Suchergebnisse - "electrophile"

Molecular electrostatic potential as a guide to intermolecular interactions: challenge of nucleophilic interaction sites

Autoren: Brinck, Tore, Professor, 1965

Quelle: Pure and Applied Chemistry.

Schlagwörter: chemical interaction, electrophile, nucleophile, quantum chemistry, quantum science and technology, σ-hole bonding

Dateibeschreibung: print

Zugangs-URL: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-369851
https://doi.org/10.1515/pac-2025-0555

One-Pot Sequential Alcohol Activation and Nickel-Catalyzed Cross-Electrophile Coupling with Chlorosilanes

Autoren: Xiaojie Liu Biping Xu Martin Oestreich

Quelle: Org Lett

Schlagwörter: primary alcohols, cross-electrophile coupling, deoxygenative silylation, 500 Naturwissenschaften und Mathematik::540 Chemie::540 Chemie und zugeordnete Wissenschaften, chlorosilanes, nickel catalysis

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40160173

KEAP1 C151 active site catalysis drives electrophilic signaling to upregulate cytoprotective enzyme expression

Autoren: Matthew R. Schnell Tianhua Zhai Edwin R. Ragwan et al.

Quelle: Redox Biology, Vol 88, Iss , Pp 103906- (2025)

Schlagwörter: Sulforaphane, Omaveloxolone, Electrophile signaling, Cysteine sensor, KEAP1, NRF2, Medicine (General), R5-920, Biology (General), QH301-705.5

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231725004197; https://doaj.org/toc/2213-2317

Zugangs-URL: https://doaj.org/article/d5c737ab0e904914a8c280578d2bd5cc

Fatty acid nitroalkenes regulate intestinal lipid absorption

Autoren: Francisco J. Schopfer Lihong Teng Ahssan Sekandari et al.

Quelle: Journal of Lipid Research, Vol 66, Iss 8, Pp 100855- (2025)

Schlagwörter: Nitro-oleic acid, nitroalkenes, electrophile, chylomicron, fat absorption, lymph flow, Biochemistry, QD415-436

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227525001166; https://doaj.org/toc/0022-2275

Zugangs-URL: https://doaj.org/article/fee171b1879648f88b3c807408171f2d

Cobalt-Catalyzed Cross-Electrophile Dehydroxylative and Desulfonylative Allylation

Autoren: Haiyan Dong Xinran Dai Xinran Ding et al.

Schlagwörter: Biochemistry, Medicine, Cell Biology, Biotechnology, Immunology, Computational Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, synthesize multisubstituted γ, desulfonylative allylation herein, activated alkyl bromides, economical allylation reaction, electrophile desulfonylative allylation, reaction delivers, merging cross, highly regio, electrophile dehydroxylative, difluoro amides, diastereoselective manner, dehydroxylative coupling, concept study, catalyzed cross, also demonstrate, allyl alcohols

Verfügbarkeit: https://doi.org/10.1021/acs.joc.5c01201.s001
https://figshare.com/articles/journal_contribution/Cobalt-Catalyzed_Cross-Electrophile_Dehydroxylative_and_Desulfonylative_Allylation/30042911

Iron-Mediated One-Pot Dehydroxylative Cross-Electrophile Coupling of Alcohol with Disulfide for Thioether Synthesis by Using TCT as a Hydroxyl-Activating Agent

Autoren: Meng-Ke Xu Xuan-Qi Zhang Yong-Qing Xu et al.

Schlagwörter: Biochemistry, Medicine, Genetics, Pharmacology, Biotechnology, Developmental Biology, Mental Health, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, wide substrate scope, transiently formed tct, primary alkyl alcohol, pot dehydroxylative cross, , appropriate substrate, widely abundant, using tct, situ via, possibly serves, pivotal intermediate, excellent yields, electrophile thioetherification, electrophile coupling, efficient dehydroxythiolation, disulfides using, derived ether, cyanuric chloride, corresponding thioethers

Verfügbarkeit: https://doi.org/10.1021/acs.orglett.5c01308.s001
https://figshare.com/articles/journal_contribution/Iron-Mediated_One-Pot_Dehydroxylative_Cross-Electrophile_Coupling_of_Alcohol_with_Disulfide_for_Thioether_Synthesis_by_Using_TCT_as_a_Hydroxyl-Activating_Agent/28956489

Substrate-Photocatalyst Reactivity Matching Enables Broad Aryl Halide Scope in Light-Driven, Reductive Cross-Electrophile Coupling Using 13 C NMR as a Predictor

Autoren: Cameron H. Chrisman W. Zachary Elder Graham C. Haug et al.

Schlagwörter: Biochemistry, Molecular Biology, Physiology, Biotechnology, Evolutionary Biology, Sociology, Infectious Diseases, Chemical Sciences not elsewhere classified, valent nickel species, undergo side reactions, introduce two sets, important synthetic tool, generate reactive low, abundant building blocks, c – br, c chemical shift, substrate scope arising, minimize unwanted substrate, 3 , 13 , specific side reactivity, precious metal photocatalysts, driven methodologies utilizing, aryl halide reagents, electrophile coupling using, electrophile coupling, c nmr, unprotected bromoindoles, triethanolamine ), traditionally relied

Verfügbarkeit: https://doi.org/10.1021/acscatal.5c02019.s002
https://figshare.com/articles/journal_contribution/Substrate-Photocatalyst_Reactivity_Matching_Enables_Broad_Aryl_Halide_Scope_in_Light-Driven_Reductive_Cross-Electrophile_Coupling_Using_sup_13_sup_C_NMR_as_a_Predictor/28911782

A Nickel-Catalyzed Cross-Electrophile Coupling Reaction of 1,3-Dimesylates for Alkylcyclopropane Synthesis: Investigation of Stereochemical Outcomes and Radical Lifetimes

Autoren: Chen, Pan-Pan McGinnis, Tristan M Lin, Patricia C et al.

Quelle: ACS Catalysis. 13(8)

Schlagwörter: Organic Chemistry, Chemical Sciences, radical lifetime, radical clock, halogen-atom abstraction, cross-electrophile coupling, nickel, DFT calculations, Inorganic Chemistry, Chemical Engineering, Industrial biotechnology, Organic chemistry, Physical chemistry

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/8jp4t7c8
https://escholarship.org/content/qt8jp4t7c8/qt8jp4t7c8.pdf

Cascade Reactions of Indigo with an Allenylic Reactant

Autoren: Dyah U. C. Rahayu Christopher Richardson John B. Bremner et al.

Quelle: Molecules, Vol 30, Iss 14, p 2899 (2025)

Schlagwörter: indigo, cascade reaction, allenylic electrophile, benzoindolonaphthyridinedione, benzoazepinopyridoindolediones, Organic chemistry, QD241-441

Dateibeschreibung: electronic resource

Relation: https://www.mdpi.com/1420-3049/30/14/2899; https://doaj.org/toc/1420-3049

Zugangs-URL: https://doaj.org/article/aeef77e314e843669b260319985bc155

Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling

Autoren: Adolf Koudelka Gregory J. Buchan Veronika Cechova et al.

Quelle: Journal of Lipid Research, Vol 66, Iss 1, Pp 100705- (2025)

Schlagwörter: inflammation resolution, arachidonic acid, lipoxin, electrophile, formyl peptide receptor, lipoxygenase, Biochemistry, QD415-436

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227524002104; https://doaj.org/toc/0022-2275

Zugangs-URL: https://doaj.org/article/f4e9a37bd9494f20b7d9b64027f93048

Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography

Autoren: Mathas, Nicolas Braud, Emmanuelle Galardon, Erwan et al.

Weitere Verfasser: Mathas, Nicolas Braud, Emmanuelle Galardon, Erwan et al.

Quelle: ISSN: 0300-9084.

Schlagwörter: Electrophile stress, Enzyme assay, Guanosine dansyl, Guanosine fluorescein, Methylglyoxal, DJ-1, [CHIM]Chemical Sciences

Relation: info:eu-repo/semantics/altIdentifier/pmid/40523516; PUBMED: 40523516

Verfügbarkeit: https://hal.science/hal-05343900
https://hal.science/hal-05343900v1/document
https://hal.science/hal-05343900v1/file/1-s2.0-S030090842500118X-main-2.pdf
https://doi.org/10.1016/j.biochi.2025.06.005

Influence of a Two-Fold Ligation Pattern on Iron-Mediated Aryl-Heteroaryl Cross-Electrophile Couplings

Autoren: Djebbar, Faycel Chamoreau, Lise-Marie Lefèvre, Guillaume et al.

Weitere Verfasser: Djebbar, Faycel Chamoreau, Lise-Marie Lefèvre, Guillaume et al.

Quelle: ISSN: 2691-3704 ; JACS Au ; https://hal.science/hal-05345148 ; JACS Au, 2025, 5 (5), pp.2135-2147. ⟨10.1021/jacsau.5c00059⟩.

Schlagwörter: bisaryls, mechanisms, redox activity, cross-electrophile coupling, Iron, [CHIM]Chemical Sciences

Relation: info:eu-repo/semantics/altIdentifier/pmid/40443880; info:eu-repo/grantAgreement//852640/EU/Dominating redox mechanisms in iron-mediated C-C bond formations: reactivity, new paradigms and applications/DoReMI; PUBMED: 40443880; PUBMEDCENTRAL: PMC12117453

Verfügbarkeit: https://hal.science/hal-05345148
https://hal.science/hal-05345148v1/document
https://hal.science/hal-05345148v1/file/manuscript%20without%20highlight.pdf
https://doi.org/10.1021/jacsau.5c00059

SAR Studies around the SULT1A1-Activated Alkylator YC‑1 as Cytotoxic Agents against Biliary Tract Cancer Cells

Autoren: Ke Kong Wei Zhao Jonathan H. Shrimp et al.

Schlagwörter: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Mental Health, Infectious Diseases, Virology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, yc1 hepatic metabolism, nci compound collection, mutant cell lines, colorimetric biochemical assay, amino benzyl alcohols, key structural motifs, sar studies around, narrow sar around, sulfotransferase enzyme sult1a1, key analogs, smaller subset, selectively cytotoxic, reactive electrophile, quantitative high, like properties

Verfügbarkeit: https://doi.org/10.1021/acs.jmedchem.5c00489.s002
https://figshare.com/articles/journal_contribution/SAR_Studies_around_the_SULT1A1-Activated_Alkylator_YC_1_as_Cytotoxic_Agents_against_Biliary_Tract_Cancer_Cells/30136327

Water as an Electron Donor for Cross-Electrophile Coupling Reactions

Autoren: Jun-Li Li Can-Ming Zhu Huai-Gui Li et al.

Schlagwörter: Biochemistry, Medicine, Microbiology, Biotechnology, Inorganic Chemistry, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, increased disposal costs, divided electrochemical synthesis, viable coupling partners, 2 , electrophile coupling, coupling platform, wide array, stoichiometric reductants, significant waste, secondary bromides, pharmaceutically relevant, organic reagents, organic chemistry, generate electrons, fundamental construction, environmental pollution, electron donor, cathode surface, aryl halides, anode surface

Verfügbarkeit: https://doi.org/10.1021/jacs.5c12176.s001
https://figshare.com/articles/journal_contribution/Water_as_an_Electron_Donor_for_Cross-Electrophile_Coupling_Reactions/30068455

Intramolecular Ring Opening of Azetidines under Transition Metal-Free Conditions

Autoren: Lindsey G. DeRatt Colleen E. Keohane Zachary W. Boyer et al.

Schlagwörter: Biochemistry, Genetics, Molecular Biology, Evolutionary Biology, Computational Biology, Chemical Sciences not elsewhere classified, reports use lewis, readily available materials, membered ring systems, intramolecular ring opening, analogous oxetane substrates, 3 , azetidine ring, valuable synthons, transition metal, single step, prepared via, molecular complexity, increasingly exploited, hydroxymethyl handle, highly unusual, free conditions, electrophile coupling, described method, cyclized product

Verfügbarkeit: https://doi.org/10.1021/acs.joc.5c00851.s001
https://figshare.com/articles/journal_contribution/Intramolecular_Ring_Opening_of_Azetidines_under_Transition_Metal-Free_Conditions/29983568

Electroreductive Cross-Electrophile Coupling of Aromatic Ketones and N , N ‑Dimethylformamide Enabling the Synthesis of α‑Hydroxyaldehydes

Autoren: Jing Lei Fen Han Sheng Li et al.

Schlagwörter: Biochemistry, Medicine, Genetics, Pharmacology, Biotechnology, Infectious Diseases, Space Science, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, straightforward synthetic method, >‑ dimethylformamide enabling, electroreductive umpolung formylation, formylation reagents, electroreductive cross, >- dimethylformamide, toxic reagents, strong bases, n <, multistep reactions, electrophile coupling, efficient strategy, clinical drugs, aromatic ketones, added compounds

Verfügbarkeit: https://doi.org/10.1021/acs.joc.5c01485.s001
https://figshare.com/articles/journal_contribution/Electroreductive_Cross-Electrophile_Coupling_of_Aromatic_Ketones_and_i_N_i_i_N_i_Dimethylformamide_Enabling_the_Synthesis_of_Hydroxyaldehydes/29648254

Mechanistic Basis for Divergent Stereoselectivity in Intramolecular Ni-Catalyzed Cross-Electrophile Coupling Reactions

Autoren: Ethan T. A. Raffman Elizabeth R. Jarvo

Schlagwörter: Biophysics, Biochemistry, Molecular Biology, Immunology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, sequential reduction mechanism, different stereochemical outcomes, intermediate subsequently participates, arylzinc intermediate dominates, previously reported ni, intramolecular negishi coupling, electrophile coupling reaction, intramolecular ni, organonickel intermediate, stereoablative pathway, stereoablative mechanisms, one substrate, mechanistic investigation, mechanistic basis, enantiospecific reaction, either pathway, divergent stereoselectivity, competing rates, catalyzed cross, benzylic substituent, another substrate

Verfügbarkeit: https://doi.org/10.1021/acs.joc.5c00955.s001
https://figshare.com/articles/journal_contribution/Mechanistic_Basis_for_Divergent_Stereoselectivity_in_Intramolecular_Ni-Catalyzed_Cross-Electrophile_Coupling_Reactions/29610315

Development of a Diastereoselective Csp 2 –Csp 3 Cross-Coupling Reaction Inspired by Macrocyclic RiPP Natural Products

Autoren: Eleda V. Plouch Eliott Le Du Melanie Deville et al.

Schlagwörter: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, translationally modified peptides, rapidly growing subclass, coupling reaction inspired, 3 , electrophile coupling, significant potential, ripps ), ribosomally synthesized, report presents, new pharmaceuticals, key β, efficient synthesis, diastereoselective csp, class using

Verfügbarkeit: https://doi.org/10.1021/acs.orglett.5c02198.s001
https://figshare.com/articles/journal_contribution/Development_of_a_Diastereoselective_Csp_sup_2_sup_Csp_sup_3_sup_Cross-Coupling_Reaction_Inspired_by_Macrocyclic_RiPP_Natural_Products/29525469

Pd-Catalyzed Convergent Coupling of Alkenyl Bromide, Isocyanides, and Thiocarboxylate to Synthesize Thiophene Derivatives

Autoren: Zeyuan Fu Qintong Huang Liangbin Huang

Schlagwörter: Biochemistry, Molecular Biology, Biotechnology, Space Science, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, latter functioning dually, catalyzed convergent coupling, catalyzed three, trisubstituted thiophenes, sulfur donor, streamlined approach, potassium thiocarboxylates, method represents, high step, good yields, efficient synthesis, alkenyl bromide, acyl electrophile

Verfügbarkeit: https://doi.org/10.1021/acs.orglett.5c02155.s001
https://figshare.com/articles/journal_contribution/Pd-Catalyzed_Convergent_Coupling_of_Alkenyl_Bromide_Isocyanides_and_Thiocarboxylate_to_Synthesize_Thiophene_Derivatives/29476833

Electroreductive Borylation of Chloroalkanes and Polyvinyl Chloride Plastics

Autoren: Immaculata O. Onuigbo Jordan L. Zackasee Valmuri Srivardhan et al.

Schlagwörter: Biophysics, Biochemistry, Medicine, Genetics, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Developmental Biology, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, distinct bulk properties, conventional grignard formation, 0 , grignard intermediates, vinyl chloride, typically mixed, report details, rapidly generated, organomagnesium intermediate, micellar conformation, metals failed, increased plasticity, essential plasticizers, employing mg, create materials, cathodic surface, boron electrophile, approach exposes

Relation: https://figshare.com/articles/journal_contribution/Electroreductive_Borylation_of_Chloroalkanes_and_Polyvinyl_Chloride_Plastics/29402396

Verfügbarkeit: https://doi.org/10.1021/jacs.5c07692.s001
https://figshare.com/articles/journal_contribution/Electroreductive_Borylation_of_Chloroalkanes_and_Polyvinyl_Chloride_Plastics/29402396