Výsledky vyhľadávania - "genetic risk"

A powerful framework for differential co-expression analysis of general risk factors.

Autori: Bass AJ Cutler DJ Epstein MP

Zdroj: Bioinformatics (Oxford, England) [Bioinformatics] 2025 Nov 01; Vol. 41 (11).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 9808944 Publication Model: Print Cited Medium: Internet ISSN: 1367-4811 (Electronic) Linking ISSN: 13674803 NLM ISO Abbreviation: Bioinformatics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Disease*/genetics , Gene Expression* , Gene Regulatory Networks* , Genetic Risk Score*, Humans ; Thyroid Neoplasms/genetics ; Computational Biology/methods ; Proto-Oncogene Proteins B-raf/genetics ; Mutation

Single nucleotide polymorphism SULT2A1 rs4149448 and genetic risk score as biomarkers of frailty and progression of chronic kidney disease.

Autori: Rodrigues HCN Coelho ASG Freitas ATVS a ďalší

Zdroj: Experimental gerontology [Exp Gerontol] 2025 Oct 01; Vol. 209, pp. 112836. Date of Electronic Publication: 2025 Jul 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Frailty*/genetics , Genetic Risk Score* , Renal Insufficiency, Chronic*/complications , Renal Insufficiency, Chronic*/genetics , Sulfotransferases*/genetics, Aged ; Female ; Humans ; Male ; Middle Aged ; Biomarkers ; Disease Progression ; Longitudinal Studies ; Polymorphism, Single Nucleotide ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/genetics

Genetic Risk for Open-Angle Glaucoma Subtypes Is Associated with Specific Visual Field Defect Classes.

Autori: Sekimitsu S Selvan K Zhao Y a ďalší

Zdroj: Ophthalmology [Ophthalmology] 2025 Sep; Vol. 132 (9), pp. 980-987. Date of Electronic Publication: 2025 Apr 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glaucoma, Open-Angle*/complications , Glaucoma, Open-Angle*/diagnosis , Glaucoma, Open-Angle*/genetics , Glaucoma, Open-Angle*/physiopathology , Visual Fields*/physiology , Genetic Risk Score* , Vision Disorders*/classification , Vision Disorders*/diagnosis , Vision Disorders*/genetics , Vision Disorders*/physiopathology, Cross-Sectional Studies ; Genotyping Techniques ; Visual Field Tests ; Genome-Wide Association Study ; Intraocular Pressure/physiology ; Logistic Models ; Datasets as Topic ; Follow-Up Studies ; Longitudinal Studies ; Humans ; Male ; Female ; Adult ; Middle Aged ; Aged

Predicting cancer risk using machine learning on lifestyle and genetic data.

Autori: Ahmed MA AbdelMoety A Soliman AMA

Zdroj: Scientific reports [Sci Rep] 2025 Aug 19; Vol. 15 (1), pp. 30458. Date of Electronic Publication: 2025 Aug 19.

Spôsob vydávania: Evaluation Study; Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Early Detection of Cancer*/methods , Neoplasms*/diagnosis , Risk Assessment*/methods , Predictive Learning Models* , Genetic Risk Score* , Life Style*, Humans ; Datasets as Topic ; Male ; Female ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Age Factors ; Exercise ; Alcohol Drinking ; Body Mass Index ; Logistic Models ; Support Vector Machine ; Decision Trees ; Boosting Machine Learning Algorithms

Genetic analysis of alcohol use disorder: GWAS of alcohol use disorders identification test (AUDIT) and polygenic risk scores in an east slavic population.

Autori: Trofimov M Kudriavskii V Shaheen L a ďalší

Zdroj: Drug and alcohol dependence [Drug Alcohol Depend] 2025 Aug 01; Vol. 273, pp. 112713. Date of Electronic Publication: 2025 May 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Ireland NLM ID: 7513587 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0046 (Electronic) Linking ISSN: 03768716 NLM ISO Abbreviation: Drug Alcohol Depend Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alcoholism*/genetics , Alcoholism*/diagnosis , Genetic Risk Score* , Genome-Wide Association Study*/methods , Eastern European People*/genetics, Adult ; Female ; Humans ; Male ; Middle Aged ; Cohort Studies ; Polymorphism, Single Nucleotide ; Risk Factors

A Phenome-Wide association study (PheWAS) of genetic risk for C-reactive protein in children of European Ancestry: Results from the ABCD study.

Autori: Norton SA Gorelik AJ Paul SE a ďalší

Zdroj: Brain, behavior, and immunity [Brain Behav Immun] 2025 Aug; Vol. 128, pp. 487-496. Date of Electronic Publication: 2025 Apr 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

Výrazy zo slovníka MeSH: C-Reactive Protein*/genetics , White People*/genetics , Genetic Risk Score*, Adolescent ; Child ; Female ; Humans ; Male ; Body Mass Index ; Brain ; Genome-Wide Association Study ; Inflammation/genetics ; Phenomics ; Phenotype

Recurrent Stroke Prediction by Applying a Stroke Polygenic Risk Score in the Japanese Population.

Autori: Kojima N Koido M He Y a ďalší

Korporácia: Kojima N Koido M He Y a ďalší

Zdroj: Stroke [Stroke] 2025 Jun; Vol. 56 (6), pp. 1483-1491. Date of Electronic Publication: 2025 Mar 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE

Výrazy zo slovníka MeSH: Genetic Risk Score* , Stroke*/genetics , Stroke*/epidemiology , Stroke*/diagnosis, Aged ; Female ; Humans ; Male ; Middle Aged ; Cohort Studies ; Japan/epidemiology ; Recurrence ; Risk Assessment ; East Asian People/genetics

Interaction between genetic risk score and dietary carbohydrate intake on high-density lipoprotein cholesterol levels: Findings from the study of obesity, nutrition, genes and social factors (SONGS).

Autori: Wuni R Curi-Quinto K Liu L a ďalší

Zdroj: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2025 Apr; Vol. 66, pp. 83-92. Date of Electronic Publication: 2025 Jan 10.

Spôsob vydávania: Journal Article; Multicenter Study

Informácie o časopise: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101654592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4577 (Electronic) Linking ISSN: 24054577 NLM ISO Abbreviation: Clin Nutr ESPEN Subsets: MEDLINE

Výrazy zo slovníka MeSH: Genetic Risk Score* , Dietary Carbohydrates*/administration & dosage , Cholesterol, HDL*/blood, Cross-Sectional Studies ; Humans ; Male ; Female ; Young Adult ; Polymorphism, Single Nucleotide ; Peru ; Urban Population ; Longitudinal Studies ; Cardiometabolic Risk Factors

Polygenic Risk Score for Metabolic Dysfunction-Associated Steatotic Liver Disease and Steatohepatitis: A Narrative Review.

Autori: Kanda T Sasaki-Tanaka R Abe H a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 May 28; Vol. 26 (11). Date of Electronic Publication: 2025 May 28.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Fatty Liver*/drug therapy , Fatty Liver*/genetics , Fatty Liver*/metabolism , Fatty Liver*/pathology , Genetic Risk Score*, Humans ; Genetic Variation ; Disease Progression ; Patient Acuity ; Genetic Markers

Development of a Japanese polygenic risk score model for amyloid-β PET imaging in Alzheimer's disease.

Autori: Kaishima M Ito J Takahashi K a ďalší

Zdroj: Alzheimer's research & therapy [Alzheimers Res Ther] 2025 May 22; Vol. 17 (1), pp. 112. Date of Electronic Publication: 2025 May 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE

Výrazy zo slovníka MeSH: Alzheimer Disease*/genetics , Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/metabolism , Amyloid beta-Peptides*/metabolism , Brain*/diagnostic imaging , Brain*/metabolism , Genetic Risk Score* , Positron-Emission Tomography*/methods, Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Cohort Studies ; Genome-Wide Association Study ; Japan ; Polymorphism, Single Nucleotide/genetics ; East Asian People/genetics

Assessment of a Polygenic Risk Score in Screening for Prostate Cancer.

Autori: McHugh JK Bancroft EK Saunders E a ďalší

Korporácia: McHugh JK Bancroft EK Saunders E a ďalší

Zdroj: The New England journal of medicine [N Engl J Med] 2025 Apr 10; Vol. 392 (14), pp. 1406-1417.

Spôsob vydávania: Journal Article; Observational Study

Informácie o časopise: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Early Detection of Cancer*/methods , Genetic Risk Score* , Multifactorial Inheritance* , Prostatic Neoplasms*/blood , Prostatic Neoplasms*/diagnosis , Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/pathology, Aged ; Humans ; Male ; Middle Aged ; Biopsy ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Multiparametric Magnetic Resonance Imaging ; Prostate/pathology ; Prostate/diagnostic imaging ; Prostate-Specific Antigen/blood ; Risk Assessment/methods ; Saliva/chemistry ; United Kingdom ; Case-Control Studies ; Prospective Studies

Assessment of polygenic risk score performance in East Asian populations for ten common diseases.

Autori: Jung HU Jung H Baek EJ a ďalší

Zdroj: Communications biology [Commun Biol] 2025 Mar 06; Vol. 8 (1), pp. 374. Date of Electronic Publication: 2025 Mar 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: East Asian People*/genetics , Genetic Risk Score*, Female ; Humans ; Male ; Asia, Eastern ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide ; Republic of Korea/epidemiology ; Risk Assessment

Polygenic Risk Score Added to Conventional Case Finding to Identify Undiagnosed Chronic Obstructive Pulmonary Disease.

Autori: Zhang J Hobbs BD Silverman EK a ďalší

Zdroj: JAMA [JAMA] 2025 Mar 04; Vol. 333 (9), pp. 784-792.

Spôsob vydávania: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

Výrazy zo slovníka MeSH: Genetic Risk Score* , Multifactorial Inheritance* , Pulmonary Disease, Chronic Obstructive*/diagnosis , Pulmonary Disease, Chronic Obstructive*/epidemiology , Pulmonary Disease, Chronic Obstructive*/genetics , Pulmonary Disease, Chronic Obstructive*/physiopathology, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Cross-Sectional Studies ; Forced Expiratory Volume/physiology ; Logistic Models ; Risk Assessment/methods ; Risk Factors ; Spirometry ; Surveys and Questionnaires ; Observational Studies as Topic ; Black or African American/genetics ; White/genetics ; Aged, 80 and over ; Massachusetts/epidemiology ; Multicenter Studies as Topic ; ROC Curve

Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores.

Autori: Liu T Sankareswaran A Paterson G a ďalší

Korporácia: Liu T Sankareswaran A Paterson G a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Jan 13; Vol. 15 (1), pp. 1168. Date of Electronic Publication: 2025 Jan 13.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diabetes Mellitus, Type 1*/genetics , Diabetes Mellitus, Type 1*/classification , Diabetes Mellitus, Type 1*/diagnosis , Diabetes Mellitus, Type 1*/epidemiology , Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/diagnosis , Diabetes Mellitus, Type 2*/classification , Genetic Risk Score*, Adolescent ; Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Asian People/genetics ; Bangladesh/ethnology ; Cohort Studies ; Pakistan/ethnology ; Risk Factors ; United Kingdom/epidemiology ; South Asian People

Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores.

Autori: Abramowitz SA Boulier K Keat K a ďalší

Korporácia: Abramowitz SA Boulier K Keat K a ďalší

Zdroj: JAMA [JAMA] 2025 Jan 07; Vol. 333 (1), pp. 60-70.

Spôsob vydávania: Evaluation Study; Journal Article; Research Support, N.I.H., Extramural

Informácie o časopise: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

Výrazy zo slovníka MeSH: Coronary Disease*/diagnosis , Coronary Disease*/epidemiology , Coronary Disease*/genetics , Genetic Predisposition to Disease* , Genetic Risk Score* , Multifactorial Inheritance*, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Cross-Sectional Studies ; Genotype ; Risk Assessment/methods ; Area Under Curve ; ROC Curve

Comparing Ancestry Standardization Approaches for a Transancestry Colorectal Cancer Polygenic Risk Score.

Autori: Rosenthal EA Hsu L Thomas M a ďalší

Zdroj: Genetic epidemiology [Genet Epidemiol] 2025 Jan; Vol. 49 (1), pp. e22590. Date of Electronic Publication: 2024 Sep 24.

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8411723 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2272 (Electronic) Linking ISSN: 07410395 NLM ISO Abbreviation: Genet Epidemiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Colorectal Neoplasms*/genetics , Genetic Risk Score*, Female ; Humans ; Male ; Middle Aged ; Genome-Wide Association Study/standards ; Polymorphism, Single Nucleotide ; Ethnicity/genetics ; Racial Groups/genetics

Development of a Prognostic Risk Model Based on Oxidative Stress-related Genes for Platinum-resistant Ovarian Cancer Patients.

Autori: Su H Hou Y Zhu D a ďalší

Zdroj: Recent patents on anti-cancer drug discovery [Recent Pat Anticancer Drug Discov] 2025; Vol. 20 (1), pp. 89-101.

Spôsob vydávania: Evaluation Study; Journal Article

Informácie o časopise: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101266081 Publication Model: Print Cited Medium: Internet ISSN: 2212-3970 (Electronic) Linking ISSN: 15748928 NLM ISO Abbreviation: Recent Pat Anticancer Drug Discov Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/genetics , Gene Expression Profiling*/methods , Prediction Algorithms* , Oxidative Stress*/genetics , Genetic Risk Score* , Drug Resistance, Neoplasm*/genetics, Humans ; Female ; Proportional Hazards Models ; Machine Learning ; Platinum Compounds/adverse effects ; Antineoplastic Agents/adverse effects

Type 2 Diabetes Polygenic Risk Score Interactions with Lifestyle Risk Factors in Black Americans.

Autori: Scadden AW Kakar A Litkowski EM a ďalší

Zdroj: Lifestyle genomics [Lifestyle Genom] 2025; Vol. 18 (1), pp. 90-97. Date of Electronic Publication: 2025 May 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: S. Karger AG Country of Publication: Switzerland NLM ID: 101716139 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2504-3188 (Electronic) Linking ISSN: 25043161 NLM ISO Abbreviation: Lifestyle Genom Subsets: MEDLINE

Výrazy zo slovníka MeSH: Black or African American*/genetics , Diabetes Mellitus, Type 2*/genetics , Diabetes Mellitus, Type 2*/epidemiology , Genetic Risk Score* , Life Style*, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Body Mass Index ; Cohort Studies ; Logistic Models ; Multifactorial Inheritance

Differential performance of polygenic risk scores for heart disease in Hispanic/Latino subgroups: Findings of the Hispanic Community Health Study/Study of Latinos.

Autori: Hutten CG Boehm FJ Smith JA a ďalší

Zdroj: HGG advances [HGG Adv] 2025 Oct 09; Vol. 6 (4), pp. 100486. Date of Electronic Publication: 2025 Jul 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101772885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-2477 (Electronic) Linking ISSN: 26662477 NLM ISO Abbreviation: HGG Adv Subsets: MEDLINE

Výrazy zo slovníka MeSH: Genetic Predisposition to Disease* , Heart Diseases*/genetics , Heart Diseases*/epidemiology , Hispanic or Latino*/genetics , Multifactorial Inheritance*, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Genetic Risk Score ; Myocardial Infarction/genetics ; Myocardial Infarction/epidemiology ; Risk Factors ; United States/epidemiology

Translational Research on Polygenic Risk Scores in Common Neurodegenerative Diseases - A Scoping Review Protocol.

Autori: Čižek Sajko M Suklan J Osmanović D a ďalší

Zdroj: Acta medica academica [Acta Med Acad] 2024 Dec; Vol. 53 (3), pp. 303-308.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Akademija nauka i umjetnosti Bosne i Hercegovine Country of Publication: Bosnia and Herzegovina NLM ID: 101587903 Publication Model: Print Cited Medium: Internet ISSN: 1840-2879 (Electronic) Linking ISSN: 18401848 NLM ISO Abbreviation: Acta Med Acad Subsets: MEDLINE

Výrazy zo slovníka MeSH: Genetic Risk Score* , Multifactorial Inheritance* , Neurodegenerative Diseases*/genetics , Translational Research, Biomedical*, Humans ; Alzheimer Disease/genetics ; Alzheimer Disease/diagnosis ; Amyotrophic Lateral Sclerosis/genetics ; Genetic Predisposition to Disease ; Multiple Sclerosis/genetics ; Parkinson Disease/genetics ; Parkinson Disease/diagnosis ; Research Design ; Risk Assessment ; Risk Factors ; Scoping Review as Topic