and Disease

Authors: Pengyuan Lei Wenfeng Li Jinhua Luo et al.

Source: MedComm, Vol 6, Iss 9, Pp n/a-n/a (2025)

Subject Terms: PARP family, physiological functions, pathological mechanisms, DNA damage repair, metabolic regulation, PARP‐targeted therapy, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/6abb2a85c8784fa2b2979d1ab000bf8b

Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases

Authors: Jing Jin Yurou Wang Yueqin Liu et al.

Source: Acta Pharm Sin B
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1483-1493 (2024)

Subject Terms: Spatiotemporal distribution, 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Cardiac development, Physiological functions, Therapeutics. Pharmacology, RM1-950, Review, Cardiac homeostasis, Research tools, Cardiac resident macrophages

Access URL: https://pubmed.ncbi.nlm.nih.gov/38572111
https://doaj.org/article/0bd9797a40934f518ca2dcd8b4e67fe6

AGE SPORT AND AGING

Authors: Romanovich, V.A.

Source: Practice Oriented Science: UAE – RUSSIA – INDIA.

Subject Terms: Sports veterans, aging, physical activity, physiological functions, 16. Peace & justice, 10. No inequality, telomeres, 3. Good health

Circular RNAs in Cervical Cancer: What are the Prospects?

Authors: S. A. Begliarzade R. I. Tamrazov

Source: Креативная хирургия и онкология, Vol 13, Iss 4, Pp 320-329 (2023)

Subject Terms: 0301 basic medicine, rna-binding protein, 0303 health sciences, RD1-811, cervical cancer, circular rna, biomarkers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, biogenesis, 3. Good health, 03 medical and health sciences, circrna, physiological functions, Surgery, human papillomavirus, RC254-282

Access URL: https://doaj.org/article/925e5a27c49d4bf7aa80d7fb542d098a

An Engineered Supramolecular Fluorescent Chemosensor for Multiscale Visualization of Glutamate Dynamics in Living Systems

Authors: Yuxiao Mei Jing Sun Zhichao Liu et al.

Subject Terms: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Physiology, Biotechnology, Mental Health, Computational Biology, Physical Sciences not elsewhere classified, optimized supramolecular chemosensor, indicator displacement method, glutamatergic activity ranging, altered glutamatergic signals, living systems glutamate, hypoxic mice compared, adjacent brain regions, monitoring glu dynamics, glutamate dynamics, normal mice, glu dynamics, thalamic populations, subcellular compartments, physiological functions, pathological processes, noise ratio, neuronal organelles, n <, multiscale visualization

Relation: https://figshare.com/articles/journal_contribution/An_Engineered_Supramolecular_Fluorescent_Chemosensor_for_Multiscale_Visualization_of_Glutamate_Dynamics_in_Living_Systems/30041421

Availability: https://doi.org/10.1021/jacs.5c11915.s001
https://figshare.com/articles/journal_contribution/An_Engineered_Supramolecular_Fluorescent_Chemosensor_for_Multiscale_Visualization_of_Glutamate_Dynamics_in_Living_Systems/30041421

Prediction of Activity and Selectivity Profiles of Sigma Receptor Ligands Using Machine Learning Approaches

Authors: Lisa Lombardo Verena Battisti Thierry Langer et al.

Subject Terms: Biochemistry, Cell Biology, Molecular Biology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, various biological pathways, support vector machine, ligand recognition mechanisms, distinct physiological functions, central nervous system, >- nearest neighbors, step multiclassification approach, s2r mainly expressed, best predictive performance, various ml algorithms, quality data sets, extra trees combined, identifying selective ligands, external validation procedure, extra trees, data sets, s2r ligands, external validation, sr ligands, selective s1r, validation protocols, two subtypes, therapeutic design

Relation: https://figshare.com/articles/journal_contribution/Prediction_of_Activity_and_Selectivity_Profiles_of_Sigma_Receptor_Ligands_Using_Machine_Learning_Approaches/30022944

Availability: https://doi.org/10.1021/acs.jcim.5c01091.s002
https://figshare.com/articles/journal_contribution/Prediction_of_Activity_and_Selectivity_Profiles_of_Sigma_Receptor_Ligands_Using_Machine_Learning_Approaches/30022944

Molecular Optimization of a Near-Infrared Fluorogenic Probe for Hydrogen Polysulfide Imaging in Acute Liver Injury

Authors: Zheng Wen Wei Peng Yongzhi Qi et al.

Subject Terms: Biochemistry, Cell Biology, Molecular Biology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, play pivotal roles, hydrogen polysulfide imaging, fluorescent “ turn, exceptional photophysical properties, excellent optical properties, dicyanoisophorone scaffold functionalized, cell death regulation, n , 2 , present probe dcicl, infrared fluorogenic probe, infrared fluorogenic, vivo <, probe employed, probe dcicl, >< sub, ” signal, upon reaction, results revealed, potential biomarker, physiological functions, oral administration, negative correlation

Availability: https://doi.org/10.1021/acs.analchem.5c00931.s001
https://figshare.com/articles/journal_contribution/Molecular_Optimization_of_a_Near-Infrared_Fluorogenic_Probe_for_Hydrogen_Polysulfide_Imaging_in_Acute_Liver_Injury/29442254

A Bayesian Optimization-Based Hybrid Deep Prediction Method for Zinc-Binding Protein Interaction Sites

Authors: Hui Li Fengxin Zhang Dechang Pi et al.

Subject Terms: Biophysics, Biochemistry, Medicine, Molecular Biology, Pharmacology, Computational Biology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, dynamically set weights, proposed method outperform, optimal combined model, normal physiological functions, better predictive power, 4 – 20, bayesian weighted optimization, bayesian optimization, nearly 4, method utilizes, metalloprotein functions, component model, better promote, thereby showing, proteins plays, protein sequence, prediction accuracy, performance metrics, paper proposes, new drugs, life activities, findings help

Availability: https://doi.org/10.1021/acs.jcim.5c00721.s001
https://figshare.com/articles/journal_contribution/A_Bayesian_Optimization-Based_Hybrid_Deep_Prediction_Method_for_Zinc-Binding_Protein_Interaction_Sites/29413510

Activatable Proximity-Labeled Fluorogenic Probe for Visualizing the Role of Estrogen in Regulating Liver Carboxylesterase Expression

Authors: Ningge Xu Jianqiang Ge Kaibo Huang et al.

Subject Terms: Biochemistry, Medicine, Cell Biology, Genetics, Physiology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, widely distributed drug, western blot analysis, spectral response properties, regulating physiological functions, refining drug therapy, personalized drug therapy, ovariectomized mouse model, different physiological conditions, cell lines based, additional experiments revealed, labeled fluorogenic probe, emitting fluorescence signals, mc exhibited superior, e2 modulates ces, ces particularly important, probe reacted, fluorescence imaging, ces levels, ces expression, ces activity, ces )

Availability: https://doi.org/10.1021/acs.analchem.5c01433.s001
https://figshare.com/articles/journal_contribution/Activatable_Proximity-Labeled_Fluorogenic_Probe_for_Visualizing_the_Role_of_Estrogen_in_Regulating_Liver_Carboxylesterase_Expression/29364187

Skin-Interfaced Entirely Self-Contained Wearable Biosensor for the Noninvasive and Dynamic Monitoring of Sweat Myo-Inositol

Authors: Wei Deng Jing Bai Ming Zhou

Subject Terms: Biochemistry, Medicine, Cell Biology, Molecular Biology, Physiology, Pharmacology, Sociology, sup >+, intrusive blood draws, interfaced entirely self, dose – response, automated microfluidic unit, physiological function modulation, contained wearable biosensor, demand sweat extraction, automated sweat sampling, intelligent control unit, sweat analysis unit, personalized health management, iontophoresis unit, physiological functions, personalized monitoring, health assessment, control experiments, inositol biosensor, inositol analysis, sweat myo, unique capacity, time monitoring, signal processing

Availability: https://doi.org/10.1021/acssensors.5c01284.s001
https://figshare.com/articles/journal_contribution/Skin-Interfaced_Entirely_Self-Contained_Wearable_Biosensor_for_the_Noninvasive_and_Dynamic_Monitoring_of_Sweat_Myo-Inositol/29225999

High-Precision Separation and Refinement of Fatty Acid Derivatives by Metal–Organic Frameworks

Authors: Akihiro Torimoto Daiki Ishibashi Atsushi Yamashita et al.

Subject Terms: Biophysics, Biochemistry, Medicine, Molecular Biology, Biotechnology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, unprecedented recognition mechanism, c  c, based recognition mechanism, associated process contaminants, purification methods lack, configured nanopores enable, fatty acid derivatives, chain fa derivatives, fatty acid, z <, unsaturated bond, two pillared, thermodynamic analysis, structural variations, stationary phases, specific multi, site interactions, resolution separation, precision separation, precise separation, physiological functions, necessary resolution

Availability: https://doi.org/10.1021/jacs.5c03316.s001
https://figshare.com/articles/journal_contribution/High-Precision_Separation_and_Refinement_of_Fatty_Acid_Derivatives_by_Metal_Organic_Frameworks/29008928

Regulate Ion Transport in Subnanochannel Membranes by Ion-Pairing

Authors: Rongming Xu Hang Yu Jiachun Ren et al.

Subject Terms: Biophysics, Biochemistry, Microbiology, Inorganic Chemistry, Mental Health, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, various practical applications, sustaining physiological functions, reflecting conditions closer, pair formation within, offers valuable insights, holds immense potential, biological ion channels, 3 , regulate ion transport, ion transport mechanisms, 2 +, regulating ion transport, ion transport, thereby regulating, 2 orders, ion recognition, world systems, thereby modulating, target ions, tailored responsiveness, subnanochannel membranes, stimulus ions

Availability: https://doi.org/10.1021/jacs.5c02722.s001
https://figshare.com/articles/journal_contribution/Regulate_Ion_Transport_in_Subnanochannel_Membranes_by_Ion-Pairing/28943950