Výsledky vyhľadávania - "genotype 1a"

High real-world effectiveness of 12-week elbasvir/grazoprevir without resistance testing in the treatment of patients with HCV genotype 1a infection in Norway

Autori: Leiva, R. A. Bergersen, B. M. Finbråten, A. K. a ďalší

Zdroj: Scandinavian Journal of Gastroenterology. 58(3):264-268

Predmety: Infectious Medicine, Infektionsmedicin, direct-acting antiviral agents, elbasvir, grazoprevir, HCV genotype 1a, NS5A RAS

Prístupová URL adresa: https://gup.ub.gu.se/publication/322503

Prevalence of NS5A resistance associated substitutions in patients with hepatitis C virus genotypes 1a and 3: Impact on current therapeutic strategies: Impact on current therapeutic strategies

Autori: Marta Grandal Berta Pernas Andrés Tabernilla a ďalší

Prispievatelia: Marta Grandal Berta Pernas Andrés Tabernilla a ďalší

Zdroj: RUC. Repositorio da Universidade da Coruña
instname

Predmety: RASs, Adult, Male, 0301 basic medicine, Genotype, Ribavirin/pharmacology, Mutation, Missense, Mutación missense, Antiviral Agents/pharmacology, Hepacivirus, Viral Nonstructural Proteins, Proteínas mutantes, NS5A, Antiviral Agents, 03 medical and health sciences, Hepatitis C, Chronic/drug therapy, Drug Resistance, Viral, Ribavirin, Prevalence, Humans, genotype 3, Sustitución de aminoácidos, Farmacorresistencia viral, Genotype 1a, Análisis de secuencia de ADN, Ribavirina, Sequence Analysis, DNA, Genotype 3, Hepatitis C, Chronic, Middle Aged, genotype 1a, 3. Good health, Viral Nonstructural Proteins/genetics, Amino Acid Substitution, Antivirales, Mutant Proteins, Mutant Proteins/genetics, Prevalencia, HCV-infection, Genotipo, Hepacivirus/classification, Hepatitis C crónica, Follow-Up Studies

Popis súboru: application/pdf

Prístupová URL adresa: https://ruc.udc.es/dspace/bitstream/2183/20798/2/Grndal_Prvlence.pdf
https://pubmed.ncbi.nlm.nih.gov/29427437
http://hdl.handle.net/2183/20798
https://onlinelibrary.wiley.com/doi/10.1002/jmv.25048
https://pubmed.ncbi.nlm.nih.gov/29427437/
https://www.ncbi.nlm.nih.gov/pubmed/29427437
https://hdl.handle.net/2183/20798
https://hdl.handle.net/10668/12111
https://biblio.vub.ac.be/vubir/(c980fe18-9b60-4b2f-a117-6b7b6e60b7ee).html

Phylogenetic Diversity in Core Region of Hepatitis C Virus Genotype 1a as a Factor Associated with Fibrosis Severity in HIV-1-Coinfected Patients

Autori: Micaela Parra Natalia Laufer Julieta M. Manrique a ďalší

Zdroj: Biomed Res Int
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas

Predmety: Liver Cirrhosis, Male, 0301 basic medicine, Genotype, Liver fibrosis, HIV Infections, Hepacivirus, phylogeny, 03 medical and health sciences, Risk Factors, Humans, Phylogeny, 0303 health sciences, Coinfection, core, HIV, Genetic Variation, Interferon-alpha, Hepatitis C, Chronic, genotype 1a, 3. Good health, HCV, HIV-1, Female, Research Article

Popis súboru: text/xhtml; application/pdf

Prístupová URL adresa: http://downloads.hindawi.com/journals/bmri/2017/1728456.pdf
https://pubmed.ncbi.nlm.nih.gov/29259976
https://www.ncbi.nlm.nih.gov/pubmed/29259976
https://core.ac.uk/display/132174632
https://doi.org/10.1155/2017/1728456
https://www.hindawi.com/journals/bmri/2017/1728456/
https://ri.conicet.gov.ar/handle/11336/47446
http://downloads.hindawi.com/journals/bmri/2017/1728456.pdf
http://hdl.handle.net/11336/47446

The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors

Autori: Lambert, SM Langley, DR Garnett, JA a ďalší

Zdroj: Protein Sci

Predmety: 0301 basic medicine, 2. Zero hunger, 0303 health sciences, Pyrrolidines, Genotype 1a, Genotype, Crystal structure, Imidazoles, Valine, Articles, Hepacivirus, Hepititis virus, Viral Nonstructural Proteins, NS5a, Crystallography, X-Ray, Antiviral Agents, 3. Good health, Daclatasvir, 03 medical and health sciences, Drug Resistance, Viral, Carbamates

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/24639329
http://europepmc.org/articles/PMC4093949
https://www.ncbi.nlm.nih.gov/pubmed/24639329
https://core.ac.uk/display/76995325
https://onlinelibrary.wiley.com/doi/10.1002/pro.2456
https://spiral.imperial.ac.uk:8443/bitstream/10044/1/18806/2/The%20crystal%20structure%20of%20NS5A%20domain%201%20from%20genotype%201a%20reveals%20new%20clues%20to%20the%20mechanism%20of%20action%20for%20dimeric%20HCV%20inhibitors..pdf
https://onlinelibrary.wiley.com/doi/pdf/10.1002/pro.2456
http://hdl.handle.net/10044/1/18806

Phylogeography and epidemiological history of West Nile virus genotype 1a in Europe and the Mediterranean basin

Autori: G. Zehender E. Ebranati F. Bernini a ďalší

Zdroj: Infection, Genetics and Evolution. 11:646-653

Predmety: 0301 basic medicine, Likelihood Functions, 0303 health sciences, Genotype, Mediterranean Region, WEST NILE VIRUS GENOTYPE 1A, SPATIO TEMPORAL PHYLODYNAMICS, BAYESIAN PHYLOGEOGRAPHY, WNV 2008/2009 ITALIAN EPIDEMIC, MIGRATORY BIRDS, Bayes Theorem, History, 20th Century, 3. Good health, Europe, Phylogeography, 03 medical and health sciences, West Nile virus genotype 1a, spatio temporal phylodynamics, Bayesian phylogeography, WNV 2008/2009 Italian epidemic, migratory birds, Mediterranean WNV, Humans, West Nile virus, Phylogeny, West Nile Fever

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/21320643
https://www.sciencedirect.com/science/article/pii/S1567134811000281
https://www.ncbi.nlm.nih.gov/pubmed/21320643
https://hdl.handle.net/20.500.11768/157070
https://doi.org/10.1016/j.meegid.2011.02.003
https://hdl.handle.net/2434/160535
https://doi.org/10.1016/j.meegid.2011.02.003
https://hdl.handle.net/11585/102239
https://doi.org/10.1016/j.meegid.2011.02.003

Resistance-associated polymorphisms in Dutch hepatitis C genotype 1a patients with and without HIV infection

Autori: Faydra I. Lieveld Niels Swaans Astrid M. Newsum a ďalší

Zdroj: Annals of Hepatology, Vol 15, Iss 5, Pp 696-704 (2016)

Predmety: Hepatitis C virus, HIV, Genotype 1a, Q80K, Drug resistance, Specialties of internal medicine, RC581-951

Popis súboru: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268119306313; https://doaj.org/toc/1665-2681

Prístupová URL adresa: https://doaj.org/article/ef7f7c7b6ddf4c0f9a907447d000c29e

Replication of a novel subgenomic HCV genotype 1a replicon expressing a puromycin resistance gene in Huh-7 cells

Autori: Liang, CY Rieder, E Hahm, B a ďalší

Prispievatelia: Liang, CY Rieder, E Hahm, B a ďalší

Zdroj: Virology. 333:41-53

Predmety: hepatitis C virus, 0301 basic medicine, NONTRANSLATED REGION, Genotype, RIBOSOMAL ENTRY SITE, Hepacivirus, HEPATITIS-C VIRUS, Virus Replication, Antiviral Agents, CULTURE, INITIATION, 03 medical and health sciences, Genotype 1a replicon, Virology, Cell Line, Tumor, Drug Resistance, Viral, ELEMENTS, puromycin resistance gene, EPIDEMIOLOGY, Humans, INTERFERON-ALPHA-2B, ADAPTIVE MUTATIONS, CDNA-CLONE, 0303 health sciences, EFFICIENT REPLICATION, Hepatitis C virus, Puromycin resistance gene, 3. Good health, GENOME, genotype 1a replicon, Mutation, VIRAL-RNA REPLICATION, RNA, Viral, RNA replication, Puromycin, Replicon

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/15708591
https://www.sciencedirect.com/science/article/abs/pii/S0042682204008724
https://europepmc.org/abstract/MED/15708591
https://core.ac.uk/display/81209342
https://www.sciencedirect.com/science/article/pii/S0042682204008724
https://www.ncbi.nlm.nih.gov/pubmed/15708591

Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients

Autori: Nora A Fierro Karina González-Aldaco Rafael Torres-Valadez a ďalší

Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 2, Pp 267-271 (2015)

Predmety: hepatitis C virus, cytokines, viral clearance, genotype 1a, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216

Popis súboru: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000200267&lng=en&tlng=en; https://doaj.org/toc/1678-8060

Prístupová URL adresa: https://doaj.org/article/220d6a2fd12949c1981ddc45190123dd

Inter and intra-host variability of hepatitis C virus genotype 1a hypervariable envelope coding domains followed for a 4–11 year of human immunodeficiency virus coinfection and highly active antiretroviral therapy

Autori: Natalia Laufer Franco Moretti Jorge Quarleri a ďalší

Zdroj: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas

Predmety: Adult, Male, 0301 basic medicine, Viral diversity, HAART, Genotype, Anti-HIV Agents, HIV Infections, Hepacivirus, Host Specificity, 03 medical and health sciences, Viral Envelope Proteins, Virology, Antiretroviral Therapy, Highly Active, Humans, Amino Acid Sequence, Phylogeny, 0303 health sciences, Genotype 1a, HIV coinfection, Genetic Variation, Middle Aged, Hepatitis C, 3. Good health, HVR-1, Amino Acid Substitution, HCV, Female, Quasispecies heterogeneity

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/25461527
https://notablesdelaciencia.conicet.gov.ar/handle/11336/30746
https://ri.conicet.gov.ar/handle/11336/30746
https://www.sciencedirect.com/science/article/pii/S0042682214004280
https://core.ac.uk/display/82730213
https://www.ncbi.nlm.nih.gov/pubmed/25461527/
http://hdl.handle.net/11336/30746

Variability and resistance mutations in the hepatitis C virus NS3 protease in patients not treated with protease inhibitors

Autori: Zeminian, Luciana Bonome Padovani, Juliana Lara Corvino, Sílvia Maria a ďalší

Prispievatelia: Zeminian, Luciana Bonome Padovani, Juliana Lara Corvino, Sílvia Maria a ďalší

Zdroj: Mem Inst Oswaldo Cruz
Memorias do Instituto Oswaldo Cruz, Vol 108, Iss 1, Pp 13-17 (2013)
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Memórias do Instituto Oswaldo Cruz, Volume: 108, Issue: 1, Pages: 13-17, Published: FEB 2013

Predmety: Adult, Male, 0301 basic medicine, Genotype, protease inhibitors, Infectious and parasitic diseases, RC109-216, Hepacivirus, Viral Nonstructural Proteins, Microbiology, Antiviral Agents, 03 medical and health sciences, NS3 protease mutations, Drug Resistance, Viral, Ribavirin, Humans, Polymorphism, Genetic, Articles, Hepatitis C, Chronic, Middle Aged, QR1-502, 3. Good health, HCV genotype 1a, Mutation, RNA, Viral, Female, Interferons

Popis súboru: text/html

Prístupová URL adresa: http://www.scielo.br/pdf/mioc/v108n1/02.pdf
https://pubmed.ncbi.nlm.nih.gov/23440108
https://doaj.org/article/02987132bc22495e9817b512af2a5903
https://doaj.org/article/281ab9a7b6674c6f80ae894b5f792026
http://europepmc.org/articles/PMC3974320
https://www.scielo.br/scielo.php?pid=S0074-02762013000100002&script=sci_arttext&tlng=es
https://pubmed.ncbi.nlm.nih.gov/23440108/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974320/
http://repositorio.unesp.br/handle/11449/11553
http://www.scielo.br/pdf/mioc/v108n1/02.pdf
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100002&lng=en&tlng=en

Longitudinal analysis of the 5′UTR, E2-PePHD and NS5A-PKRBD genomic regions of hepatitis C virus genotype 1a in association with the response to peginterferon and ribavirin therapy in HIV-coinfected patients

Autori: Natalia Laufer Lucila Cassino Rita Reynoso a ďalší

Zdroj: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas

Predmety: Adult, Male, 0301 basic medicine, Molecular Sequence Data, HIV Infections, Hepacivirus, Viral Nonstructural Proteins, Antiviral Agents, 03 medical and health sciences, Viral Envelope Proteins, Drug Resistance, Viral, Ribavirin, Humans, GENOTYPE 1A, Amino Acid Sequence, Treatment Failure, Base Sequence, HIV, Hepatitis C, Chronic, Middle Aged, PEGYLATED INTERFERON, 3. Good health, HCV, Female, Interferons, RIBAVIRIN, 5' Untranslated Regions, Sequence Alignment

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/22683884
https://www.sciencedirect.com/science/article/pii/S0166354212001301
http://www.ncbi.nlm.nih.gov/pubmed/22683884
https://europepmc.org/article/MED/22683884
http://www.sciencedirect.com/science/article/pii/S0166354212001301
http://hdl.handle.net/11336/198538

Variability and resistance mutations in the hepatitis C virus NS3 protease in patients not treated with protease inhibitors

Autori: Luciana Bonome Zeminian Juliana Lara Padovani Sílvia Maria Corvino a ďalší

Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 108, Iss 1, Pp 13-17 (2013)

Predmety: HCV genotype 1a, NS3 protease mutations, protease inhibitors, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216

Popis súboru: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100002; https://doaj.org/toc/0074-0276; https://doaj.org/toc/1678-8060

Prístupová URL adresa: https://doaj.org/article/281ab9a7b6674c6f80ae894b5f792026

Resistance-associated polymorphisms in Dutch hepatitis c genotype 1a patients with and without HIV infection

Autori: Lieveld, Faydra I. Swaans, Niels Newsum, Astrid M. a ďalší

Prispievatelia: Lieveld, Faydra I. Swaans, Niels Newsum, Astrid M. a ďalší

Predmety: Drug resistence, Genotype 1a, Hepatitis C virus, HIV, Q80k, General Medicine, Hepatology, Journal Article, Comparative Study

Popis súboru: image/pdf

Relation: https://dspace.library.uu.nl/handle/1874/341295

Dostupnosť: https://dspace.library.uu.nl/handle/1874/341295

Genomic characterization of Brazilian hepatitis C virus genotypes 1a and 1b

Autori: Ginabreda Mg Niel C Clara F. T. Yoshida

Zdroj: Brazilian Journal of Medical and Biological Research, Vol 30, Iss 3, p 339 (1997)

Predmety: hepatitis C virus, Adult, Male, 0301 basic medicine, Medicine (General), 0303 health sciences, Base Sequence, Genotype, QH301-705.5, Brazilian isolates, Molecular Sequence Data, nucleotide sequence, Genome, Viral, Hepacivirus, genotype 1b, genotype 1a, 3. Good health, 03 medical and health sciences, R5-920, DNA, Viral, Humans, Female, Biology (General), Brazil

Prístupová URL adresa: https://www.scielo.br/j/bjmbr/a/3nmwcsgxySnHWjSM3qQjgrd/?lang=en&format=pdf
https://pubmed.ncbi.nlm.nih.gov/9246231
https://doaj.org/article/404d0e5903154959bcfd9c31921208f4
https://www.ncbi.nlm.nih.gov/pubmed/9246231
http://europepmc.org/article/MED/9246231
http://www.scielo.br/j/bjmbr/a/3nmwcsgxySnHWjSM3qQjgrd/
https://www.scielo.br/j/bjmbr/a/3nmwcsgxySnHWjSM3qQjgrd/

Hepatitis C genotype 1a replicon improved through introduction of fitness mutations

Autori: Christian Voitenleitner Jill Bechtel Ann Arfsten a ďalší

Zdroj: BioTechniques, Vol 52, Iss 4, Pp 273-275 (2012)

Predmety: Hepatitis C, genotype 1a replicon, fitness, transient assay, Biology (General), QH301-705.5

Popis súboru: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

Prístupová URL adresa: https://doaj.org/article/158a17fc7b8d4344add5cb0992448489

Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors

Autori: De Luca, Andrea Di Giambenedetto, Simona Lo Presti, Alessandra a ďalší

Prispievatelia: De Luca, Andrea Di Giambenedetto, Simona Lo Presti, Alessandra a ďalší

Zdroj: Open Forum Infect Dis

Predmety: 0301 basic medicine, 0303 health sciences, drug resistance, Genotype 1a, protease, Drug resistance, HCV, Protease, Q80K, Oncology, Neurology (clinical), genotype 1a, Major Articles, 3. Good health, 03 medical and health sciences

Popis súboru: ELETTRONICO

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/26213689
https://pubmed.ncbi.nlm.nih.gov/26213689/
https://usiena-air.unisi.it/handle/11365/995726
https://core.ac.uk/display/53675670
https://www.ncbi.nlm.nih.gov/pubmed/26213689
https://europepmc.org/articles/PMC4511743
https://academic.oup.com/ofid/article-abstract/2/2/ofv043/1411454
https://hdl.handle.net/10807/193322
https://doi.org/10.1093/ofid/ofv043

Role of hepatocyte NADPH Oxidase 4 in oxidative stress and DNA damage by genotype 1a hepatitis C virus

Autori: Corder, Nicole Leanne Bidaud

Predmety: Molecular biology, Virology, Microbiology, core protein, genotype 1a, HCV, hepatitis C virus, NADPH oxidase, Nox4

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/22b679j9
https://escholarship.org/content/qt22b679j9/qt22b679j9.pdf

HCV genotype 1a shows a better virological response to antiviral therapy than HCV genotype 1b

Autori: Pellicelli Adriano M Romano Mario Stroffolini Tommaso a ďalší

Zdroj: BMC Gastroenterology, Vol 12, Iss 1, p 162 (2012)

Predmety: Genotype 1a, HCV genotype 1 subtypes, Sustained virological response, Antiviral therapy, Pegylated interferon, Diseases of the digestive system. Gastroenterology, RC799-869

Relation: http://www.biomedcentral.com/1471-230X/12/162; https://doaj.org/toc/1471-230X; https://doaj.org/article/dd6306878584495e934f8439030c2111

Dostupnosť: https://doi.org/10.1186/1471-230X-12-162
https://doaj.org/article/dd6306878584495e934f8439030c2111

The first complete genome sequence of HCV-1a from Pakistan and a phylogenetic analysis with complete genomes from the rest of the world

Autori: Hussain, Abrar Idrees, Muhammad

Predmety: HCV genotype 1a, Complete genome comparison, Evolutionary and Phylogenetic

Relation: http://www.virologyj.com/content/10/1/211

Dostupnosť: http://www.virologyj.com/content/10/1/211

Efficacy and safety of ombitasvir/paritaprevir/ritonavir and dasabuvir with low-dose ribavirin in patients with chronic hepatitis C virus genotype 1a infection without cirrhosis

Autori: Poordad, F. Sedghi, S. Pockros, P. J. a ďalší

Zdroj: Journal Articles

Predmety: Science & Technology, Life Sciences & Biomedicine, Gastroenterology & Hepatology, Infectious Diseases, Virology, genotype 1a, GEODE-II, hepatitis C virus, interferon-free therapy, low-dose ribavirin, ABT-450/R-OMBITASVIR, REGIMEN, HCV, Hepatology

Relation: https://academicworks.medicine.hofstra.edu/publications/5054

Dostupnosť: https://academicworks.medicine.hofstra.edu/publications/5054
https://my.hofstra.edu/hofapps/applications/ezproxy/indexMed.jsp?db_proxy=m&&db_url=onlinelibrary.wiley.com/doi/full/10.1111/jvh.13109