Výsledky vyhľadávania - "molecular chaperone"

Optimizing longifolene production in Yarrowia lipolytica via metabolic and protein engineering

Autori: Yi-Tong Yao Xiao Zhang Chen-Yu Wang a ďalší

Zdroj: Synth Syst Biotechnol
Synthetic and Systems Biotechnology, Vol 10, Iss 2, Pp 433-441 (2025)

Predmety: Yarrowia lipolytica, Sesquiterpene, Longifolene, QH301-705.5, Molecular chaperone, Isopentenol utilization pathway, Protein engineering, Original Research Article, Biology (General), TP248.13-248.65, Biotechnology

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39925943
https://doaj.org/article/94c4b81def5a47faaf7a8d3c6dd747ce

Cerebrospinal fluid HSP90AA1, HSPA4, and STUB1/CHIP levels in Alzheimer's disease, mild cognitive impairment, and frontotemporal dementia

Autori: Pelin Sordu Merve Alaylıoğlu Bedia Samancı a ďalší

Prispievatelia: Pelin Sordu Merve Alaylıoğlu Bedia Samancı a ďalší

Zdroj: Journal of Alzheimer’s Disease. 105:481-493

Predmety: Male, Aged, 80 and over, Amyloid beta-Peptides, Ubiquitin-Protein Ligases, heat shock protein, tau Proteins, Alzheimer's disease, molecular chaperone, Middle Aged, cerebrospinal fluid, Alzheimer Disease, Frontotemporal Dementia, biomarker, chaperone, Humans, Cognitive Dysfunction, Female, HSP90 Heat-Shock Proteins, STUB1/CHIP chaperone protein, APOE, Biomarkers, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40116694

Engineered Folding and Secretion for Expression Improvement of α‐Amylase in Komagataella Phaffii

Autori: Yilun Zhang Xingbin Wang Bei Han a ďalší

Zdroj: Food Bioengineering, Vol 4, Iss 1, Pp 3-14 (2025)

Predmety: α‐amylase, vesicle transport factor, molecular chaperone, TP368-456, K. phaffii, multicopy, Food processing and manufacture

Prístupová URL adresa: https://doaj.org/article/a47eef71803543fa8aeddd78393448a8

BiP, GRP94, calreticulin and calnexin contribute to development of the notochord in medaka fish

Autori: Serina Kita Tokiro Ishikawa Kazutoshi Mori

Zdroj: Cell Structure and Function, Vol 50, Iss 1, Pp 125-133 (2025)

Predmety: collagen, glycoprotein, endoplasmic reticulum, QH301-705.5, protein folding, Science, molecular chaperone, Biology (General)

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40368802
https://doaj.org/article/cac7070289e84c0da08cc012d619e738

Molecular basis for different substrate-binding sites and chaperone functions of the BRICHOS domain

Autori: Chen, Gefei Wang, Yu Zheng, Zihan a ďalší

Zdroj: Protein Science. 33(7)

Predmety: BRICHOS, fibrillar and amorphous aggregation, molecular chaperone, oligomer model

Popis súboru: print

Prístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-348308
https://doi.org/10.1002/pro.5063

Heat shock protein family H member 1 HSPH1 expression correlates with progression and prognosis of hepatocellular carcinoma

Autori: Tianyi Huang Shimeng Xu Ming Li a ďalší

Zdroj: Scientific Reports, Vol 15, Iss 1, Pp 1-16 (2025)

Predmety: HSPH1, Hepatocellular carcinoma, Prognosis, Immune infiltration, Biomarker, Molecular chaperone, Medicine, Science

Popis súboru: electronic resource

Relation: https://doaj.org/toc/2045-2322

Prístupová URL adresa: https://doaj.org/article/ec8d04a1eb0d48dfa777105ad7ec8e5e

Biochemical and biophysical characterization of Plasmodium falciparum glucose regulated protein 170

Autori: Florence Lisa Muzenda Melissa Louise Stofberg Wendy Mthembu a ďalší

Zdroj: Scientific Reports, Vol 15, Iss 1, Pp 1-17 (2025)

Predmety: Malaria, Plasmodium falciparum, PfGrp170/PfHsp70-y, Hsp110, Molecular chaperone, Medicine, Science

Popis súboru: electronic resource

Relation: https://doaj.org/toc/2045-2322

Prístupová URL adresa: https://doaj.org/article/78378ed9a842482e876f534510ad0f94

ClpB chaperone as a promising target for antimicrobial therapy: A narrative review

Autori: Sachini J. Udari Sayoka Shamodhi Rumesh M. Nelumdeniya a ďalší

Zdroj: Asian Pacific Journal of Tropical Biomedicine, Vol 15, Iss 1, Pp 1-10 (2025)

Predmety: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, clpb, plasmodium falciparum, QH301-705.5, Arctic medicine. Tropical medicine, heat shock proteins, RC955-962, eskape pathogens, molecular chaperone, Biology (General), thermotolerance

Prístupová URL adresa: https://doaj.org/article/81d217a216c94285b393009a1fc628b1

Molecular chaperone effects on recombinant yield and binding characteristics of an ABA-specific scFv in Escherichia coli

Autori: Shimiao Chen Bin Shan Yican Luo a ďalší

Zdroj: Frontiers in Bioengineering and Biotechnology, Vol 13 (2025)

Predmety: ABA-scFv, molecular chaperone, Escherichia coli, soluble expression, antibody specificity, Biotechnology, TP248.13-248.65

Popis súboru: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2025.1643833/full; https://doaj.org/toc/2296-4185

Prístupová URL adresa: https://doaj.org/article/bf36c0427491411993a779ff411d762e

Prediction of lipase-specific foldase-dependence in bacterial lipase subfamilies I.1 and I.2

Autori: Takahiro Hioki

Zdroj: BMC Genomics, Vol 26, Iss 1, Pp 1-11 (2025)

Predmety: Bacterial lipase, Lipase-specific foldase, Molecular chaperone, Phylogenetic analysis, Heterologous expression, Biotechnology, TP248.13-248.65, Genetics, QH426-470

Popis súboru: electronic resource

Relation: https://doaj.org/toc/1471-2164

Prístupová URL adresa: https://doaj.org/article/82efcb2354f04cd3870d02139f34e910

The calcium-binding protein S100B as a novel chaperone preventing Tau aggregation in Alzheimer’s disease

Autori: Moreira, Guilherme G. Gomes, Cláudio Emanuel Moreira Repositório Científico de Acesso Aberto da ULisboa

Prispievatelia: Moreira, Guilherme G. Gomes, Cláudio Emanuel Moreira Repositório Científico de Acesso Aberto da ULisboa

Zdroj: urn:tid:101764073

Predmety: Alzheimer's disease, Protein aggregation, Tau, S100B protein, Molecular chaperone, Doença de Alzheimer, Agregação proteica, Proteína S100B, Chaperona molecular

Popis súboru: application/pdf

Dostupnosť: http://hdl.handle.net/10400.5/101426

Structural insights of the p97/VCP AAA+ ATPase: How adapter interactions coordinate diverse cellular functionality.

Autori: Braxton, Julian Southworth, Daniel

Zdroj: Journal of Biological Chemistry. 299(11)

Predmety: AAA+ ATPase, AlphaFold, ERAD, VCP, adapter, adaptor, autophagy, cofactor, cryo-EM, molecular chaperone, p97, protein structure prediction, proteostasis, unfoldase, Humans, Adaptor Proteins, Signal Transducing, Valosin Containing Protein, Protein Folding, Protein Domains, Models, Molecular, Protein Structure, Quaternary

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/2ws2c3gq
https://escholarship.org/content/qt2ws2c3gq/qt2ws2c3gq.pdf

Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer.

Autori: Ahanin, Elham Sager, Rebecca Backe, Sarah a ďalší

Zdroj: Cell chemical biology. 30(10)

Predmety: FADD, clear cell renal cell carcinoma, co-chaperone, extrinsic apoptotic pathway, heat shock protein-90, molecular chaperone, serine/threonine phosphatase-5, Humans, Phosphoprotein Phosphatases, Nuclear Proteins, Apoptosis, Kidney Neoplasms

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/81p943ck
https://escholarship.org/content/qt81p943ck/qt81p943ck.pdf

o8G-modified circPLCE1 inhibits lung cancer progression via chaperone-mediated autophagy

Autori: Qingyun Zhao Dunyu Cai Haotian Xu a ďalší

Zdroj: Molecular Cancer, Vol 24, Iss 1, Pp 1-26 (2025)

Predmety: CircRNA, O8G modification, HSC70, Molecular chaperone-mediated autophagy, Lung cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Popis súboru: electronic resource

Relation: https://doaj.org/toc/1476-4598

Prístupová URL adresa: https://doaj.org/article/8141892809b54f0da834228ceb58c134

CNPY3 Promotes Human Breast Cancer Progression and Metastasis via Modulation of the Tumor Microenvironment

Autori: Xiaofeng Duan Ran Zhao Shaoli Sun a ďalší

Zdroj: Current Issues in Molecular Biology, Vol 47, Iss 11, p 883 (2025)

Predmety: CNPY3, molecular chaperone, therapeutic target, unfolded protein response, tumor microenvironment, Biology (General), QH301-705.5

Popis súboru: electronic resource

Relation: https://www.mdpi.com/1467-3045/47/11/883; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Prístupová URL adresa: https://doaj.org/article/845d9a48607d42bfac16082604da4d04

ATP-independent molecular chaperone activity generated under reducing conditions

Autori: Leppert, Axel Chen, Gefei Lianoudaki, Danai a ďalší

Zdroj: Protein Science. 31(8)

Predmety: ATP-independent molecular chaperone, Bri2 BRICHOS, BRICHOS domain, disulfide bond formation, extracellular protein aggregation

Popis súboru: electronic

Prístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-198486
https://doi.org/10.1002/pro.4378

Structural and functional aspects of the interaction partners of the small heat-shock protein in Synechocystis

Autori: Marklund, Erik G., Teknologie doktor Zhang, Yichen Basha, Eman a ďalší

Zdroj: Cell stress & chaperones (Print). 23(4):723-732

Predmety: Bioinformatics, Cyanobacteria, Molecular chaperone, Small heat-shock protein, α-Crystallins, Bioinformatik

Popis súboru: electronic

Prístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343347
https://doi.org/10.1007/s12192-018-0884-3

A short review on introduction and researches on anticancerous activity of geldanamycin

Autori: Sami, Hesham Gour, Rajesh Singhai, Akhlesh Kumar

Zdroj: Asian Journal of Pharmacy and Technology 14(3):220-224. 2024

MECHANISMS OF HSPA1A EXPORT TO THE EXTRACELLULAR MEDIUM IN HEAT-SHOCKED CELLS

Autori: Badolian, Allen orcid:0009-0008-4401- Nikolaidis, Nikolas a ďalší

Prispievatelia: Badolian, Allen orcid:0009-0008-4401- Nikolaidis, Nikolas a ďalší

Predmety: molecular chaperone, cellular stress, Hsp70, extracellular membrane (EM), extracellular vesicles, lysosome

Relation: https://zenodo.org/communities/csuf/; https://zenodo.org/records/15460255; oai:zenodo.org:15460255; https://doi.org/10.5281/zenodo.15460255

Dostupnosť: https://doi.org/10.5281/zenodo.15460255
https://zenodo.org/records/15460255

A Disease-Associated Mutation Impedes PPIA through Allosteric Dynamics Modulation

Autori: Yoshikazu Hattori Munehiro Kumashiro Hiroyuki Kumeta a ďalší

Predmety: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, theoretical kinetic analysis, structure remain unclear, motor neuron degeneration, molecular chaperone involved, approximately 1 order, allosteric network essential, maintaining proper folding, sporadic als patients, k76e arises primarily, direct structural disruption, recent study identified, protein folding, wild type, used biochemical, substrate recognition, significant effects, results show, related proteins

Dostupnosť: https://doi.org/10.1021/acs.biochem.5c00260.s001
https://figshare.com/articles/journal_contribution/A_Disease-Associated_Mutation_Impedes_PPIA_through_Allosteric_Dynamics_Modulation/29438541