Suchergebnisse - "enzyme engineering"

A Cyanobacterial Screening Platform for Rubisco Mutant Variants

Autoren: Hoffmann, Ute A. Schuppe, Anna Z. Knave, Axel et al.

Quelle: ACS Synthetic Biology. 14(7):2619-2633

Schlagwörter: rubisco, high-throughput screening, cyanobacteria, Synechocystis, protein engineering, enzyme engineering

Dateibeschreibung: print

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-371874
https://doi.org/10.1021/acssynbio.5c00065

Computational exploration and design of HHDH variants with novel synthetically useful functionalities

Autoren: Estévez-Gay, Miquel

Weitere Verfasser: University/Department: Universitat de Girona. Institut de Química Computacional i Catàlisi, University/Department: Universitat de Girona. Departament de Química

Thesis Advisors: Osuna Oliveras, Sílvia

Quelle: TDX (Tesis Doctorals en Xarxa)

Schlagwörter: Dinàmica molecular, Molecular dynamics, Dinámica molecular, Biocatàlisi, Biocatalysis, Biocatálisis, Dinàmica conformacional, Conformational dynamics, Dinámica conformacional, Halohydrin dehalogenases, Enginyeria d'enzims, Enzyme engineering, Ingeniería de enzimas

Dateibeschreibung: application/pdf

Zugangs-URL: http://hdl.handle.net/10803/689477

Computational strategies for understanding the molecular basis of biochemical and biocatalytic processes

Autoren: Calvó-Tusell, Carla

Weitere Verfasser: University/Department: Universitat de Girona. Departament de Química

Thesis Advisors: Osuna Oliveras, Sílvia, García Borràs, Marc, Swart, Marcel, Institut de Química Computacional i Catàlisi

Quelle: TDX (Tesis Doctorals en Xarxa)

Schlagwörter: Dinàmica molecular, Dinámica molecular, Molecular dynamics, Biocatàlisi, Biocatálisis, Biocatalysis, Al·losteria, Alosterio, Allostery, Dinàmica conformacional, Dinámica conformacional, Conformational dynamics, Free energy landscape, Tècniques de mostreig millorades, Técnicas de mostreo mejoradas, Enhanced sampling techniques, Enginyeria d'enzims, Ingeniería de enzimas, Enzyme engineering

Dateibeschreibung: application/pdf

Zugangs-URL: http://hdl.handle.net/10803/688912

Semi-automated biofoundry workflows for sequence coevolution-guided isoprene synthase engineering

Autoren: Emelianov, Georgii Song, Dong-Uk Kamath, Aporva et al.

Quelle: Trends in Biotechnology

Schlagwörter: 31 Biological Sciences (for-2020), 3106 Industrial Biotechnology (for-2020), Bioengineering (rcdc), Genetics (rcdc), Biotechnology (rcdc), biofoundry, enzyme engineering, isoprene, isoprene synthase, 06 Biological Sciences (for), 09 Engineering (for), 10 Technology (for), Biotechnology (science-metrix), 3001 Agricultural biotechnology (for-2020), 3106 Industrial biotechnology (for-2020), 3206 Medical biotechnology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/12w5r0ch
https://escholarship.org/content/qt12w5r0ch/qt12w5r0ch.pdf

Efficient production of astaxanthin in Yarrowia lipolytica through metabolic and enzyme engineering

Autoren: Chalak Najat Abdullah Mengsu Liu Qihang Chen et al.

Quelle: Synth Syst Biotechnol
Synthetic and Systems Biotechnology, Vol 10, Iss 3, Pp 737-750 (2025)

Schlagwörter: Modular enzyme assembly, Subcellular organelles, Yarrowia lipolytica, QH301-705.5, Astaxanthin, Original Research Article, Biology (General), Enzyme engineering, TP248.13-248.65, Biotechnology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40248487
https://doaj.org/article/bbcdd791c5a7492f8cf4ce6ec362dc7a

From reactants to products: computational methods for biosynthetic pathway design

Autoren: Shaozhen Ding Dongliang Liu Yu Tian et al.

Quelle: Synth Syst Biotechnol
Synthetic and Systems Biotechnology, Vol 10, Iss 3, Pp 1038-1049 (2025)

Schlagwörter: QH301-705.5, Review Article, Methods of retrosynthetic analysis, Biology (General), Enzyme engineering, TP248.13-248.65, Biological big-data, Biotechnology

Zugangs-URL: https://doaj.org/article/a5076a45cbe74d0e8d8470c3d9dc52e4

Combined metabolic and enzymatic engineering for de novo biosynthesis of δ-tocotrienol in Yarrowia lipolytica

Autoren: Jinbo Xiang Mengsu Liu Xinglong Wang et al.

Quelle: Synth Syst Biotechnol
Synthetic and Systems Biotechnology, Vol 10, Iss 3, Pp 719-727 (2025)

Schlagwörter: Yarrowia lipolytica, Fed-batch fermentation, enzyme engineering, QH301-705.5, δ-tocotrienol, Original Research Article, Biology (General), Metabolic engineering, TP248.13-248.65, Biotechnology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40248488
https://doaj.org/article/6fa79137b5a249048cfede389d3a1f49

Engineering of thioesterase YciA from Haemophilus influenzae for production of carboxylic acids

Autoren: Pöschel, Laura Guevara-Martínez, Mónica Hörnström, David et al.

Quelle: Applied Microbiology and Biotechnology. 107(20):6219-6236

Schlagwörter: 3-Hydroxybutyric acid, Dicarboxylic acids, Enzyme engineering, Methylorubrum extorquens, Thioesterase

Dateibeschreibung: print

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-338509
https://doi.org/10.1007/s00253-023-12691-1

Harnessing aromatic properties for sustainable bio-valorization of lignin derivatives into flavonoids

Autoren: Si-Yu Zhu Na Li Zhi-Hua Liu et al.

Quelle: Green Carbon, Vol 3, Iss 2, Pp 172-195 (2025)

Schlagwörter: Flavonoids, Environmental sciences, Functionalization route, Biological lignin valorization, GE1-350, Enzyme engineering, Synthetic biology

Zugangs-URL: https://doaj.org/article/f57ce71ff2c64be7a5b4ed79d45bd9c6

Enhanced Production of (+)-Limonene through Targeted Engineering of Citrus sinensis Limonene Synthase

Autoren: Scipion, Clement Esque, Jérémy Borkar, Shreyash et al.

Weitere Verfasser: Scipion, Clement Esque, Jérémy Borkar, Shreyash et al.

Quelle: ACS Synthetic Biology. 14:2151-2161

Schlagwörter: [SDV] Life Sciences [q-bio], [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Monoterpene, Limonene synthase, Enzyme engineering, Limonene, Citrus sinensis

Zugangs-URL: https://hal.science/hal-05241703v1
https://doi.org/10.1021/acssynbio.5c00078

Exploring Natural Diversity of Limonene Synthases and Molecular Determinants Involved in Substrate Specificity in Escherichia coli

Autoren: Scipion, Clement Esque, Jérémy Borkar, Shreyash et al.

Weitere Verfasser: Scipion, Clement Esque, Jérémy Borkar, Shreyash et al.

Quelle: Journal of Agricultural and Food Chemistry. 73:13722-13735

Schlagwörter: enzyme engineering, limonene synthase, enantioselectivity, limonene, neryl pyrophosphate, geranyl pyrophosphate, Agastache rugosa, terpenoid, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, monoterpene, [SDV.BIO] Life Sciences [q-bio]/Biotechnology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40396278
https://hal.science/hal-05240689v1
https://doi.org/10.1021/acs.jafc.5c01640

Efflux pump knockout minimizes crosstalk and boosts response in transcription factor-based biosensors

Autoren: Jinju Lee Byeong-hyeon Yoo Eunjung Jeon et al.

Quelle: Journal of Biological Engineering, Vol 19, Iss 1, Pp 1-15 (2025)

Schlagwörter: Transcription factor-based biosensor, Efflux pump, High-throughput screening, Penicillin G acylase, Enzyme engineering, Biology (General), QH301-705.5

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1754-1611

Zugangs-URL: https://doaj.org/article/e981f5d17f1f4b4b986da55124eaef66

Revealing the essential role of the lid in mclPHA intracellular depolymerase from Pseudomonas putida KT2440

Autoren: Laura Isabel de Eugenio José Daniel Jiménez Elena Ramos et al.

Quelle: Applied Microbiology and Biotechnology, Vol 109, Iss 1, Pp 1-16 (2025)

Schlagwörter: PHA depolymerase, Random mutagenesis, Enzyme engineering, Bioplastic recycling, Microbiology, QR1-502, Biotechnology, TP248.13-248.65

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1432-0614

Zugangs-URL: https://doaj.org/article/14e06180226c472f8894c36f5b47594c

Discovery, design, and engineering of enzymes based on molecular retrobiosynthesis

Autoren: Ancheng Chen Xiangda Peng Tao Shen et al.

Quelle: mLife
mLife, Vol 4, Iss 2, Pp 107-125 (2025)

Schlagwörter: enzyme engineering, enzyme discovery, enzyme design, molecular retrosynthesis planning, Review, artificial intelligence, Microbiology, QR1-502

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40313979
https://doaj.org/article/950e7bb7673142a48349717e32db3243

Development of a green Komagataella phaffii cell factory for sustainable production of plant-derived sesquiterpene (–)-α-bisabolol

Autoren: Jintao Cheng Zhongji Pu Jiali Chen et al.

Quelle: Synth Syst Biotechnol
Synthetic and Systems Biotechnology, Vol 10, Iss 1, Pp 120-126 (2025)

Schlagwörter: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Microbial cell factory, QH301-705.5, (–)-α-Bisabolol, Original Research Article, Biology (General), Enzyme engineering, Metabolic engineering, TP248.13-248.65, Komagataella phaffii, Biotechnology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39493337
https://doaj.org/article/52eeaf36fb78484ca76bae95c0b02874

Automated Engineering Protein Dynamics via Loop Grafting: Improving Renilla Luciferase Catalysis

Autoren: Planas-Iglesias, Joan Majerova, Marika Pluskal, Daniel et al.

Quelle: ACS Catal
ACS Catalysis

Schlagwörter: loop grafting, protein dynamics, bifunctionalprotein chimeras, Renilla luciferase, enzyme engineering, bioluminescent catalytic activity

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40013243

Cell-Free Reaction System for ATP Regeneration from d-Fructose

Autoren: Kraußer, Franziska Rabe, Kenny Topham, Christopher et al.

Quelle: ACS synthetic biology. 14(4):1250-1263

Schlagwörter: acetyl phosphate synthesis | ATP cofactor regeneration | in vitro biocatalysis | molecular modeling | phosphoketolase | semirational enzyme engineering

Quantum chemistry and conformational sampling meet together : a powerful approach to study and design metalloprotein reactivity

Autoren: Monza, Emanuele

Weitere Verfasser: University/Department: Universitat Politècnica de Catalunya. Departament de Física

Thesis Advisors: Guallar i Tasies, Víctor

Quelle: TDX (Tesis Doctorals en Xarxa)

Schlagwörter: QM/MM, PELE, Computational protein design, In silico enzyme engineering, Laccases, Hemoglobin, Oxidoreductases, Allostery, Cooperativity, Biocatalysis, Àrees temàtiques de la UPC::Física

Dateibeschreibung: application/pdf

Zugangs-URL: http://hdl.handle.net/10803/404611
https://dx.doi.org/10.5821/dissertation-2117-106489

Conformational Selection in Biocatalytic Plastic Degradation by PETase

Autoren: Guo, Boyang Vanga, Sudarsana Reddy Lopez-Lorenzo, Ximena et al.

Quelle: ACS Catalysis. 12(6):3397-3409

Schlagwörter: PET, plastic biodegradation, conformational selection, gauche/trans, enzyme engineering

Dateibeschreibung: print

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-311888
https://doi.org/10.1021/acscatal.1c05548

Efficient synthesis of l-DOPA in Escherichia coli via cofactor and enzyme engineering

Autoren: Lihao Deng Jurong Ping Zhuoyuan Liu et al.

Quelle: Synthetic and Systems Biotechnology, Vol 11, Iss , Pp 226-236 (2026)

Schlagwörter: l-DOPA, Metabolic flux, Cofactor engineering, Enzyme engineering, Enzyme substrate tunnel, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405805X25001528; https://doaj.org/toc/2405-805X

Zugangs-URL: https://doaj.org/article/57a432668b0941d689d3f85c2ee92029